Identifiers and Description

Gene Model Identifier

TTHERM_01194760

Standard Name

DRP4 (Dynamin Related Protein 4)

Aliases

PreTt07513 | 270.m00039

Description

DRP4 dynamin central region family protein; Dynamin central region family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cytoplasm (IDA) | GO:0005737 | Ref:16276403

Molecular Function

• GTPase activity (IEA) | GO:0003924
• GTP binding (IEA) | GO:0005525

Domains

• ( PF00350 ) Dynamin family
• ( PF08477 ) Miro-like protein
• ( PF01031 ) Dynamin central region
• ( PF01926 ) GTPase of unknown function
• ( PF02212 ) Dynamin GTPase effector domain
• ( TIGR00072 ) hydrogenase maturation protease
• ( PF08011 ) Protein of unknown function (DUF1703)

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.7%

TetraMine Data

TTHERM_01194760

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_21014.1	9.997093137033517e-262	dynamin central region family protein (506 aa)
Oxytricha	Contig22482.0.g88	7.996289531394984e-82	Dynamin central region
DictyBase	DDB_G0277849	1.0000310450948521e-65	dymA on chromosome: 3 position 252381 to 255025
SGD	YKR001C	5.997098480211051e-62	VPS1 Dynamin-like GTPase requi red for vacuolar sorting; also involved in actin cytoskeleto n organization, endocytosis, l ate Golgi-retention of some pr oteins, regulation of peroxiso me biogenesis
WormBase	WBGene00001130	9.996907204735647e-62	locus:dyn-1 Dynamin status :Confirmed UniProt:P39055 protein_id:CAB01857.1
Stentor Coeruleus	SteCoe_5951	4.4737793061811207e-38

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16276403: Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP (2005) Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. PLoS genetics 1(5):e52

Sequences

>TTHERM_01194760(coding)
ATGACAAGCAGTGTTTCTACAAATAGCTTTCAAAACATTAAAGAAGTTATCAAGGTTGTA
AATAATCTTAGAGATTTTGGAGTAGAATCTGATAAAATTGAGCTTCCTAAAATAGTAGTT
ATTGGTGTTTAATCTTCAGGTAAGTCTTCACTTCTAGAGTAAATTGTCTAGATAGACTTT
TTACCTAGAGGTACTGGAGTAGTGACTCGTTGTCCTTTAGAAATAAGACTCATTGAAGTA
ACCAGCTATGCTAAAGATTTTAAGCCCTACGCTTACTTTTTTGAAGAAAGAAGCAAAACA
TATGAAAATTTTGAAGAAGTAAAAAAAAGAATTGAAACAATTACAAAGGAGCAAGCTGGA
GTAGGTAAAAAGATTGTTGATCAAGCAATAACTTTGACTATCTTCTAGACTAAATGCCCT
ACTTTGACTTTAATTGATTTACCAGGTATGACTTTGAATTCTATCGAAGACTAGGTCGAT
GTTGAAAAAGTTACTCAAGACATGACTTTAAAATACATCAAAGAAGAAACTACAATTATC
CTTTGTGTTATTCCTATCAACTAGGATTTAGAAAACTCTCTTGCTTTGAAGCTTGCTAGA
AATGTTGATAAAACTGGTAGTCGTACTATTGGAGTACTTACTATGATAGATATAATGAAT
CCAGGCACAAATTGTGAGAAAGTGTTAAGAAATTAGTAAATTCCACTTAAGCATAGATAT
TATGGTATGAAACCTCGTAATTAAAATGATATAAATAACAATATCACAGTTGAATAAGCT
ATAAAAAATGAATAAGAATATTTTTCAAACCATGAAGTTTACAAAGAGTTTGCTGATTAT
ACTGGCACAGCTGCCTTAACTCATAAACTTTCTACATTATTAGATAGTCACATTCGTCAC
TTTTTGCCAGATATTTTTAAAAAGATCTATTCTACTCTTCTTTAAAGAATAGAGTCAAGA
AAAAAATTAGGCGATCCTTTCCCTACTGATATCAACAAATAGTAAAAAGAGCTGAGAGAT
ATAATTAACAAATCTTTAAATATTTTCAAACAAGCTATGTAAGACTTTGATTTAACTGAA
GTTGAAAATATTGAAAAAATCTAAGTTGGAGAAAGAATGGGTAGAAATTATGTTGACTTT
TTAATGGATCATTATTCAGAATAAAATAGAGAATTATTCATTCAATCTCTCAAAAATGTT
GATATGAAAAAAGTCTAGCACGAACTTTAGAAGTTTAGAATTCCTGTTAACGGATTTATT
CCTTTCTAGGCCCTCCAATCTTAGATAAGATAGCATGTAAGTCACTATGAGCACAAAGCC
AAGGAGTTGCTTGAAAGTATAAAGGAATATTTAAAGAAAGTACTATATTTCTGCATTGAT
TAGTATCCTTATCCTAACCACTTTATAAAGAAAATGATTTAAGATCTAGTTTCAAAGTAT
ATTACAAAAGAATTTAAATTAACTAAAGCTCATATCGAAACAACATTCAAATGCTATAAA
GAATCCATATATTCAACAACGATTGATGTTCATGGCTATGAAACTAATTTAAAGTAATCT
TTTGTTATTAATTCTTTGGTCGCTAATTAGAAAAAATCTGTTTATGAATATATTACTAAA
AACACAAATTTCATGAAATGGACTATTTTTGATATAATTCATAAATCAGAATAGCTGTCA
GGAAAAACCATTTCAAGCTCAGAATATAATGATGTTGTATTGAAGACTGACGAAAAATAC
AATACTGACGAAATTATGAGATATTCTATCATATTTTATTAATATTTGGAAAACTTTAGA
AAATAGATCAGTGATTAAATTCCATAATTCATATAGACTTTATTTATCAACAGTCTATGT
AATTCACTCTTCTTAAATGTTGTAAACGATATTTTCAGCAATGAATGCAAAGAAGCTATG
GAAAAAAATCTTAAAGAAGATGCTAGATTGACTGAAGAAAGAAAGATTGTAGCTTAATCT
CTCAAAAAGCTTAAAAAAGCTTACATAACACTTAAATCCCTATAAGAAAAAAGCTTTGAT
TACTATTCATCAAGCTCTGTAACTTGTGAAAGTGAAGATCTTGTTTTACATTTTGAATGT
GAAGACACCTATTATGATGATGAAGATGATGAAGATTCTATCACAACTGTGTTTTGA

