Identifiers and Description

Gene Model Identifier

TTHERM_00283330

Standard Name

CET1

Aliases

PreTt04872 | 25.m00336 | p138 | 3694.m00119 | Spt16

Description

Protein associated with macronulear microtubules; sequence similarity to human transcription elongation factor FACT 140 kDa subunit, yeast Spt16/Cdc68, and Xenopus DUF140

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• FACT complex (ISS) | GO:0035101 | Ref:15013445
• macronucleus (IDA) | GO:0031039 | Ref:15013445

Molecular Function

• chromatin binding (IDA) | GO:0003682 | Ref:15013445
• protein heterodimerization activity (ISS) | GO:0046982 | Ref:15013445
• microtubule binding (IDA) | GO:0008017 | Ref:15013445

Domains

• ( PF02016 ) LD-carboxypeptidase
• ( PF00557 ) peptidase, M24 family
• ( PF08512 ) Histone chaperone Rttp106-like
• ( PF08644 ) FACT complex subunit (SPT16/CDC68)
• ( TIGR02993 ) ectoine utilization protein EutD
• ( PF01402 ) Ribbon-helix-helix protein, copG family
• ( PF07334 ) Interferon-induced 35 kDa protein (IFP

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.6%

TetraMine Data

TTHERM_00283330

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_08971.1	9.997093137033517e-262	metallopeptidase family M24 co ntaining protein (1010 aa)
WormBase	WBGene00018849	5.001363273675253e-167	FACT complex subunit spt-16 status:Confirmed UniProt:Q9N 5R9 protein_id:CCD66831.1
DictyBase	DDB_G0282677	4.998437866964194e-166	spt16 on chromosome: 3 positio n 6105920 to 6109250
Oxytricha	Contig22561.0.g34	6.999646166012048e-157	FACT complex subunit (SPT16/CD C68)
SGD	YGL207W	1.0002534232488231e-144	SPT16 Subunit of the heterodim eric FACT complex (Spt16p-Pob3 p), which associates with chro matin via interaction with Nhp 6Ap and Nhp6Bp, and reorganize s nucleosomes to facilitate ac cess to DNA by RNA and DNA pol ymerases
Stentor Coeruleus	SteCoe_18682	3.257488532207521e-70

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15013445: Fujiu K, Numata O (2004) Identification and molecular cloning of Tetrahymena 138-kDa protein, a transcription elongation factor homologue that interacts with microtubules in vitro. Biochemical and biophysical research communications 315(1):196-203

