Identifiers and Description

Gene Model Identifier

TTHERM_00486480

Standard Name

ENO1 (ENOlase 1)

Aliases

PreTt19579 | 59.m00217 | 3680.m00074

Description

ENO1 carboxy-terminal TIM barrel domain enolase; Enolase; portions of this gene may have been laterally transferred

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cilium (IDA) | GO:0005929 | Ref:17785518
• phosphopyruvate hydratase complex (IEA) | GO:0000015
• microtubule basal body (IDA) | GO:0005932 | Ref:17785518

Molecular Function

• phosphopyruvate hydratase activity (IEA) | GO:0004634
• magnesium ion binding (IEA) | GO:0000287
• 5'-3' exoribonuclease activity (ISS) | GO:0004534 | Ref:11526220

Biological Process

• glycolytic process (IEA) | GO:0006096

Domains

• ( PF03952 ) Enolase, N-terminal domain
• ( TIGR01060 ) phosphopyruvate hydratase
• ( PF00113 ) Enolase, C-terminal TIM barrel domain
• ( PF01188 ) Mandelate racemase / muconate lactonizing

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.1%

TetraMine Data

TTHERM_00486480

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Stentor Coeruleus	SteCoe_4496	0
Tetrahymena borealis	EI9_12148.1	9.997093137033517e-262	enolase (441 aa)
DictyBase	DDB_G0283137	9.997093137033517e-262	enoA on chromosome: 4 position 225309 to 226956
Oxytricha	Contig15891.0.g72	9.997093137033517e-262	Enolase, C-terminal TIM barrel domain
WormBase	WBGene00011884	1.9999987447608204e-178	locus:enol-1 Enolase statu s:Confirmed UniProt:Q27527 protein_id:CAA92692.1
SGD	YGR254W	2.0002969069156684e-168	ENO1 Enolase I, a phosphopyruv ate hydratase that catalyzes t he conversion of 2-phosphoglyc erate to phosphoenolpyruvate d uring glycolysis and the rever se reaction during gluconeogen esis; expression is repressed in response to glucose

General Information

No Data fetched for General Information

Associated Literature

1. Ref:17785518: Kilburn CL, Pearson CG, Romijn EP, Meehl JB, Giddings TH, Culver BP, Yates JR, Winey M (2007) New Tetrahymena basal body protein components identify basal body domain structure. The Journal of cell biology 178(6):905-12
2. Ref:11526220: Keeling PJ and Palmer JD (2001) Lateral transfer at the gene and subgenic levels in the evolution of eukaryotic enolase. Proc Natl Acad Sci U S A 98(19):10745-50

Sequences

>TTHERM_00486480(coding)
ATGGCTACTATTAAAGATATCAAAGCTAGAGAAATACTAGATTCTAGAGGTAATCCTACT
GTTGAAGTTGATTTGACAGTAGATAATGGTCAAGTTTTTAGAGCTGCTGTTCCTTCTGGT
GCTTCAACAGGTATCTATGAAGCCTGTGAACTTAGAGACGGGGATAATCACAGATATTTA
GGGAAAGGTGTTTTGAAGGCTGTAAACAATGTGAACACCATCATTAAACCTCATTTAATT
GGTAAAAATGTTACTGAATAAGAATAATTAGATAAGTTAATGGTAGAATAGCTTGATGGA
ACTAAAAATGAATGGGGTTGGTGCAAAAGCAAATTAGGAGCAAATGCTATTTTAGCAGTT
TCTATGGCTGTTGCCAGAGCTGCCGCAGCTCATAAGAACCTTCCTTTATACAAATACTTG
TCTCATTTGAATGGATAAGACAACCTAACCCAATTCAATTTACCTCTTCCATTCTTCAAT
GTCATTAATGGTGGAAAGCATGCAGGAAACAAATTAGCTTTCTAAGAGTTTATGTTCACA
CCATGCGGTGCATCTAACTTTGCAGAAGGTCTAAGAATGGGTGCTGAGGTTTATCACAAC
TTAAAGAAAGTAATTGAAAAAAAGTACGGACAAACAGCTACTAATGTAGGTGATGAAGGA
GGTTTTGCCCCAGATACTAGTAATCCAGATGAAGCATTAGAATTACTAGTTGAAGCTATC
AAGAAGGCAGGTCATGAAGGAAAGATTAAAATATCTATGGATGTTGCAGCTTCTGAATTC
TACGACGCTAAAACTAAGCTTTATGATTTAGATTTTAAGAATAGTAACTCAGATGGTAAG
CATAAGTTAACTTCTGAATAGTTAGTTGAATACTTTGCCAATTTAGTTTCAAAATATCCA
ATTTTTTCAATTGAAGATCCTTTCGACTAGGATGACTGGGCTGCTTATGCTCAATTGACT
GCTCGTATTGGTAATTAAGTCAAGATTGTTGGTGATGACTTACTTGTTACTAACCCTTTA
CGTGCAGAAAAAGCTATTTAAGAAAAAGCCTGTAATTATCTTCTACTTAAAGTCAATCAA
ATTGGAACAGTAACAGAAGCAATTTAAACATATCAAATTGTCTCTAAAGCCAACTTTGGA
ACTATGGTCTCACATAGATCAGGTGAAACTGAAGATACTTTCATAGCTGATTTAGTTGTA
GGAATAGGTGCTGCTACAATTAAAACTGGTGCTCCCTGCAGATCTGAAAGATTAGCTAAA
TATAATTAGCTTATCAGAATTGAAGAAGAGCTTGGTCAAAATTCTACTTATGGAAAAAAT
CACTGA