>TTHERM_01194760(protein)
MTSSVSTNSFQNIKEVIKVVNNLRDFGVESDKIELPKIVVIGVQSSGKSSLLEQIVQIDF
LPRGTGVVTRCPLEIRLIEVTSYAKDFKPYAYFFEERSKTYENFEEVKKRIETITKEQAG
VGKKIVDQAITLTIFQTKCPTLTLIDLPGMTLNSIEDQVDVEKVTQDMTLKYIKEETTII
LCVIPINQDLENSLALKLARNVDKTGSRTIGVLTMIDIMNPGTNCEKVLRNQQIPLKHRY
YGMKPRNQNDINNNITVEQAIKNEQEYFSNHEVYKEFADYTGTAALTHKLSTLLDSHIRH
FLPDIFKKIYSTLLQRIESRKKLGDPFPTDINKQQKELRDIINKSLNIFKQAMQDFDLTE
VENIEKIQVGERMGRNYVDFLMDHYSEQNRELFIQSLKNVDMKKVQHELQKFRIPVNGFI
PFQALQSQIRQHVSHYEHKAKELLESIKEYLKKVLYFCIDQYPYPNHFIKKMIQDLVSKY
ITKEFKLTKAHIETTFKCYKESIYSTTIDVHGYETNLKQSFVINSLVANQKKSVYEYITK
NTNFMKWTIFDIIHKSEQLSGKTISSSEYNDVVLKTDEKYNTDEIMRYSIIFYQYLENFR
KQISDQIPQFIQTLFINSLCNSLFLNVVNDIFSNECKEAMEKNLKEDARLTEERKIVAQS
LKKLKKAYITLKSLQEKSFDYYSSSSVTCESEDLVLHFECEDTYYDDEDDEDSITTVF

