Identifiers and Description

Gene Model Identifier

TTHERM_01194810

Standard Name

DRP6 (Dynamin Related Protein)

Aliases

PreTt07518 | 270.m00044

Description

Dynamin-related protein; localized to cytoplasmic face of the nuclear envelope

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• nuclear envelope (IDA) | GO:0005635 | Ref:16276403

Molecular Function

• GTPase activity (IEA) | GO:0003924
• GTP binding (IEA) | GO:0005525

Domains

• ( PF00350 ) Dynamin family
• ( PF08477 ) Miro-like protein
• ( PF01031 ) Dynamin central region
• ( PF01926 ) GTPase of unknown function
• ( PF02212 ) Dynamin GTPase effector domain
• ( TIGR00072 ) hydrogenase maturation protease

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.8%

TetraMine Data

TTHERM_01194810

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_21014.1	9.997316819378982e-180	dynamin central region family protein (506 aa)
Oxytricha	Contig22482.0.g88	4.0007753645635287e-88	Dynamin central region
DictyBase	DDB_G0277849	1.9997677415930956e-65	dymA on chromosome: 3 position 252381 to 255025
SGD	YKR001C	3.9982663658145016e-63	VPS1 Dynamin-like GTPase requi red for vacuolar sorting; also involved in actin cytoskeleto n organization, endocytosis, l ate Golgi-retention of some pr oteins, regulation of peroxiso me biogenesis
WormBase	WBGene00001130	9.004195835458823e-61	locus:dyn-1 Dynamin status :Confirmed UniProt:P39055 protein_id:CAB01857.1
Stentor Coeruleus	SteCoe_5951	2.4426007377405277e-36

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16276403: Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP (2005) Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. PLoS genetics 1(5):e52

Sequences

>TTHERM_01194810(coding)
ATGACTAATACAATCGTACCTGCTAATAACTTTCAAAATATCAAAGAAGTTATCAAAGTT
GTAAATAAGCTTAGAGATTTTGGAATTGAGTCTGATAAGATATAGCTTCCAAAAATTGTT
GTCATTGGTGTTTAATCTTCTGGTAAATCTTCGCTTCTTGAATAAATTGTACAACTAGAT
TTTTTACCTAGAGGAACTGGAGTTGTCACTCGTTGCCCTTTAGAAATAAGACTCATAGAA
GTTACTAATTAAGACAGTGATTTTAAGCCTTACGCTTACTTTTTCGAAGAGAGGTAAAAA
ATCTTTCATGATTTTGAACTAGTGAAAAAAGAGATTCAAAAGATTACAAATGATTTTGCT
GGTCCAGGTAAAAAAATAGTAGATAAAGTTATTACTTTAACTATCTATTAGGCCTAATGT
CCTACTTTGACTTTAATCGATTTGCCTGGTATGACTTTAAATTCTGTAGGTGACTAGAAA
GATATTGAAAGAGTTACATAAGATATGACTAAAAAGTATATCATTGAAAAAACAACAATC
ATTCTTTGCGTTATTCCAATTAATTAAGATTTGGAAAACTCACTTGCTTTAAATCTTGCT
AGATCTGTAGATGAAAATGGAGAACGTACTATTGGTGTTCTTACTATGATTGATATAATG
AATCCTGGTACAAACTGTGAGAATGTGTTGAAAAATAGATAAATTCCCCTTTTGCATAGG
TATTACGGTATGAAACCTCGTAGCTAAAAAGACATCAACGAAAATGTTTCAGTATAAGAA
GCAATCTAAAGAGAATAATTATATTTCACTTCACATTAAATTTATTCGATGTATCCTGAG
TACACAGGTACAAATGCTTTAACTAATAAGTTATCAACTTTGTTAGACAGTCATATTCGT
ACTTTCTTACCTTCAATCCATAAAAAAATAAAGATGACCCTTTCTGAAAGAATAAAAGAA
AGATAACAATTGGGAAATGAGTTTCCTACTGAAGTTACTTAGTAACTATATGAACTAACA
AATATTATTAACACATCCTTGAATTTATTTAAGCAAGCAATGACTAACTATGACGCTAGC
GAAATTCAGAATATCGGTAAGATTAAAGTTGATGAAAGAGTTGGTAAAAGTTATGCAGAC
TTTCTGTTTGATAAGTATTTATTAATTTGTAAAAAAATATCTGAAGAATAAGTTTTTAAG
GTTAAAATGAAAGACCTTATCAAGGAGCTAGGAAAATTTAGAGTTCAAGTTAATGGATTC
CTTCCTTTTGAAGTTTTTGAATCTTAAATAAAGCAAAAAATAAATTTATATGAAACAGAG
GCTATAGTAATTTTAGAGTAGCTGAAAGAGCATGTAAGGAAAGTATTAAATCATTGCATA
GATTTATTTCCTTTCCCAAACAATAAAATAAAGAAAATAATGTAGGATATACTTTAAAAC
TTTGTATAAACAGAATATAATTTCACATCATCTCACATAAAAACTGCATTTTATTGCTAC
AAAGATTGTATTTGTTCAAAAATGATAGATATTCATGAGACTGAATCTAAATTGAAATAA
AATCACGTATACCTGCAGAATGATAACCAATAGAAAAAAGTTTTATATGAGTATATTTCT
AAAAATAAATCATTTATGGAATGGACTGTTTAAGAAATAATGATAAAAGCAGAAAATTTA
TGTAATGTTCCTATTACTATGAGTGATTTATAGAATACTTACACAAAGGCAGAAGAAAAA
GTATAAAACACAGATGAAGTTTTGAGATATTCAATTATTTATTATAAATACATGGATAAT
TTTAGAAAATAAATCAGTGATCAAATTCCATAGTGTATTCAATCTTTATTCATTAATAGC
CTTTGTAAGAATCTCATGGTAAAAGTTTTCTAAGCTATTTAGAGCAAAGAATACAAAGAA
ATTATAGAAAAAAACCTAAAAGAAGATGAAATAATTGCAACTAAAAGAGCAAAGGTAATT
TAATCTATCTAAAAATTAGCTAAAGCAAACGATAGGCTGGAACGTTTAATCGATTAAGGC
TAAAATTGCAATCACATGCTATCCACAACTTATGGTGATGAAGAAAATTATATTCACGAG
TCTTTAGAAGACTCTGATGGTATTGATGATTGA

