Gene Model Identifier
TTHERM_00283330
Standard Name
CET1
Aliases
PreTt04872 | 25.m00336 | p138 | 3694.m00119 | Spt16
Description
CET1 metallopeptidase family M24 containing protein; Protein associated with macronulear microtubules; sequence similarity to human transcription elongation factor FACT 140 kDa subunit- yeast Spt16/Cdc68- and Xenopus DUF140
Genome Browser (Macronucleus)
Genome Browser (Micronucleus)
Cellular Component Molecular Function
( PF02016 ) LD-carboxypeptidase
( PF00557 ) peptidase, M24 family
( PF08512 ) Histone chaperone Rttp106-like
( PF08644 ) FACT complex subunit (SPT16/CDC68)
( TIGR02993 ) ectoine utilization protein EutD
( PF01402 ) Ribbon-helix-helix protein, copG family
( PF07334 ) Interferon-induced 35 kDa protein (IFP
Tetrahymena Functional Genomics Database:
Signal Peptide Present?: No
TTHERM_00283330
Fullscreen View
No Data fetched for StockID
(v.2006 protein sequences)
Source Identifier Score Description
Tetrahymena borealis EI9_08971.1 9.997093137033517e-262 metallopeptidase family M24 co
WormBase WBGene00018849 5.001363273675253e-167 FACT complex subunit spt-16
DictyBase DDB_G0282677 4.998437866964194e-166 spt16 on chromosome: 3 positio
Oxytricha Contig22561.0.g34 6.999646166012048e-157 FACT complex subunit (SPT16/CD
SGD YGL207W 1.0002534232488231e-144 SPT16 Subunit of the heterodim
Stentor Coeruleus SteCoe_18682 3.257488532207521e-70
Paragraph No Gene Name Paragraph Text 128 CET1 The FACT-complex is a critical transcription regulator and an H2A/H2B chaperone. Affinity purification followed by mass spectrometry (AP-MS) of endogenously tagged T. thermophila histones H2A/H2B identified Cet1 and Pob3 subunits of the FACT complex as high-confidence interacting partners. Indirect immunofluorescence studies using endogenously tagged Cet1 indicated that it localized to both the MAC and MIC during vegetative growth. AP-MS analysis using Tetrahymena Cet1 as a bait protein revealed Pob3 and subunits of RNA polymerase as high-confidence co-purifying proteins (Ashraf et al. 2019).
Ref:34086947 : Nabeel-Shah S, Garg J, Saettone A, Ashraf K, Lee H, Wahab S, Ahmed N, Fine J, Derynck J, Pu S, Ponce M, Marcon E, Zhang Z, Greenblatt JF, Pearlman RE, Lambert JP, Fillingham J (2021) Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. Nucleic acids research ( ): Ref:30796450 : Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J (2019) Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular biology and evolution ( ): Ref:15013445 : Fujiu K, Numata O (2004) Identification and molecular cloning of Tetrahymena 138-kDa protein, a transcription elongation factor homologue that interacts with microtubules in vitro. Biochemical and biophysical research communications 315(1):196-203
