Identifiers and Description

Gene Model Identifier

TTHERM_00052190

Standard Name

CTH1 (Cathepsin-1 ( Cathepsin D))

Aliases

PreTt11399 | 3.m01858 | 3824.m03154

Description

Eukaryotic aspartyl protease family protein.

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• aspartic-type endopeptidase activity (IEA) | GO:0004190

Biological Process

• proteolysis (IEA) | GO:0006508

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 47.6%

TetraMine Data

TTHERM_00052190

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_01548.1	9.997093137033517e-262	eukaryotic aspartyl protease ( 460 aa)
DictyBase	DDB_G0279411	9.996696112986116e-50	ctsD on chromosome: 3 position 2104523 to 2105867
WormBase	WBGene00000217	3.998777993244535e-41	locus:asp-4 status:Confirmed UniProt:Q21966 protein_id :CAA90633.1
Oxytricha	Contig18588.0.g110	1.999002769139511e-37	Eukaryotic aspartyl protease
SGD	YPL154C	9.997975313387782e-28	PEP4 Vacuolar aspartyl proteas e (proteinase A), required for the posttranslational precurs or maturation of vacuolar prot einases; important for protein turnover after oxidative dama ge; synthesized as a zymogen, self-activates
Stentor Coeruleus	SteCoe_11715	2.3802664086944007e-26

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00052190(coding)
ATGATTAAGTTCAAGAATAAATTAAACTTTGTATTGATTGGTTTGATTCTCATTTTTTAT
TTGATTGGAATTGTAGAATCAAAAAATAACAATGGGAAGCATAAAACTCAAAAATCTTTC
ATTTAGTAGAAGAATGTCTTAAAAAAAAAAATTTACTCAATTCCTTTAACTAAAAAGCTT
CCCTCATAAGAATATCAAATCGAGACTCTAAATATTTTGAAAGAGCATCAAGCTTTACTT
TTGTAAATGAAAACATTTTCTTATTTAGAAATGGATTCTAATAAGCAAATAGTAAAAAAA
TAAAAGCAATTCAACAGTTTTTTGCAAACAGATTTGAAAATGCTAAAATAAAAGCAATCT
TTAGAGCTTAGAAATAGAGATAATTCTTTTTTTACTGGAAGAATAGAAGTAGGAAAATAG
CCTTTTGATGTTATTTTCGATACTGGAAGTGCTTTTGTTTTTATAAATAGCGACTATTGT
GCAGAATGCATGCAAGATCATCACTATTACACTGAAACAAAAACTTTGGAAGAAACTAAT
TTAGACATCACTGTTTAATTTGGTACTGGTTAGTTATCAGGTCTTTTAAGCAAAGATATA
ATAAGTCTAGGAGAAATAGAATTAGAAAAAGGTGTTTTCGCATAGATTACTTAGCAAGAT
GGAAGCTTATTTAAATCTCATTTTGATGGTATTGTTGGTTTATCTGCCCTAGATTTATCT
GAAGAATCCCCTTCTTTACTATCATAATTAAATAATTCTGGACAACTAGAACATAATGTA
GTTTCATTCTTCTTAGAAAGAGACGAAACTGGTTCTTAAATAATTCTAGGAGGAGTAGAC
AAAGACAAATATGATGGTGAAATTTAGTACCATCCAAGAATTGATGAGACTAATTTTTGG
ACTCTCCCTTGCAAATAAATTAAGGTTGGTAATGAGGATACAGGTTTATGCTCTGAAAGC
AACATTTGCAGATTAATTGTAGACTCTGGTACTTCTTTGTTCACTGGTCCTCATGATTCA
GTTGCAGTTCTCTTGAATAAGTTAAATAAAAATGAAGAAGGTTGTAAAAATTTGTATGAT
TTGCCTACAATTACCTTTGTTGTTGAAGACTCTGAATACACAGTTTATCCTAATGAATAC
ATAATAACTTCTACAATCACCCATAGCGATCCTTTTTATGAGCATTCAGATATTGATATA
ATAGTTGAGTGCATGGTTTCATTTTATGGGCTTTAAGTTAATGATCAAGGAGAAAGTTAA
AATACTTGGATTCTTGGAGATGTTTTTATGGGTAAATATTATACTGTTTTTGATAGTGAA
AATAAAAGAATAGGATTAGCTAAATCTATAAACTATGCATCTTATATTCACTGA

