Identifiers and Description

Gene Model Identifier

TTHERM_00118700

Standard Name

ETU1 (Epsilon-TUbulin 1)

Aliases

PreTt27186 | 8.m00446 | 3812.m02478

Description

Epsilon-tubulin protein, tubulin/FtsZ family; GTPase domain containing protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• protein complex (IEA) | GO:0043234

Molecular Function

• GTP binding (IEA) | GO:0005525
• GTPase activity (IEA) | GO:0003924

Biological Process

• protein polymerization (IEA) | GO:0051258

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00118700

WebApollo

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Tetrahymena Stock Center

• ( SD03320 ) Micronucleus: TTHERM_00118700[Δ::NEO2] Macronucleus: none
• ( SD03321 ) Micronucleus: TTHERM_00118700[Δ::NEO2] Macronucleus: none
• ( SD03322 ) Micronucleus: TTHERM_00118700[Δ::NEO2] Macronucleus: TTHERM_00118700T150V

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Stentor Coeruleus	SteCoe_375	0
Tetrahymena borealis	EI9_03868.1	9.997093137033517e-262	tubulin/FtsZ family, GTPase do main-containing protein (481 a a)
Oxytricha	Contig18792.0.g34	6.001815994751712e-130	Tubulin/FtsZ family, GTPase do main
WormBase	WBGene00006538	1.999469658314961e-75	locus:tbb-4 Tubulin beta-4 c hain status:Partially_confir med UniProt:P41937 protein _id:CAA86310.1
SGD	YML124C	3.000809166761476e-75	TUB3 Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which poly merizes to form microtubules; expressed at lower level than Tub1p
DictyBase	DDB_G0269196	2.9990539278805726e-74	tubB on chromosome: 1 position 3261649 to 3263130

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23704354: Ross I, Clarissa C, Giddings TH, Winey M (2013) ?-tubulin is essential in Tetrahymena thermophila for the assembly and stability of basal bodies. Journal of cell science 126(Pt 15):3441-51
2. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,

Sequences

>TTHERM_00118700(coding)
ATGAGAGAACTTATAACTATTTAAGTAGGTCAGTGTGGAAACTAAATTGGTGCTAAATTC
TGGGAATTAGCGATAAAAGAACACTCAAAATATAATAAATCTTCTGTCTATGATGATGCT
CTTTCTTCTTTTTTCCGTAATATAGATAAGAGCTCTAAAGGACATGAATTAAAAGTTGGC
AGTGAAATAATCAACTTGAAGGCAAGATCTATAATAGTTGATATGGAAGAGGGTGTCACA
AATCAACTTTTAAAGAGTGATATTGGAGATCTTTTTGATTAGAGATAGTTCATAAATGAT
GTGAGTGGTGCAGGAAATAATTGGGCTCATGGTCACTTTTTCTATGGAAATAAGTATAGA
GATAATATGAGTGAAAGAATCAGGAAAGCTGTAGAATAATGTGATTCTTTGTAATGTTTT
TTCTTGATGCATTCTTTAGGAGGAGGAACAGGATCAGGATTAGGAACATTCCTACTCTCA
TTAATTGAAGATGAATATCCCGATGTTTATAGATTTACAGCTTCTGTATTTCCTCAAAAG
GATGATGATGTTATAACCTCACCTTATAATAGCTTTTTTTCTTTGTATGAGCTAGCTAAG
CATGCCGATTGTGTGTTTCCTATTGATAATTAAGCTTTAATGAATATTTGCTACTAAATT
GATAATCCAAACAAGGTAAAGTTGGCAAAGGATAATATAAATGTAAGCAAAGAAGAAGAA
ATAAAAATAATGATGAACAAAGGTTCTAAGATAACTTAAGCAGGAACTGAAGAAAAGAAA
GAAAAGCCTTTTGATAAAATGAATAATATTATTGCACATTTACTCAGTAATATTACATGC
TCTATGAGATTTGAGGGAGTTCTAAATGTTGATCTTAATGAAATAACAATGAATTTAGTT
CCTTATCCTGATTTACATTTCTTAATATCAAGTATAGCTCCGCTTTATTCCTTATCGGAT
AGCAACTTATAGCCTAGAAGATTAGATTAAATGTTTAAAGACTGCTATCATCCTGATTAT
TAGCTAGTTAGTGTGAATCCCTTTTAAAATAAGTATTTAGCAGTAGGATTAATGGTAAGG
GGATCAGTTCCCTTTTCTGATGTAAATAGAAATATCAAAAAGCTTAGAAGTGAGTTAAAT
ATGATTTACTGGAACCAAGAAGGTTTTAAGTACGGTATATGCAACACACCTCCTATAGGC
CAACCTTACTCCTTGCTATGCTTGGCAAATAATACTGCAATAAGAGATCAGTTTTCGACT
ATGGTAGAGAGATTCAACAAACTATATAAAAGGAAGGTGTTTGTTCATCATTATACAGAA
TATATGGATGCAAAGCATTTTGACGAGGCTTTGAATTCTATCACATCTCTTATAAGTAAA
TATGAAGAACTCCATAAAGCTGAAGAACCTTCTTCTCAACCAAGATTGAAACCTTTGATT
TGA