>TTHERM_00283330(coding)ATG AGC AAA GTT AAA GCT GAT ATC TTT TAT CAA CAC CAT AAG CAG CTA TTG AGT GTT TGG AAT AAG CAA CCT CAA TAC GCC AAT ATC GAT GCT TTT ATT ATT AAA AAT GGT AAA GAT CAA GGT GGA AAT AAA ATC AAA ACT TCT GCC ATT TCT ATG TGG TAT TTT GGT TTC GAC TTC ATT GAC ACT ATC CTT TTG ATC ACT AAA AAG ACT TTT GCC ATT ATT GGT GGT AAC AAG AAA ATA AAC ATG TTA AAA TCT GTC TAG GAA CAC GCA GAA GCA AAA GAA TAC AAT TTA GTT TTC ATC GAA AAA GAC TAA GCA AAC AAT TCC AAT CAA CTT TAA TAA TTA TTT GAA ATT CTT GAC AAA GAT TTG AAC AAA TCT AGC TTC AAT ATT GGA ACT CTA GCT AAA GAA TAG CAA GTT GGC CCT TTT ATG ACT GAG TAT GAC TCA TTT ATT AAA GAC AAA AAT TAA TAT AAA TTT GCT GAT TGC AGT GTA TTT GTA TAA GAT TGT CTC TCT GTA AAA GAT CAA AAT GAA ATA TCT TAC ATT GGA AAA GCT GCT AAA GTT AGT GTC TAT TTA GAG TCT AAA TTG ATA AAA GAA ATT GAA ACA ATC ATT GAA GAT GAA GGT AAA AAG ACT CAC AGT CAA ATT GCT ACT ATG ATT GAA GGA TTG ATT GAA AAT GAA AAA GAA CTT AAA AAG ATC TCA GAA GAA ATT GGA GGT GAG AGT GAC AAT CTT GAT TTG GCT TAT GTC CCA ATT GTC TAA TCT GGC GGC AAA TAT GAT TTA AAA CCA AAT GCT TAA TCT AAT GAA GAT ATT CTT TCT TAT GAC ACA ATT ATT GTT TCA GTA GGT ACT AAA TAT ATG GAA TAT CAT GCT AAT ATT GTT CGT ACC CTT TTC ATT GAC CCA ACA AAC GAC TAA AAG AAG ATT TAT TAG AGA GTT TAT GAG CTC TAA AAC TAG ATC GCT GTC TAA CTT AAG CCT GGT ATT AAG CTC AAA ACT GTT TAT GAA AAT GCA GTT AAT TTC ATT AAT GAG AAA GTA CCT CAA TTG AAG GAT AAG ATC CCA GCT AAT TTT GGA TTT GGT ATT GGT TTA GAA TTT AGA GAA TCT AAC TTG TAC ATT AAT GCT AAA AAC GAA AAA GAA GTT GAA GAA GGT ATG GTC TTC AAT GTT GTT GTT GGT TTT GAC AAC TTG CAA AGT GAA AAG GAG AAA GCT TAT GCC ATA CAA ATT TCT GAC ACT GTT GCA ATT AGA AAG TAA AAC ACA CCC AAT GCT GTC ATG ACA TTC AAA GTT TCT AAG AAA TAT GAA GAC ATT TCT TAC AGC ATT TAA GAT GAG GGT CAA GAT GAA GAA TAA GAA GAG GAA GAA GAT GAT TTA GAA AAG GAA AAC ATT ATT TAA GAT GGA CGC AGA ACA AGA AAT GCC TAT CAC AAA AAT ACA ACT ATT GTT TCA GAA AAA GAA AGA CAA AAA CAC TAA CTT GAA TTG AGA GAA GTC AAA TTA AAA GAA TTA CAA GAA AGA TAT AAT AAC AAT GGA TTC TTA TCA AAT AAG ATC AAT TCC AGA GCT CTT GAG TTA GAT