Sequences

>TTHERM_00283330(coding)
ATGAGCAAAGTTAAAGCTGATATCTTTTATCAACACCATAAGCAGCTATTGAGTGTTTGG
AATAAGCAACCTCAATACGCCAATATCGATGCTTTTATTATTAAAAATGGTAAAGATCAA
GGTGGAAATAAAATCAAAACTTCTGCCATTTCTATGTGGTATTTTGGTTTCGACTTCATT
GACACTATCCTTTTGATCACTAAAAAGACTTTTGCCATTATTGGTGGTAACAAGAAAATA
AACATGTTAAAATCTGTCTAGGAACACGCAGAAGCAAAAGAATACAATTTAGTTTTCATC
GAAAAAGACTAAGCAAACAATTCCAATCAACTTTAATAATTATTTGAAATTCTTGACAAA
GATTTGAACAAATCTAGCTTCAATATTGGAACTCTAGCTAAAGAATAGCAAGTTGGCCCT
TTTATGACTGAGTATGACTCATTTATTAAAGACAAAAATTAATATAAATTTGCTGATTGC
AGTGTATTTGTATAAGATTGTCTCTCTGTAAAAGATCAAAATGAAATATCTTACATTGGA
AAAGCTGCTAAAGTTAGTGTCTATTTAGAGTCTAAATTGATAAAAGAAATTGAAACAATC
ATTGAAGATGAAGGTAAAAAGACTCACAGTCAAATTGCTACTATGATTGAAGGATTGATT
GAAAATGAAAAAGAACTTAAAAAGATCTCAGAAGAAATTGGAGGTGAGAGTGACAATCTT
GATTTGGCTTATGTCCCAATTGTCTAATCTGGCGGCAAATATGATTTAAAACCAAATGCT
TAATCTAATGAAGATATTCTTTCTTATGACACAATTATTGTTTCAGTAGGTACTAAATAT
ATGGAATATCATGCTAATATTGTTCGTACCCTTTTCATTGACCCAACAAACGACTAAAAG
AAGATTTATTAGAGAGTTTATGAGCTCTAAAACTAGATCGCTGTCTAACTTAAGCCTGGT
ATTAAGCTCAAAACTGTTTATGAAAATGCAGTTAATTTCATTAATGAGAAAGTACCTCAA
TTGAAGGATAAGATCCCAGCTAATTTTGGATTTGGTATTGGTTTAGAATTTAGAGAATCT
AACTTGTACATTAATGCTAAAAACGAAAAAGAAGTTGAAGAAGGTATGGTCTTCAATGTT
GTTGTTGGTTTTGACAACTTGCAAAGTGAAAAGGAGAAAGCTTATGCCATACAAATTTCT
GACACTGTTGCAATTAGAAAGTAAAACACACCCAATGCTGTCATGACATTCAAAGTTTCT
AAGAAATATGAAGACATTTCTTACAGCATTTAAGATGAGGGTCAAGATGAAGAATAAGAA
GAGGAAGAAGATGATTTAGAAAAGGAAAACATTATTTAAGATGGACGCAGAACAAGAAAT
GCCTATCACAAAAATACAACTATTGTTTCAGAAAAAGAAAGACAAAAACACTAACTTGAA
TTGAGAGAAGTCAAATTAAAAGAATTACAAGAAAGATATAATAACAATGGATTCTTATCA
AATAAGATCAATTCCAGAGCTCTTGAGTTAGATAAGGTCTAGTGTTATGGTGGACCTCAA
GATATTCCCAAAGAATATAAGAAAAATTAAATTCATATTGATGCTGCTCATAATGCAATC
TTACTTCCTGTAAATGGTGAACTAGTTCCCTTCCACATTTCCTTAATTAAAAACTACTCT
AAAAACGACGAAGGAAAGACTCACACATTACGTCTTAACTTCCACAATCCTGGTAGTGGC
AGCAATTTAGCCAATATTACTTTCCCTAAGATTGATGGCTAAATTGTCTTTATTAAAGAA
CTCACTTTCCGTTCAAAGAACGCTAAAAATATGTTGGAAACAATTAAGAAAATCAAAGAC
TTGCAAGCTAAAGTTAAACAAACTGATCAAGAAGCTAAAAATAAAGACGAATTAGTAGAG
CAAGACAAATTACAATTACGTAACACAAAGAGACCTGCTTTAAGAAATTTAAAAGTACGT
CCTGCTATTTCTAAATAAAAAGTAAATGGTATGTTGGAATTGCACTTAAATGGTTTCAGA
TATATGACAACTAAAAATGAAAAAGTTGATGTCATCTTTAAAAATATAAAACATGCCATC
TTCTAACCTTGCGATAACGAAATGATTGTTGCCATACATTTCAATCTCAAGAATCCTATT
ATGATAGGCAAAAAGAAAGTTTGGGATGTACAATTTTATACAGAAGCTGGTCTTCCCCCA
GAGGATTTAAATAACAGAAGAAGAGGTCATGACTACGATGAAATAGAAGAAGAATAAATG
GAAAAAGCTCGTAGAAAGAAATTAAATAAGGACTTCGAAGCCTTCTACAAAGAAGTTGAA
AACTAGCTTGGAGATAAAATTAAGTTTGAAGTTCCATATGCCAATCTCGGTTTCTACGGT
TCACCAAGTAGATCTACTTGCCTCCTTTAACCTACATAAAATACCCTTATGAACATCATT
GAATTCCCCTTCTTTATCATGTCCTTAGAAGAAGTAGAATTAGCATGCTTCGAAAGAATG
ATCGGAAGACTTAAAAACTTTGATCTTGTCTTTATTTTCAAGGATTATGAAAAACAAGTT
ACAAGAATTGCCTCTATTCCTATTGATAAGGCAGAAATAGTTAAAAATTGGTTAAACAGC
TAAAATATATTGTATTTTGAATCTACAAAGAGTTTCTCTTGGGCTAATATCTTAAAGACC
ATTCGCTAAGATATTGGTGGCTTCATTGAAGATGGAGGTTGGAATATTATTTTGGGTGAA
GATGAAGGAGAAGATGAAGATCCTGATGAGGGTGATGAAGATTTCTCAGTAGAACAAGAC
GAAGAGGAAGAAGAAAGTGAAGAGATTTCTGAAAGTGATGAGGATTTCGATGATGAAGAA
AGTGCGAGTGATTTTGAAGGAGATGAAGATCTCAGTGAAGAAGGCTAAAGCTGGAGCGAT
CTTGAAGAAAACGCTAGAAAGGAAGAAGAGAGAAGAAAGTAACAACAAGTAAAACCAACA
AAGCCTGTTCCTTAAAAAAGAAGATGA

