Identifiers and Description

Gene Model Identifier

TTHERM_00859260

Standard Name

EF1BL1 (Elongation Factor 1 Beta Like 1)

Aliases

PreTt09088 | 152.m00108

Description

EF-1 guanine nucleotide exchange domain protein; EF-1 guanine nucleotide exchange domain containing protein; involved in guanine nucleotide exchange to activate EF1A from its inactive (GDP) form to its active (GTP) form so that it can readily associate with an aminoacyl-tRNA

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cytoplasm (IDA) | GO:0005737 | Ref:SUPR000376
• eukaryotic translation elongation factor 1 complex (IEA) | GO:0005853

Molecular Function

• guanyl-nucleotide exchange factor activity (IDA) | GO:0005085 | Ref:SUPR000376
• translation elongation factor activity (IEA) | GO:0003746

Biological Process

• translational elongation (IEA) | GO:0006414
• translation (IDA) | GO:0006412 | Ref:SUPR000376

Domains

• ( PF00736 ) EF-1 guanine nucleotide exchange domain
• ( TIGR00489 ) translation elongation factor aEF-1 beta

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 14.5%

TetraMine Data

TTHERM_00859260

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_07206.1	2.0005752503420762e-105	EF-1 guanine nucleotide exchan ge domain-containing protein ( 226 aa)
Oxytricha	Contig19220.0.g56	9.001422350855153e-28	EF-1 guanine nucleotide exchan ge domain
WormBase	WBGene00018846	3.0002687256732656e-20	locus:eef-1B.1 Probable elon gation factor 1-beta/1-delta 1 status:Confirmed UniProt: P34460 protein_id:CCD63459.1
DictyBase	DDB_G0284035	0.000000000000001999258566166494	efa1B on chromosome: 4 positio n 1535647 to 1536451
SGD	YAL003W	0.0000000000000030004923591262316	EFB1 Translation elongation fa ctor 1 beta; stimulates nucleo tide exchange to regenerate EF -1 alpha-GTP for the next elon gation cycle; part of the EF-1 complex, which facilitates bi nding of aminoacyl-tRNA to the ribosomal A site
Stentor Coeruleus	SteCoe_13681	0.000000000013887943864964021

General Information

No Data fetched for General Information

Associated Literature

1. Ref:SUPR000376

Sequences

>TTHERM_00859260(coding)
ATGAATAAAGAAATAGTATATTTATAATATGAGATGGATTGGTTGCTTGGTTGCTTGTTT
AATAGATTGATAGAAACTTAAAAAACTATAAATTTCTTTTTAAGTCAATTCCTTCTTTTT
TTCCATTCGATAAACAAATATCTTTTTTTTTTTGAGACAATCAAAAAAATATATATATTT
TTGTTTGTTTGCTTTTTTAGATTATTTTTAGATTTGCATTTGTACGTATTTTTAATATAC
ATTAAAAAATAAATTCTCTGGGAAAAGATATATAAAGTAAATTTAATAAATTATTATCAA
AAACTAAAAAACAAAAAGCAAAAAACAAACCAATTCTCTAAAATGACTTTCTCTGCTACC
GACCTCCCCACCCTCGAAAAGCACTTAGCTGCCCACACCTACCTTTCCGGTACTGATAAG
CCCGCTAAGATTGATGCTTAAATTGCCACCGAACTCAAGGATAAGAAGGTTGCCCTCAAC
GCCGCCACCCACCCCAACGTCTATGCCTGGTTCAGCTTCATCGGTTTATTCACCCCCGAA
GCTCAAAATACCTGGGCTGATGTTGCTCCCGTCGCCGTCCCCGTTGCTGCCAAGAAGGAA
GCCAAGAAGGAAACCAAGACCGACGATGTCGATCTTTTCGGTGATGATGATGAAGAAGAT
GCTGAAGCTGAAGCTTTGAGAGAAAAGAAGAGACTCGAAGCCGTCGCTGCCAAGGAAGCT
AGAGATGGTAAGAAGAAGAAGGCTATTGCCAAGACTATCCTCGTCTTCAACGTCAAGGTC
TTCGAAGCTGAATAAGACTTAGACGCTTTGGCCAAGAAGATCTACGAAACCATCCAACTC
GACGGTTTGGTCTGGAACAAGGAACACAAGAAGATCCCCGTTGCCTTCGGTGTCTTCATG
CTCCAAATGGGTTGCATCATTGAAGACGATAAGGTCAACACCGACAGTATCTTCGAACCC
ATCCAATCTTGGGAAGATGAAGTCCAATCCGTTGATGTTGAAACCATGCAAAAACTTTGA