>TTHERM_01194810(protein)
MTNTIVPANNFQNIKEVIKVVNKLRDFGIESDKIQLPKIVVIGVQSSGKSSLLEQIVQLD
FLPRGTGVVTRCPLEIRLIEVTNQDSDFKPYAYFFEERQKIFHDFELVKKEIQKITNDFA
GPGKKIVDKVITLTIYQAQCPTLTLIDLPGMTLNSVGDQKDIERVTQDMTKKYIIEKTTI
ILCVIPINQDLENSLALNLARSVDENGERTIGVLTMIDIMNPGTNCENVLKNRQIPLLHR
YYGMKPRSQKDINENVSVQEAIQREQLYFTSHQIYSMYPEYTGTNALTNKLSTLLDSHIR
TFLPSIHKKIKMTLSERIKERQQLGNEFPTEVTQQLYELTNIINTSLNLFKQAMTNYDAS
EIQNIGKIKVDERVGKSYADFLFDKYLLICKKISEEQVFKVKMKDLIKELGKFRVQVNGF
LPFEVFESQIKQKINLYETEAIVILEQLKEHVRKVLNHCIDLFPFPNNKIKKIMQDILQN
FVQTEYNFTSSHIKTAFYCYKDCICSKMIDIHETESKLKQNHVYLQNDNQQKKVLYEYIS
KNKSFMEWTVQEIMIKAENLCNVPITMSDLQNTYTKAEEKVQNTDEVLRYSIIYYKYMDN
FRKQISDQIPQCIQSLFINSLCKNLMVKVFQAIQSKEYKEIIEKNLKEDEIIATKRAKVI
QSIQKLAKANDRLERLIDQGQNCNHMLSTTYGDEENYIHESLEDSDGIDD