AAG GTC TAG TGT TAT GGT GGA CCT CAA GAT ATT CCC AAA GAA TAT AAG AAA AAT TAA ATT CAT ATT GAT GCT GCT CAT AAT GCA ATC TTA CTT CCT GTA AAT GGT GAA CTA GTT CCC TTC CAC ATT TCC TTA ATT AAA AAC TAC TCT AAA AAC GAC GAA GGA AAG ACT CAC ACA TTA CGT CTT AAC TTC CAC AAT CCT GGT AGT GGC AGC AAT TTA GCC AAT ATT ACT TTC CCT AAG ATT GAT GGC TAA ATT GTC TTT ATT AAA GAA CTC ACT TTC CGT TCA AAG AAC GCT AAA AAT ATG TTG GAA ACA ATT AAG AAA ATC AAA GAC TTG CAA GCT AAA GTT AAA CAA ACT GAT CAA GAA GCT AAA AAT AAA GAC GAA TTA GTA GAG CAA GAC AAA TTA CAA TTA CGT AAC ACA AAG AGA CCT GCT TTA AGA AAT TTA AAA GTA CGT CCT GCT ATT TCT AAA TAA AAA GTA AAT GGT ATG TTG GAA TTG CAC TTA AAT GGT TTC AGA TAT ATG ACA ACT AAA AAT GAA AAA GTT GAT GTC ATC TTT AAA AAT ATA AAA CAT GCC ATC TTC TAA CCT TGC GAT AAC GAA ATG ATT GTT GCC ATA CAT TTC AAT CTC AAG AAT CCT ATT ATG ATA GGC AAA AAG AAA GTT TGG GAT GTA CAA TTT TAT ACA GAA GCT GGT CTT CCC CCA GAG GAT TTA AAT AAC AGA AGA AGA GGT CAT GAC TAC GAT GAA ATA GAA GAA GAA TAA ATG GAA AAA GCT CGT AGA AAG AAA TTA AAT AAG GAC TTC GAA GCC TTC TAC AAA GAA GTT GAA AAC TAG CTT GGA GAT AAA ATT AAG TTT GAA GTT CCA TAT GCC AAT CTC GGT TTC TAC GGT TCA CCA AGT AGA TCT ACT TGC CTC CTT TAA CCT ACA TAA AAT ACC CTT ATG AAC ATC ATT GAA TTC CCC TTC TTT ATC ATG TCC TTA GAA GAA GTA GAA TTA GCA TGC TTC GAA AGA ATG ATC GGA AGA CTT AAA AAC TTT GAT CTT GTC TTT ATT TTC AAG GAT TAT GAA AAA CAA GTT ACA AGA ATT GCC TCT ATT CCT ATT GAT AAG GCA GAA ATA GTT AAA AAT TGG TTA AAC AGC TAA AAT ATA TTG TAT TTT GAA TCT ACA AAG AGT TTC TCT TGG GCT AAT ATC TTA AAG ACC ATT CGC TAA GAT ATT GGT GGC TTC ATT GAA GAT GGA GGT TGG AAT ATT ATT TTG GGT GAA GAT GAA GGA GAA GAT GAA GAT CCT GAT GAG GGT GAT GAA GAT TTC TCA GTA GAA CAA GAC GAA GAG GAA GAA GAA AGT GAA GAG ATT TCT GAA AGT GAT GAG GAT TTC GAT GAT GAA GAA AGT GCG AGT GAT TTT GAA GGA GAT GAA GAT CTC AGT GAA GAA GGC TAA AGC TGG AGC GAT CTT GAA GAA AAC GCT AGA AAG GAA GAA GAG AGA AGA AAG TAA CAA CAA GTA AAA CCA ACA AAG CCT GTT CCT TAA AAA AGA AGA TGA >TTHERM_00283330(protein)M S K V K A D I F Y Q H H K Q L L S V W N K Q P Q Y A N I D A F I I K N G K D Q G G N K I K T S A I S M W Y F G F D F I D T I L L I T K K T F A I I G G N K K I N M L K S V Q E H A E A K E Y N L V F I E K D Q A N N S N Q L Q Q L F E I L D K D L N K S S F N I G T L A K E Q Q V G P F M T E Y D S F I K D K N Q Y K F A D C S V F V Q D C L S V K D Q N E I S Y I G K A A K V S V Y L E S K L I