>TTHERM_01194760(gene)
ATGACAAGCAGTGTTTCTACAAATAGCTTTCAAAACATTAAAGAAGTTATCAAGGTTGTA
AATAATCTTAGAGATTTTGGAGTAGAATCTGATAAAATTGAGCTTCCTAAAATAGTAGTT
ATTGGTGTTTAATCTTCAGGTAAGTCTTCACTTCTAGAGTAAATTGTCTAGATAGACTTT
TTACCTAGAGGTACTGGAGTAGTGACTCGTTGTCCTTTAGAAATAAGACTCATTGAAGTA
ACCAGCTATGCTAAAGATTTTAAGCCCTACGCTTACTTTTTTGAAGAAAGAAGCAAAACA
TATGAAAATTTTGAAGAAGTAAAAAAAAGAATTGAAACAATTACAAAGGAGCAAGCTGGA
GTAGGTAAAAAGATTGTTGATCAAGCAATAACTTTGACTATCTTCTAGACTAAATGCCCT
ACTTTGACTTTAATTGATTTACCAGGTATGACTTTGAATTCTATCGAAGACTAGGTCGAT
GTTGAAAAAGTTACTCAAGACATGACTTTAAAATACATCAAAGAAGAAACTACAATTATC
CTTTGTGTTATTCCTATCAACTAGGATTTAGAAAACTCTCTTGCTTTGAAGCTTGCTAGA
AATGTTGATAAAACTGGTAGTCGTACTATTGGAGTACTTACTATGATAGATATAATGAAT
CCAGGCACAAATTGTGAGAAAGTGTTAAGAAATTAGTAAATTCCACTTAAGCATAGATAT
TATGGTATGAAACCTCGTAATTAAAATGATATAAATAACAATATCACAGTTGAATAAGCT
ATAAAAAATGAATAAGAATATTTTTCAAACCATGAAGTTTACAAAGAGTTTGCTGATTAT
ACTGGCACAGCTGCCTTAACTCATAAACTTTCTACATTATTAGATAGTCACATTCGTCAC
TTTTTGCCAGATATTTTTAAAAAGATCTATTCTACTCTTCTTTAAAGAATAGAGTCAAGA
AAAAAATTAGGCGATCCTTTCCCTACTGATATCAACAAATAGTAAAAAGAGCTGAGAGAT
ATAATTAACAAATCTTTAAATATTTTCAAACAAGCTATGTAAGACTTTGATTTAACTGAA
GTTGAAAATATTGAAAAAATCTAAGTTGGAGAAAGAATGGGTAGAAATTATGTTGACTTT
TTAATGGATCATTATTCAGAATAAAATAGAGAATTATTCATTCAATCTCTCAAAAATGTT
GATATGAAAAAAGTCTAGCACGAACTTTAGAAGTTTAGAATTCCTGTTAACGGATTTATT
CCTTTCTAGGCCCTCCAATCTTAGATAAGATAGCATGTAAGTCACTATGAGCACAAAGCC
AAGGAGTTGCTTGAAAGTATAAAGGAATATTTAAAGAAAGTACTATATTTCTGCATTGAT
TAGTATCCTTATCCTAACCACTTTATAAAGAAAATGATTTAAGATCTAGTTTCAAAGTAT
ATTACAAAAGAATTTAAATTAACTAAAGCTCATATCGAAACAACATTCAAATGCTATAAA
GAATCCATATATTCAACAACGATTGATGTTCATGGCTATGAAACTAATTTAAAGTAATCT
TTTGTTATTAATTCTTTGGTCGCTAATTAGAAAAAATCTGTTTATGAATATATTACTAAA
AACACAAATTTCATGAAATGGACTATTTTTGATATAATTCATAAATCAGAATAGCTGTCA
GGAAAAACCATTTCAAGCTCAGAATATAATGATGTTGTATTGAAGACTGACGAAAAATAC
AATACTGACGAAATTATGAGATATTCTATCATATTTTATTAATATTTGGAAAACTTTAGA
AAATAGATCAGTGATTAAATTCCATAATTCATATAGACTTTATTTATCAACAGTCTATGT
AATTCACTCTTCTTAAATGTTGTAAACGATATTTTCAGCAATGAATGCAAAGAAGCTATG
GAAAAAAATCTTAAAGAAGATGCTAGATTGACTGAAGAAAGAAAGATTGTAGCTTAATCT
CTCAAAAAGCTTAAAAAAGCTTACATAACACTTAAATCCCTATAAGAAAAAAGCTTTGAT
TACTATTCATCAAGCTCTGTAACTTGTGAAAGTGAAGATCTTGTTTTACATTTTGAATGT
GAAGACACCTATTATGATGATGAAGATGATGAAGATTCTATCACAACTGTGTTTTGA