>TTHERM_00052190(protein)
MIKFKNKLNFVLIGLILIFYLIGIVESKNNNGKHKTQKSFIQQKNVLKKKIYSIPLTKKL
PSQEYQIETLNILKEHQALLLQMKTFSYLEMDSNKQIVKKQKQFNSFLQTDLKMLKQKQS
LELRNRDNSFFTGRIEVGKQPFDVIFDTGSAFVFINSDYCAECMQDHHYYTETKTLEETN
LDITVQFGTGQLSGLLSKDIISLGEIELEKGVFAQITQQDGSLFKSHFDGIVGLSALDLS
EESPSLLSQLNNSGQLEHNVVSFFLERDETGSQIILGGVDKDKYDGEIQYHPRIDETNFW
TLPCKQIKVGNEDTGLCSESNICRLIVDSGTSLFTGPHDSVAVLLNKLNKNEEGCKNLYD
LPTITFVVEDSEYTVYPNEYIITSTITHSDPFYEHSDIDIIVECMVSFYGLQVNDQGESQ
NTWILGDVFMGKYYTVFDSENKRIGLAKSINYASYIH

>TTHERM_00052190(gene)
ATGATTAAGTTCAAGAATAAATTAAACTTTGTATTGATTGGTTTGATTCTCATTTTTTAT
TTGATTGGAATTGTAGAATCAAAAAATAACAATGGGAAGCATAAAACTCAAAAATCTTTC
ATTTAGTAGAAGAATGTCTTAAAAAAAAAAATTTACTCAATTCCTTTAACTAAAAAGCTT
CCCTCATAAGAATATCAAATCGAGACTCTAAATATTTTGAAAGAGCATCAAGCTTTACTT
TTGTAAATGAAAACATTTTCTTATTTAGAAATGGATTCTAATAAGCAAATAGTAAAAAAA
TAAAAGCAATTCAACAGTTTTTTGCAAACAGATTTGAAAATGCTAAAATAAAAGCAATCT
TTAGAGCTTAGAAATAGAGATAATTCTTTTTTTACTGGAAGAATAGAAGTAGGAAAATAG
CCTTTTGATGTTATTTTCGATACTGGAAGTGCTTTTGTTTTTATAAATAGCGACTATTGT
GCAGAATGCATGCAAGATCATCACTATTACACTGAAACAAAAACTTTGGAAGAAACTAAT
TTAGACATCACTGTTTAATTTGGTACTGGTTAGTTATCAGGTCTTTTAAGCAAAGATATA
ATAAGTCTAGGAGAAATAGAATTAGAAAAAGGTGTTTTCGCATAGATTACTTAGCAAGAT
GGAAGCTTATTTAAAGTAATACTTTAAAGTTTCAATACTAAATTTATGAATATTCAATTA
TTAAATATATTCAAAATATTTAGTTTTGTAATAAATTTTAAAAATATATAATTAGTCTCA
TTTTGATGGTATTGTTGGTTTATCTGCCCTAGATTTATCTGAAGAATCCCCTTCTTTACT
ATCATAATTAAATAATTCTGGACAACTAGAACATAATGTAGTTTCATTCTTCTTAGAAAG
AGACGAAACTGGTTCTTAAATAATTCTAGGAGGAGTAGACAAAGACAAATATGATGGTGA
AATTTAGTACCATCCAAGAATTGATGAGACTAATTTTTGGACTCTCCCTTGCAAATAAAT
TAAGGTTGGTAATGAGGATACAGGTTTATGCTCTGAAAGCAACATTTGCAGATTAATTGT
AGACTCTGGTACTTCTTTGTTCACTGGTCCTCATGATTCAGTTGCAGTTCTCTTGAGTAA
ATAAATTAATATATTTCTTTCTTTCTTATATTTATAATATTTTAATTTAGATAAGTTAAA
TAAAAATGAAGAAGGTTGTAAAAATTTGTATGATTTGCCTACAATTACGTAAACAATAAA
AATCAATTAAAATATTTAAATTAACCTCATTTTATGAAAAAAGCTTTGTTGTTGAAGACT
CTGAATACACAGTTTATCCTAATGAATACATAATAACTTCTACAATCACCCATAGCGATC
CTTTTTATGAGCATTCAGATATTGATATAATAGTTGAGTGCATGGTTTCATTTTATGGGC
TTTAAGTTAATGATCAAGGAGGTAATTATTTCATTTATTCTTTAAAAATTTTAAAATAAA
AACTAATTATTTATTAAATTAATTTCAATTTTTATTCTCTATTCTAATTTAGAAAGTTAA
AATACTTGGATTCTTGGAGATGTTTTTATGGGTAAATATTATACTGTTTTTGATAGTGAA
AATAAAAGAATAGGATTAGCTAAATCTATAAACTATGCATCTTATATTCACTGA