K E I E T I I E D E G K K T H S Q I A T M I E G L I E N E K E L K K I S E E I G G E S D N L D L A Y V P I V Q S G G K Y D L K P N A Q S N E D I L S Y D T I I V S V G T K Y M E Y H A N I V R T L F I D P T N D Q K K I Y Q R V Y E L Q N Q I A V Q L K P G I K L K T V Y E N A V N F I N E K V P Q L K D K I P A N F G F G I G L E F R E S N L Y I N A K N E K E V E E G M V F N V V V G F D N L Q S E K E K A Y A I Q I S D T V A I R K Q N T P N A V M T F K V S K K Y E D I S Y S I Q D E G Q D E E Q E E E E D D L E K E N I I Q D G R R T R N A Y H K N T T I V S E K E R Q K H Q L E L R E V K L K E L Q E R Y N N N G F L S N K I N S R A L E L D K V Q C Y G G P Q D I P K E Y K K N Q I H I D A A H N A I L L P V N G E L V P F H I S L I K N Y S K N D E G K T H T L R L N F H N P G S G S N L A N I T F P K I D G Q I V F I K E L T F R S K N A K N M L E T I K K I K D L Q A K V K Q T D Q E A K N K D E L V E Q D K L Q L R N T K R P A L R N L K V R P A I S K Q K V N G M L E L H L N G F R Y M T T K N E K V D V I F K N I K H A I F Q P C D N E M I V A I H F N L K N P I M I G K K K V W D V Q F Y T E A G L P P E D L N N R R R G H D Y D E I E E E Q M E K A R R K K L N K D F E A F Y K E V E N Q L G D K I K F E V P Y A N L G F Y G S P S R S T C L L Q P T Q N T L M N I I E F P F F I M S L E E V E L A C F E R M I G R L K N F D L V F I F K D Y E K Q V T R I A S I P I D K A E I V K N W L N S Q N I L Y F E S T K S F S W A N I L K T I R Q D I G G F I E D G G W N I I L G E D E G E D E D P D E G D E D F S V E Q D E E E E E S E E I S E S D E D F D D E E S A S D F E G D E D L S E E G Q S W S D L E E N A R K E E E R R K Q Q Q V K P T K P V P Q K R R >TTHERM_00283330(gene)ATG AGC AAA GTT AAA GCT GAT ATC TTT TAT CAA CAC CAT AAG CAG CTA TTG AGT GTT TGG AAT AAG GTA ATT AGA TAT ACT TTG TTA GCA TTT TTT TAT ATT TTT AAT TGC TGG TTT CCA TTC ACT AAC TTT TCA TTT TAT ATT CTA GCA ACC TCA ATA CGC CAA TAT CGA TGC TTT TAT TAT TAA AAA TGG TAA AGA TCA AGG TGG AAA TAA AAT CAA AAC TTC TGC CAT TTC TAT GTG GTA TTT TGG TTT CGA CTT CAT TGA CAC TAT CCT TTT GAT CAC TAA AAA GAC TTT TGC CAT TAT TGG TGG TAA CAA GAA AAG TAA TTT TGC ATT TCT AGA ATA ATT TCA TGC ATT AAA TTT GTG CTT GAT AAT GCC AAC AAT TAG CTA AAT TAT TTC AAT TAT AAA AAA GTA AAC ATG TTA AAA TCT GTC TAG GAA CAC GCA GAA GCA AAA GAA TAC AAT TTA GTT TTC ATC GAA AAA GAC TAA GCA AAC AAT TCC AAT CAA CTT TAA TAA TTA TTT GAA ATT CTT GAC AAA GAT TTG AAC AAA TCT AGC TTC AAT GTA AAT TCA