>TTHERM_01194810(gene)
ATGACTAATACAATCGTACCTGCTAATAACTTTCAAAATATCAAAGAAGTTATCAAAGTT
GTAAATAAGCTTAGAGATTTTGGAATTGAGTCTGATAAGATATAGCTTCCAAAAATTGTT
GTCATTGGTGTTTAATCTTCTGGTAAATCTTCGCTTCTTGAATAAATTGTACAACTAGAT
TTTTTACCTAGAGGAACTGGAGTTGTCACTCGTTGCCCTTTAGAAATAAGACTCATAGAA
GTTACTAATTAAGACAGTGATTTTAAGCCTTACGCTTACTTTTTCGAAGAGAGGTAAAAA
ATCTTTCATGATTTTGAACTAGTGAAAAAAGAGATTCAAAAGATTACAAATGATTTTGCT
GGTCCAGGTAAAAAAATAGTAGATAAAGTTATTACTTTAACTATCTATTAGGCCTAATGT
CCTACTTTGACTTTAATCGATTTGCCTGGTATGACTTTAAATTCTGTAGGTGACTAGAAA
GATATTGAAAGAGTTACATAAGATATGACTAAAAAGTATATCATTGAAAAAACAACAATC
ATTCTTTGCGTTATTCCAATTAATTAAGATTTGGAAAACTCACTTGCTTTAAATCTTGCT
AGATCTGTAGATGAAAATGGAGAACGTACTATTGGTGTTCTTACTATGATTGATATAATG
AATCCTGGTACAAACTGTGAGAATGTGTTGAAAAATAGATAAATTCCCCTTTTGCATAGG
TATTACGGTATGAAACCTCGTAGCTAAAAAGACATCAACGAAAATGTTTCAGTATAAGAA
GCAATCTAAAGAGAATAATTATATTTCACTTCACATTAAATTTATTCGATGTATCCTGAG
TACACAGGTACAAATGCTTTAACTAATAAGTTATCAACTTTGTTAGACAGTCATATTCGT
ACTTTCTTACCTTCAATCCATAAAAAAATAAAGATGACCCTTTCTGAAAGAATAAAAGAA
AGATAACAATTGGGAAATGAGTTTCCTACTGAAGTTACTTAGTAACTATATGAACTAACA
AATATTATTAACACATCCTTGAATTTATTTAAGCAAGCAATGACTAACTATGACGCTAGC
GAAATTCAGAATATCGGTAAGATTAAAGTTGATGAAAGAGTTGGTAAAAGTTATGCAGAC
TTTCTGTTTGATAAGTATTTATTAATTTGTAAAAAAATATCTGAAGAATAAGTTTTTAAG
GTTAAAATGAAAGACCTTATCAAGGAGCTAGGAAAATTTAGAGTTCAAGTTAATGGATTC
CTTCCTTTTGAAGTTTTTGAATCTTAAATAAAGCAAAAAATAAATTTATATGAAACAGAG
GCTATAGTAATTTTAGAGTAGCTGAAAGAGCATGTAAGGAAAGTATTAAATCATTGCATA
GATTTATTTCCTTTCCCAAACAATAAAATAAAGAAAATAATGTAGGATATACTTTAAAAC
TTTGTATAAACAGAATATAATTTCACATCATCTCACATAAAAACTGCATTTTATTGCTAC
AAAGATTGTATTTGTTCAAAAATGATAGATATTCATGAGACTGAATCTAAATTGAAATAA
AATCACGTATACCTGCAGAATGATAACCAATAGAAAAAAGTTTTATATGAGTATATTTCT
AAAAATAAATCATTTATGGAATGGACTGTTTAAGAAATAATGATAAAAGCAGAAAATTTA
TGTAATGTTCCTATTACTATGAGTGATTTATAGAATACTTACACAAAGGCAGAAGAAAAA
GTATAAAACACAGATGAAGTTTTGAGATATTCAATTATTTATTATAAATACATGGATAAT
TTTAGAAAATAAATCAGTGATCAAATTCCATAGTGTATTCAATCTTTATTCATTAATAGC
CTTTGTAAGAATCTCATGGTAAAAGTTTTCTAAGCTATTTAGAGCAAAGAATACAAAGAA
ATTATAGAAAAAAACCTAAAAGAAGATGAAATAATTGCAACTAAAAGAGCAAAGGTAATT
TAATCTATCTAAAAATTAGCTAAAGCAAACGATAGGCTGGAACGTTTAATCGATTAAGGC
TAAAATTGCAATCACATGCTATCCACAACTTATGGTGATGAAGAAAATTATATTCACGAG
TCTTTAGAAGACTCTGATGGTATTGATGATTGA