>TTHERM_00486480(protein)
MATIKDIKAREILDSRGNPTVEVDLTVDNGQVFRAAVPSGASTGIYEACELRDGDNHRYL
GKGVLKAVNNVNTIIKPHLIGKNVTEQEQLDKLMVEQLDGTKNEWGWCKSKLGANAILAV
SMAVARAAAAHKNLPLYKYLSHLNGQDNLTQFNLPLPFFNVINGGKHAGNKLAFQEFMFT
PCGASNFAEGLRMGAEVYHNLKKVIEKKYGQTATNVGDEGGFAPDTSNPDEALELLVEAI
KKAGHEGKIKISMDVAASEFYDAKTKLYDLDFKNSNSDGKHKLTSEQLVEYFANLVSKYP
IFSIEDPFDQDDWAAYAQLTARIGNQVKIVGDDLLVTNPLRAEKAIQEKACNYLLLKVNQ
IGTVTEAIQTYQIVSKANFGTMVSHRSGETEDTFIADLVVGIGAATIKTGAPCRSERLAK
YNQLIRIEEELGQNSTYGKNH

>TTHERM_00486480(gene)
ATGGCTACTATTAAAGATATCAAAGCTAGAGAAATACTAGATTCTAGAGGTAATCCTACT
GTTGAAGTTGATTTGACAGTAGATAATGGTCAAGTTTTTAGAGCTGCTGTTCCTTCTGGT
GCTTCAACAGGTATCTATGAAGCCTGTGAACTTAGAGACGGGGATAATCACAGATATTTA
GGGAAAGGTGTTTTGAAGGCTGTAAACAATGTGAACACCATCATTAAACCTCATTTAATT
GGTAAAAATGTTACTGAATAAGAATAATTAGATAAGTTAATGGTAGAATAGCTTGATGGA
ACTAAAAATGAATGGGGTTGGTGCAAAAGCAAATTAGGAGCAAATGCTATTTTAGCAGTT
TCTATGGCTGTTGCCAGAGCTGCCGCAGCTCATAAGAACCTTCCTTTATACAAGTAAATA
TTTTTAAAATTCTATTTCAAATTATAAAAAGCCTCTTTACTTTATTTAAAAACCAAATCT
TATCATCTTTGCATTAACATTTTTTATGGAAGATTTTAAAACTTTGCAGCAATAAATACT
TAGGTTAAAAGCTTCATATAAACAAAAAAACATGAAATTATTTATTCCTAACTTAATATA
AATAAAATTAAACTAGATACTTGTCTCATTTGAATGGATAAGACAACCTAACCCAATTCA
ATTTACCTCTTCCATTCTTCAATGTCATTAATGGTGGAAAGCATGCAGGAAACAAATTAG
CTTTCTAAGAGTTTATGTTCACACCATGCGGTGCATCTAACTTTGCAGAAGGTCTAAGAA
TGGGTGCTGAGGTTTATCACAACTTAAAGAAAGTAATTGAAAAAAAGTACGGACAAACAG
CTACTAATGTAGGTGATGAAGGAGGTTTTGCCCCAGATACTAGTAATCCAGATGAAGCAT
TAGAATTACTAGTTGAAGCTATCAAGAAGGCAGGTCATGAAGGAAAGATTAAAATATCTA
TGGATGTTGCAGCTTCTGAATTCTACGACGCTAAAACTAAGCTTTATGATTTAGATTTTA
AGAATAGTAACTCAGATGGTAAGCATAAGTTAACTTCTGAATAGTTAGTTGAATACTTTG
CCAATTTAGTTTCAAAATATCCAATTTTTTCAATTGAAGATCCTTTCGACTAGGATGACT
GGGCTGCTTATGCTCAATTGACTGCTCGTATTGGTAATTAAGTCAAGATTGTTGGTGATG
ACTTACTTGTTACTAACCCTTTACGTGCAGAAAAAGCTATTTAAGAAAAAGCCTGTAATT
ATCTTCTACTTAAAGTCAATCAAATTGGAACAGTAACAGAAGCAATTTAAACATATCAAA
TTGTCTCTAAAGCCAACTTTGGAACTATGGTCTCACATAGATCAGGTGAAACTGAAGATA
CTTTCATAGCTGATTTAGTTGTAGGAATAGGTGCTGCTACAATTAAAACTGGTGCTCCCT
GCAGATCTGAAAGATTAGCTAAATATAATTAGCTTATCAGAATTGAAGAAGAGCTTGGTC
AAAATTCTACTTATGGAAAAAATCACTGA