Identifiers and Description

Gene Model Identifier

TTHERM_00616050

Standard Name

DRS1 (Aspartyl-tRNA synthetase 1)

Aliases

PreTt19154 | 85.m00147 | 3725.m00038

Description

DRS1 aspartyl-tRNA synthetase protein; aspartyl-tRNA synthetase family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cytoplasm (IEA) | GO:0005737

Molecular Function

• aminoacyl-tRNA ligase activity (IEA) | GO:0004812
• nucleic acid binding (IEA) | GO:0003676
• nucleotide binding (IEA) | GO:0000166
• ATP binding (IEA) | GO:0005524

Biological Process

• tRNA aminoacylation for protein translation (IEA) | GO:0006418
• translation (IEA) | GO:0006412

Domains

• ( TIGR00499 ) lysyl-tRNA synthetase
• ( TIGR00458 ) aspartyl-tRNA synthetase
• ( TIGR00459 ) aspartyl-tRNA synthetase
• ( TIGR00457 ) asparaginyl-tRNA synthetase
• ( PF01336 ) OB-fold nucleic acid binding domain
• ( PF00152 ) tRNA synthetases class II (D,
• ( TIGR00462 ) lysyl-tRNA synthetase-like protein GenX
• ( PF00587 ) tRNA synthetase class II core

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.6%

TetraMine Data

TTHERM_00616050

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Stentor Coeruleus	SteCoe_27181	0
Tetrahymena borealis	EI9_18334.1	9.997093137033517e-262	aspartyl-tRNA synthetase (631 aa)
Oxytricha	Contig8290.0.g58	9.997093137033517e-262	tRNA synthetases class II (D, K and N)
SGD	YLL018C	9.00303245425055e-177	DPS1 Aspartyl-tRNA synthetase, primarily cytoplasmic; homodi meric enzyme that catalyzes th e specific aspartylation of tR NA(Asp); class II aminoacyl tR NA synthetase; binding to its own mRNA may confer autoregula tion
DictyBase	DDB_G0272236	3.999622461503957e-161	aspS1 on chromosome: 2 positio n 1722204 to 1724012
WormBase	WBGene00001094	6.002643599093603e-161	locus:dars-1 Aspartate--tRNA ligase, cytoplasmic status: Confirmed UniProt:Q03577 p rotein_id:CAA79536.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00616050(coding)
ATGGCTGATAAAGTTGAAACCCCCGTTGTTGAAAAACAAGAAGAAACTGTCCCTGTTGAA
GGAGCTGCTAAGGAAGGTGGTGAAAATGCTTCTAAGAAAGCTCAAAAGAAGCTTGAAAAG
GAACAAGAAAAGGAAAGAAAGAGATTAGAAAGAGAAGCCGCCTAATTGAAGGAATAGGAG
GAAAATTGGCTTAAGGAACTCAAGGAAGATACTCTTAAGGAAAACTACGGAGATTATATC
CTTGTTCAAAGTCAAGAAAAGACTGACAGAAAGTGGATTTAGGTTTTGAGTATTGATGAA
TCAATGGTCGGTTAAACCGTCTTGATCAGAGCAAGACTCCAAAATTCTAGAGTTAAGGGT
AATGTCGGTTTCTTAGTTTTGAGATAACAATTTTCTACCATCCAAGCTATGATCTCTAAG
AACGACGTCACTGTTTCTAAGACCATGGTTAAATGGGTTGGTAAGGTTCCTTGTGAATCT
ATCGTTGATGTTTACGGTGTTGTCTCTAAGCCTGAAACTGAAATTAAGAGTACTTCATGC
AAACTTGAATTGATTGTCAACAAGGTTTATGTTGTCTCTCGTTCAAGAGCTCAACTTCCT
TTCCAATTAGAAGATGCTGCTAGATAATAAAAGAAGGAAGAACAATTAGCTGAATACAAT
AACAATGAAGGTGATATTGAAGAATCTAAGGATAATTAAGCCAGTGTCTCCATTAAAACT
CGTTTAGATAACAGAATTATTGATTTAAGAACTCCTGCCAAGCAAGCTATTTTCAGATTA
CAATCTGGTATCTGCCAATTATTCCGTGAATACTTACTTTCATAAGATTTCGTTGAAATT
CACACTCCTAAGCTTATTGGTGGTTCTTCTGAAGGTGGTGCTAACATCTTCAAGTTGAAG
TATTTCGATAAGGATGCTTGTCTTGCTTAATCTCCTTAACTCTACAAGTAAATGTGTATC
TAATCTGACTTCGAAAGAGTCTTCGAAATAGGTCCCGTTTTCAGAGCTGAAAAATCATTC
ACCCATCGTCACATGTGTGAATTCACTGGTTTGGATATTGAAATGTCCATTAAAGAAAAC
TACCATGAGCTTCTTGATCTTATGGGTGATTTATTCGTCCACATCTTCAAGGGCTTAGAA
ACCAAATACAGCAAGGAAATCGAAGCTATTTAATAATAATTCCCCTTCGAACCTTTCAAA
ATTAAAACCCCTGTTGTTAAACTCACTTTCGAAGAAGGTTGCAAACTCTTAAAAGAAGCT
GGTATTGAATAAAACCCCTTAGAAGATTTAGATACTGTTACTGAAAAGAAGCTTGGTGAC
ATCGTCCGTGAAAAGTATGATACTGATTTCTATATGCTCCATAGATATCCTATCTCTGCT
AGACCTTTCTACACCATGCTTTGCCACGATGATCCTAACTACACTCTTTCTTACGATTTC
TTCATGAGAGGTTAAGAAATCACCTCAGGTGCCTAAAGAAATCACGACCCCGTTTCTCTC
GCTAAGCGTGCTGCTGAATGTGGTATCAATGTAGAAACTATTAAAGATTATATTGAATCT
ATGGCTTTCGGTGCTTATCCTCATGGTGGTTGTGGTATTGGTCTTGAAAGAGTTGTTTTC
CTCTACTGCGACCTTTACGATATTAGAAACGGTTGCTTATTCCCCAGAGATCCTAAAAGA
ATTGCTCCTTGA