>TTHERM_00859260(protein)
MNKEIVYLQYEMDWLLGCLFNRLIETQKTINFFLSQFLLFFHSINKYLFFFETIKKIYIF
LFVCFFRLFLDLHLYVFLIYIKKQILWEKIYKVNLINYYQKLKNKKQKTNQFSKMTFSAT
DLPTLEKHLAAHTYLSGTDKPAKIDAQIATELKDKKVALNAATHPNVYAWFSFIGLFTPE
AQNTWADVAPVAVPVAAKKEAKKETKTDDVDLFGDDDEEDAEAEALREKKRLEAVAAKEA
RDGKKKKAIAKTILVFNVKVFEAEQDLDALAKKIYETIQLDGLVWNKEHKKIPVAFGVFM
LQMGCIIEDDKVNTDSIFEPIQSWEDEVQSVDVETMQKL

>TTHERM_00859260(gene)
ATGAATAAAGAAATAGTATATTTATAATATGAGATGGATTGGTTGCTTGGTTGCTTGTTT
AATAGATTGATAGAAACTTAAAAAACTATAAATTTCTTTTTAAGTCAATTCCTTCTTTTT
TTCCATTCGATAAACAAATATCTTTTTTTTTTTGAGACAATCAAAAAAATATATATATTT
TTGTTTGTTTGCTTTTTTAGATTATTTTTAGATTTGCATTTGTACGTATTTTTAATATAC
ATTAAAAAATAAATTCTCTGGGAAAAGATATATAAAGTAAATTTAATAAATTATTATCAA
AAACTAAAAAACAAAAAGCAAAAAACAAACCAATTCTCTAAAATGACTTTCTCTGCTACC
GACCTCCCCACCCTCGAAAAGCACTTAGCTGCCCACACCTACCTTTCCGGTACTGATAAG
CCCGCTAAGATTGATGCTTAAATTGCCACCGAACTCAAGGGTAACTTATTTATTTACTAA
TCATTATCTCCCTCACATCCATCCATCCATTCACTTACTTACTCATTCACTCATTATTCG
GTGATCTCTTCCACTTAGACTTTTTTCTCTTAGAAAATTTTAAAATAATGGATTGAAGAA
AATAAACTTCTTTGAAATTTTTTAGTCAATATTGCTCTCTTAAAACACACTCAAGTTTTC
ATTAATAATTTATTAATATTATTTTAAATATATAGATAAGAAGGTTGCCCTCAACGCCGC
CACCCACCCCAACGTCTATGCCTGGTTCAGCTTCATCGGTTTATTCACCCCCGAAGCTCA
AAATACCTGGGCTGATGTTGCTCCCGTCGCCGTCCCCGTTGCTGCCAAGAAGGAAGCCAA
GAAGGAAACCAAGACCGTAAGAAATTTTTCTTTTATCAAGCAATAACAACAATGGAAATC
ATTTTAATTCTACCCATAACTCCTATAGCTTATTTACTTACTAACTTACAAAAGATAAAA
TGAATAAAAATAAATTTTCTTGATATATAAATAAATACCTATTCCCCCTTTGATATATAT
ATCGGAAAACATGCAAGCGACAAGCAAAGATAGGATTTTCATTGACCATAGAACCATTTT
TCTAAATTATTGTTGTATATAAATAGGACGATGTCGATCTTTTCGGTGATGATGATGAAG
AAGATGCTGAAGCTGAAGCTTTGAGAGAAAAGAAGAGACTCGAAGCCGTCGCTGCCAAGG
AAGCTAGAGATGGTAAGAAGAAGAAGGCTATTGCCAAGACTATCCTCGTCTTCAACGTCA
AGGTCTTCGAAGCTGAATAAGACTTAGACGCTTTGGCCAAGAAGATCTACGAAACCATCC
AACTCGACGGTTTGGTCTGGAACAAGGAACACAAGAAGATCCCCGTTGCCTTCGGTGTCT
TCATGCTCCAAATGGGTTGCATCATTGAAGACGATAAGGTCAACACCGACAGTATCTTCG
AACCCATCCAATCTTGGGAAGATGAAGTCCAATCCGTTGATGTTGAAACCATGCAAAAAC
TTTGA