>TTHERM_00283330(protein)
MSKVKADIFYQHHKQLLSVWNKQPQYANIDAFIIKNGKDQGGNKIKTSAISMWYFGFDFI
DTILLITKKTFAIIGGNKKINMLKSVQEHAEAKEYNLVFIEKDQANNSNQLQQLFEILDK
DLNKSSFNIGTLAKEQQVGPFMTEYDSFIKDKNQYKFADCSVFVQDCLSVKDQNEISYIG
KAAKVSVYLESKLIKEIETIIEDEGKKTHSQIATMIEGLIENEKELKKISEEIGGESDNL
DLAYVPIVQSGGKYDLKPNAQSNEDILSYDTIIVSVGTKYMEYHANIVRTLFIDPTNDQK
KIYQRVYELQNQIAVQLKPGIKLKTVYENAVNFINEKVPQLKDKIPANFGFGIGLEFRES
NLYINAKNEKEVEEGMVFNVVVGFDNLQSEKEKAYAIQISDTVAIRKQNTPNAVMTFKVS
KKYEDISYSIQDEGQDEEQEEEEDDLEKENIIQDGRRTRNAYHKNTTIVSEKERQKHQLE
LREVKLKELQERYNNNGFLSNKINSRALELDKVQCYGGPQDIPKEYKKNQIHIDAAHNAI
LLPVNGELVPFHISLIKNYSKNDEGKTHTLRLNFHNPGSGSNLANITFPKIDGQIVFIKE
LTFRSKNAKNMLETIKKIKDLQAKVKQTDQEAKNKDELVEQDKLQLRNTKRPALRNLKVR
PAISKQKVNGMLELHLNGFRYMTTKNEKVDVIFKNIKHAIFQPCDNEMIVAIHFNLKNPI
MIGKKKVWDVQFYTEAGLPPEDLNNRRRGHDYDEIEEEQMEKARRKKLNKDFEAFYKEVE
NQLGDKIKFEVPYANLGFYGSPSRSTCLLQPTQNTLMNIIEFPFFIMSLEEVELACFERM
IGRLKNFDLVFIFKDYEKQVTRIASIPIDKAEIVKNWLNSQNILYFESTKSFSWANILKT
IRQDIGGFIEDGGWNIILGEDEGEDEDPDEGDEDFSVEQDEEEEESEEISESDEDFDDEE
SASDFEGDEDLSEEGQSWSDLEENARKEEERRKQQQVKPTKPVPQKRR