>TTHERM_00616050(protein)
MADKVETPVVEKQEETVPVEGAAKEGGENASKKAQKKLEKEQEKERKRLEREAAQLKEQE
ENWLKELKEDTLKENYGDYILVQSQEKTDRKWIQVLSIDESMVGQTVLIRARLQNSRVKG
NVGFLVLRQQFSTIQAMISKNDVTVSKTMVKWVGKVPCESIVDVYGVVSKPETEIKSTSC
KLELIVNKVYVVSRSRAQLPFQLEDAARQQKKEEQLAEYNNNEGDIEESKDNQASVSIKT
RLDNRIIDLRTPAKQAIFRLQSGICQLFREYLLSQDFVEIHTPKLIGGSSEGGANIFKLK
YFDKDACLAQSPQLYKQMCIQSDFERVFEIGPVFRAEKSFTHRHMCEFTGLDIEMSIKEN
YHELLDLMGDLFVHIFKGLETKYSKEIEAIQQQFPFEPFKIKTPVVKLTFEEGCKLLKEA
GIEQNPLEDLDTVTEKKLGDIVREKYDTDFYMLHRYPISARPFYTMLCHDDPNYTLSYDF
FMRGQEITSGAQRNHDPVSLAKRAAECGINVETIKDYIESMAFGAYPHGGCGIGLERVVF
LYCDLYDIRNGCLFPRDPKRIAP