>TTHERM_00118700(protein)
MRELITIQVGQCGNQIGAKFWELAIKEHSKYNKSSVYDDALSSFFRNIDKSSKGHELKVG
SEIINLKARSIIVDMEEGVTNQLLKSDIGDLFDQRQFINDVSGAGNNWAHGHFFYGNKYR
DNMSERIRKAVEQCDSLQCFFLMHSLGGGTGSGLGTFLLSLIEDEYPDVYRFTASVFPQK
DDDVITSPYNSFFSLYELAKHADCVFPIDNQALMNICYQIDNPNKVKLAKDNINVSKEEE
IKIMMNKGSKITQAGTEEKKEKPFDKMNNIIAHLLSNITCSMRFEGVLNVDLNEITMNLV
PYPDLHFLISSIAPLYSLSDSNLQPRRLDQMFKDCYHPDYQLVSVNPFQNKYLAVGLMVR
GSVPFSDVNRNIKKLRSELNMIYWNQEGFKYGICNTPPIGQPYSLLCLANNTAIRDQFST
MVERFNKLYKRKVFVHHYTEYMDAKHFDEALNSITSLISKYEELHKAEEPSSQPRLKPLI

>TTHERM_00118700(gene)
ATGAGAGAACTTATAACTATTTAAGTAGGTCAGTGTGGAAACTAAATTGGTGCTAAATTC
TGGGAATTAGCGATAAAAGAACACTCAAAATATAATAAATCTTCTGTCTATGATGATGCT
CTTTCTTCTTTTTTCCGTAATATAGATAAGAGGTATTTTTGAATTGATCAATTGTATTAA
TCACTATATAATTTATGATTCATAATAGCTCTAAAGGACATGAATTAAAAGTTGGCAGTG
AAATAATCAACTTGAAGGCAAGAGTAAATAAATAAATTATAGAAAAATATAATTAATTTA
ATAACAATTCAGTCTATAATAGTTGATATGGAAGAGGGTGTCACAAATCAACTTTTAAAG
AGTGGTAAAAAATGAATACAAAATCAAACAATTCAATTTATTAGAAAATTGTTCTAACTA
AGACTTTCTATTTATTTAAATAAGATATTGGAGATCTTTTTGATTAGAGATAGTTCATAA
ATGATGTGAGTGGTGCAGGAAATAATTGGTACATTCAAATATAGCTCTATATATTAAATA
ATTTAATTTTATTAAATAAGGGCTCATGGTCACTTTTTCTATGGAAATAAGTATAGAGAT
AATATGAGTGAAAGAGTAAATAAATACTTTTTAAAAAACTTTAAAATTCAAAAGTAGTTT
TTTATATGAAATTATAAATAATAATAAACAGATCAGGAAAGCTGTAGAATAATGTGATTC
TTTGTAATGTTTTTTCTTGATGCATTCTTTAGGAGGAGGAACAGGATCAGGATTAGGAAC
ATTCCTACTCTCATGTATATATATACTTTTAAAAGTACTTTAAAATAATAGATTCATATA
AATTAAAAAGTAATTGAAGATGAATATCCCGATGTTTATAGATTTACAGCTTCTGTATTT
CCTCAAAAGGATGATGATGTTATAACCTCACCTTATAATAGGTAATAATGCATATTTAAT
AGAATTAATAATAATATGTTTTTTTGCTATTTAAATTTAACTTTATTAGAGAATAATAAA
TTACACAAATATTTTATCTGATTATGTTTATAAAAAAATAAGCTTTTTTTCTTTGTATGA
GCTAGCTAAGCATGCCGATTGTGTGTTTCCTATTGATAATTAAGCTTTAATGAATATTTG
CTACTAAATTGATAATCCAAACAAGGTAAAGTTGGCAAAGGATAATATAAATGTAAGCAA
AGAAGAAGAAATAAAAATAATGATGAACAAAGGTTCTAAGATAACTTAAGCAGGAACTGA
AGAAAAGAAAGAAAAGCCTTTTGATAAAATGAATAATATTATTGCACATTTACTCAGTAA
TATTACATGGTAAATTTATTTGAGAAAATGGCTCATAAAAATTAATTTGAATTTAAATTA
AAGCTCTATGAGATTTGAGGGAGTTCTAAATGTTGATCTTAATGAAATAACAATGAATTT
AGTTCCTTATCCTGATTTACATTTCTTAATATCAAGTATAGCTCCGCTTTATTCCTTATC
GGATAGCAACTTATAGCCTAGAAGATTAGATTAAATGTTTAAAGACTGCTATCATCCTGA
TTATTAGCTAGTTAGTGTGAATCCCTTTTAAAATAAGTATTTAGCAGTAGGATTAATGGT
AAGGGGATCAGTTCCCTTTTCTGATGTAAATAGAAATATCAAAAAGCTTAGAAGTGAGTT
AAATATGATTTACTGGAACCAAGAAGGTTTTAAGTACGGTATATGCAACACACCTCCTAT
AGGCCAAGTAATTAAATTTTTTTTAATTAAATTATTTATTTTAAAAAAATATAAAAAAAG
CCTTACTCCTTGCTATGCTTGGCAAATAATACTGCAATAAGAGATCAGTTTTCGACTATG
GTAGAGAGATTCAACAAACTATATAAAAGGAAGGTAAAAATTTAATAAAGGAATTATCAA
TTTAACAATTTTATTTTTAGGTGTTTGTTCATCATTATACAGAATATATGGATGCAAAGC
ATTTTGACGAGGCTTTGAATTCTATCACATCTCTTATAAGTAAATATGAAGAACTCCATA
AAGCTGAAGAACCTTCTTCTCAACCAAGATTGAAACCTTTGATTTGA