>TTHERM_00283330(gene)
ATGAGCAAAGTTAAAGCTGATATCTTTTATCAACACCATAAGCAGCTATTGAGTGTTTGG
AATAAGGTAATTAGATATACTTTGTTAGCATTTTTTTATATTTTTAATTGCTGGTTTCCA
TTCACTAACTTTTCATTTTATATTCTAGCAACCTCAATACGCCAATATCGATGCTTTTAT
TATTAAAAATGGTAAAGATCAAGGTGGAAATAAAATCAAAACTTCTGCCATTTCTATGTG
GTATTTTGGTTTCGACTTCATTGACACTATCCTTTTGATCACTAAAAAGACTTTTGCCAT
TATTGGTGGTAACAAGAAAAGTAATTTTGCATTTCTAGAATAATTTCATGCATTAAATTT
GTGCTTGATAATGCCAACAATTAGCTAAATTATTTCAATTATAAAAAAGTAAACATGTTA
AAATCTGTCTAGGAACACGCAGAAGCAAAAGAATACAATTTAGTTTTCATCGAAAAAGAC
TAAGCAAACAATTCCAATCAACTTTAATAATTATTTGAAATTCTTGACAAAGATTTGAAC
AAATCTAGCTTCAATGTAAATTCAAATATTATATTTAAATTGAATTTAGACTCATTTTGT
GTCTCAACTGTAATTATGCAGACACAGGCAGGGATGAATCTGAAAGAATTTTAAGCAATT
AAAATAAATTTTATCAAATTTTAACAATTTATTAAAGATTGGAACTCTAGCTAAAGAATA
GCAAGTTGGCCCTTTTATGACTGAGTATGACTCATTTATTAAAGACAAAAATTAATATAA
ATTTGCTGATTGCAGTGTATTTGTATAAGATTGTCTCTCTGTAAAAGATCAAAATGAAAT
AGTAATTTATTTGATATTTAAATTTAGAATACAATTTTTTAAGATAATTATCTGAAAGAG
TTTTAGAAGCTTTTCTTTTGACATAATTTGTTTATTTTGATTTCATTATTTTATTAAACT
TTCTATCCATAACTAAAACAGTCTTACATTGGAAAAGCTGCTAAAGTTAGTGTCTATTTA
GAGTCTAAATTGATAAAAGAAATTGAAACAATCATTGAAGATGAAGGTAAAAAGACTCAC
AGTCAAATTGCTACTATGATTGAAGGATTGATTGAAAATGAAAAAGAACTTAAAAAGATC
TCAGAAGTAAAAAATATTTAACATTATTTAAGTAAAAGCAATATAAAGCAAAGTTCATTC
AAAAAAGCATTGATTATCAAAATTTTCATTTAAGTGCATGATAATTTAAATAAAATAAAA
CGAAGTTTCATTAGGAACTTATAGCAAACAGCAGCAATATAATCATTTGAAATTATGAAT
AGCATTAAGTTATTAAATTTAAAATTTAAATTTATAGGAAATTGGAGGTGAGAGTGACAA
TCTTGATTTGGCTTATGTCCCAATTGTCTAATCTGGCGGCAAATATGATTTAAAGTAAAT
AACTACTTATCCATTTAAAAAATTAAATAAAATACTCATTAAAATATCAATAGACCAAAT
GCTTAATCTAATGAAGATATTCTTTCTTATGACACAATTATTGTTTCAGTAGGTACTAAA
TATATGGAATATCATGCTAATATTGTTCGTACCCTTTTCATTGACCCAACAAACGACTAA
AAGAAGATTTATTAGAGAGTTTATGAGCTCTAAAACTAGATCGCTGTCTAACTTAAGCCT
GGTATTAAGCTCAAAACTGTTTATGAAAATGCAGTTAATTTCATTAATGAGAAAGTACCT
CAATTGAAGGATAAGATCCCAGCTAATTTTGGATTTGGTGTAATAATTTATTTACAATTT
GAGTGCTTTAGCAAGTAATTTAAATTTTTATATTGTATGATAATAGATTGGTTTAGAATT
TAGAGAATCTAACTTGTACATTAATGCTAAAAACGAAAAAGAAGTTGAAGAAGGTATGGT
CTTCAATGTTGTTGTTGGTTTTGACAACTTGCAAAGTGAAAAGGAGAAAGCTTATGCCAT
ACAAATTTCTGACACTGTTGCAATTAGAAAGTAAAACACACCCAATGCTGTCATGACATT