>TTHERM_00616050(gene)
ATGGCTGATAAAGTTGAAACCCCCGTTGTTGAAAAACAAGAAGAAACTGTCCCTGTTGAA
GGAGCTGCTAAGGAAGGTGGTGAAAATGCTTCTAAGAAAGCTCAAAAGAAGCTTGAAAAG
GAACAAGAAAAGGAAAGAAAGAGATTAGAAAGAGAAGCCGCCTAATTGAAGGAATAGGAG
GAAAATTGGCTTAAGGAACTCAAGGAAGATACTCTTAAGGAAAACTACGGAGATTATATC
CTTGTTCAAAGTCAAGAAAAGACTGACAGAAAGTGGATTTAGGTATTTACTCATTCCTTA
TTACTTTATTTCATATTTTTAAAAGCTCATTTTCAACAACAAAAGTTCAAGTTTTTGTAT
CTTCTTTTGTAGCGCCACAAGCATAAACATAAAAAAGAGAAATACAATCAAATGAGTAAT
AAAAAATAGAAATGCATCAAGAAATTTTAGAAACTAATCTATAAATGCAAACATTTTATC
ATTTTATTAATAACTTTTATTTCTATAATGAATAGGTTTTGAGTATTGATGAATCAATGG
TCGGTTAAACCGTCTTGATCAGAGCAAGACTCCAAAATTCTAGAGTTAAGGGTAATGTCG
GTTTCTTAGTTTTGAGATAACAATTTTCTACCATCCAAGCTATGATCTCTAAGAACGACG
TCACTGTTTCTAAGACCATGGTTAAATGGGTTGGTAAGGTTCCTTGTGAATCTATCGTTG
ATGTTTACGGTGTTGTCTCTAAGCCTGAAACTGAAATTAAGAGTACTTCATGCAAACTTG
AATTGATTGTCAACAAGGTTTATGTTGTCTCTCGTTCAAGAGCTCAACTTCCTTTCCAAT
TAGAAGATGCTGCTAGATAATAAAAGAAGGAAGAACAATTAGCTGAATACAATAACAATG
AAGGTGATATTGAAGAATCTAAGGATAATTAAGCCAGTGTCTCCATTAAAACTCGTTTAG
ATAACAGAATTATTGATTTAAGAACTCCTGCCAAGCAAGCTATTTTCAGATTACAATCTG
GTATCTGCCAATTATTCCGTGAATACTTACTTTCATAAGATTTCGTTGAAATTCACACTC
CTAAGCTTATTGGTGGTTCTTCTGAAGGTGGTGCTAACATCTTCAAGTTGAAGTATTTCG
ATAAGGATGCTTGTCTTGCTTAATCTCCTTAACTCTACAAGTAAATGTGTATCTAATCTG
ACTTCGAAAGAGTCTTCGAAATAGGTCCCGTTTTCAGAGCTGAAAAATCATTCACCCATC
GTCACATGTGTGAATTCACTGGTTTGGATATTGAAATGTCCATTAAAGAAAACTACCATG
AGCTTCTTGATCTTATGGGTGATTTATTCGTCCACATCTTCAAGGGCTTAGAAACCAAAT
ACAGCAAGGAAATCGAAGCTATTTAATAATAATTCCCCTTCGAACCTTTCAAAATTAAAA
CCCCTGTTGTTAAACTCACTTTCGAAGAAGGTTGCAAACTCTTAAAAGAAGCTGGTATTG
AATAAAACCCCTTAGAAGATTTAGATACTGTTACTGAAAAGAAGCTTGGTGACATCGTCC
GTGAAAAGTATGATACTGATTTCTATATGCTCCATAGATATCCTATCTCTGCTAGACCTT
TCTACACCATGCTTTGCCACGATGATCCTAACTACACTCTTTCTTACGATTTCTTCATGA
GAGGTTAAGAAATCACCTCAGGTGCCTAAAGAAATCACGACCCCGTTTCTCTCGCTAAGC
GTGCTGCTGAATGTGGTATCAATGTAGAAACTATTAAAGATTATATTGAATCTATGGCTT
TCGGTGCTTATCCTCATGGTGGTTGTGGTATTGGTCTTGAAAGAGTTGTTTTCCTCTACT
GCGACCTTTACGATATTAGAAACGGTTGCTTATTCCCCAGAGATCCTAAAAGAATTGCTC
CTTGA