CAAAGTTTCTAAGAAATATGAAGACATTTCTTACAGCATTTAAGATGAGGGTCAAGATGA
AGAATAAGAAGAGGAAGAAGATGATTTAGAAAAGGAAAACATTATTTAAGATGGACGCAG
AACAAGAAATGCCTATCACAAAAATACAACTATTGTTTCAGAAAAAGAAAGACAAAAACA
CTAACTTGAATTGAGAGAAGTCAAATTAAAAGAATTACAAGAAAGATATAATAACAATGG
ATTCTTATCAAATAAGATCAATTCCAGAGCTCTTGAGTTAGATAAGGTCTAGTGTTATGG
TGGACCTCAAGATATTCCCAAAGAATATAAGAAAAATTAAATTCATATTGATGCTGCTCA
TAATGCAATCTTACTTCCTGTAAATGGTGAACTAGTTCCCTTCCACATTTCCTTAATTAA
AAACTACTCTAAAAACGACGAAGGAAAGACTCACACATTACGTCTTAACTTCCACAATGT
AAATAAATATATTAATTTTTACTCATTTTCAAATAATTTATTAATATTATTTACTTTTAA
AAAATAATTAGCCTGGTAGTGGCAGCAATTTAGCCAATATTACTTTCCCTAAGATTGATG
GCTAAATTGTCTTTATTAAAGAACTCACTTTCCGTTCAAAGAACGCTAAAAATATGTTGG
AAACAATTAAGAAAATCAAAGACTTGCAAGCTAAAGTTAAACAAACTGATCAAGAAGCTA
AAAATAAAGACGAATTAGTAGAGCAAGACAAATTACAATTACGTAACACAAAGAGACCTG
CTTTAAGAAATTTAAAAGTACGTCCTGCTATTTCTAAATAAAAAGTAAATGGTATGTTGG
AATTGCACTTAAATGGTTTCAGATATATGACAACTAAAAATGAAAAAGTTGATGTCATCT
TTAAAAATATAAAACATGCCATCTTCTAACCTTGCGATAACGAAATGATTGTTGCCATAC
ATTTCAATCTCAAGAATCCTATTATGATAGGCAAAAAGAAAGTTTGGGATGTACAATTTT
ATACAGAAGCTGGTCTTCCCCCAGAGGATTTAAGTAAGAGAATTTAACATTTTTTTAATG
TTTATTAATAAAATTTAAATTAAATTAATAAAGATAACAGAAGAAGAGGTCATGACTACG
ATGAAATAGAAGAAGAATAAATGGAAAAAGCTCGTAGAAAGAAATTAAATAAGGACTTCG
AAGCCTTCTACAAAGAAGTTGAAAACTAGCTTGGAGATAAAATTAAGTTTGAAGTTCCAT
ATGCCAATCTCGGTTTCTACGGTTCACCAAGTAGATCTACTTGCCTCCTTTAACCTACAT
AAAATACCCTTATGAACATCATTGAATTCCCCTTCTTTATCATGTCCTTAGAAGAAGTAG
AATTAGCATGCTTCGAAAGAATGATCGTAAATAAATTAAAAAAAATTCTATTTAATCAAT
CAAAAAATTTATATAAACTGAATATTTATTTATTTACTTACTTACTTACTTACTTACTAA
CACATTTTTATTTAACTAATTTAGGGAAGACTTAAAAACTTTGATCTTGTCTTTATTTTC
AAGGATTATGAAAAACAAGTTACAAGAATTGCCTCTATTCCTATTGATAAGGCAGAAATA
GTTAAAAATTGGTTAAACAGCTAAAATATATTGTATTTTGAATCTACAAAGAGTTTCTCT
TGGGCTAATATCTTAAAGACCATTCGCTAAGATATTGGTGGCTTCATTGAAGATGGAGGT
TGGAATATTATTTTGGGTGAAGATGAAGGAGAAGATGAAGATCCTGATGAGGGTGATGAA
GATTTCTCAGTAGAACAAGACGAAGAGGAAGAAGAAAGTGAAGAGATTTCTGAAAGTGAT
GAGGATTTCGATGATGAAGAAAGTGCGAGTGATTTTGAAGGAGATGAAGATCTCAGTGAA
GAAGGCTAAAGCTGGAGCGATCTTGAAGAAAACGCTAGAAGTAATTAATTAATTAATTTT
TATCAATAATTGATAAATTTAAGAATAATCTAATTTATTTTTAATAATACAGAGGAAGAA
GAGAGAAGAAAGTAACAACAAGTAAAACCAACAAAGCCTGTTCCTTAAAAAAGAAGATGA