AAT ATT ATA TTT AAA TTG AAT TTA GAC TCA TTT TGT GTC TCA ACT GTA ATT ATG CAG ACA CAG GCA GGG ATG AAT CTG AAA GAA TTT TAA GCA ATT AAA ATA AAT TTT ATC AAA TTT TAA CAA TTT ATT AAA GAT TGG AAC TCT AGC TAA AGA ATA GCA AGT TGG CCC TTT TAT GAC TGA GTA TGA CTC ATT TAT TAA AGA CAA AAA TTA ATA TAA ATT TGC TGA TTG CAG TGT ATT TGT ATA AGA TTG TCT CTC TGT AAA AGA TCA AAA TGA AAT AGT AAT TTA TTT GAT ATT TAA ATT TAG AAT ACA ATT TTT TAA GAT AAT TAT CTG AAA GAG TTT TAG AAG CTT TTC TTT TGA CAT AAT TTG TTT ATT TTG ATT TCA TTA TTT TAT TAA ACT TTC TAT CCA TAA CTA AAA CAG TCT TAC ATT GGA AAA GCT GCT AAA GTT AGT GTC TAT TTA GAG TCT AAA TTG ATA AAA GAA ATT GAA ACA ATC ATT GAA GAT GAA GGT AAA AAG ACT CAC AGT CAA ATT GCT ACT ATG ATT GAA GGA TTG ATT GAA AAT GAA AAA GAA CTT AAA AAG ATC TCA GAA GTA AAA AAT ATT TAA CAT TAT TTA AGT AAA AGC AAT ATA AAG CAA AGT TCA TTC AAA AAA GCA TTG ATT ATC AAA ATT TTC ATT TAA GTG CAT GAT AAT TTA AAT AAA ATA AAA CGA AGT TTC ATT AGG AAC TTA TAG CAA ACA GCA GCA ATA TAA TCA TTT GAA ATT ATG AAT AGC ATT AAG TTA TTA AAT TTA AAA TTT AAA TTT ATA GGA AAT TGG AGG TGA GAG TGA CAA TCT TGA TTT GGC TTA TGT CCC AAT TGT CTA ATC TGG CGG CAA ATA TGA TTT AAA GTA AAT AAC TAC TTA TCC ATT TAA AAA ATT AAA TAA AAT ACT CAT TAA AAT ATC AAT AGA CCA AAT GCT TAA TCT AAT GAA GAT ATT CTT TCT TAT GAC ACA ATT ATT GTT TCA GTA GGT ACT AAA TAT ATG GAA TAT CAT GCT AAT ATT GTT CGT ACC CTT TTC ATT GAC CCA ACA AAC GAC TAA AAG AAG ATT TAT TAG AGA GTT TAT GAG CTC TAA AAC TAG ATC GCT GTC TAA CTT AAG CCT GGT ATT AAG CTC AAA ACT GTT TAT GAA AAT GCA GTT AAT TTC ATT AAT GAG AAA GTA CCT CAA TTG AAG GAT AAG ATC CCA GCT AAT TTT GGA TTT GGT GTA ATA ATT TAT TTA CAA TTT GAG TGC TTT AGC AAG TAA TTT AAA TTT TTA TAT TGT ATG ATA ATA GAT TGG TTT AGA ATT TAG AGA ATC TAA CTT GTA CAT TAA TGC TAA AAA CGA AAA AGA AGT TGA AGA AGG TAT GGT CTT CAA TGT TGT TGT TGG TTT TGA CAA CTT GCA AAG TGA AAA GGA GAA AGC TTA TGC CAT ACA AAT TTC TGA CAC TGT TGC AAT TAG AAA GTA AAA CAC ACC CAA TGC TGT CAT GAC ATT CAA AGT TTC TAA GAA ATA TGA AGA CAT TTC TTA CAG CAT TTA AGA TGA GGG TCA AGA TGA AGA ATA AGA AGA GGA AGA AGA TGA TTT AGA AAA GGA AAA CAT TAT TTA AGA TGG ACG CAG AAC AAG AAA TGC CTA TCA CAA AAA TAC AAC TAT TGT TTC AGA AAA AGA AAG ACA AAA ACA CTA ACT TGA ATT GAG AGA AGT CAA ATT AAA AGA ATT ACA AGA AAG ATA TAA TAA CAA TGG ATT CTT ATC AAA TAA GAT CAA TTC CAG AGC TCT TGA GTT AGA TAA GGT CTA GTG TTA TGG TGG ACC TCA AGA TAT TCC CAA AGA ATA TAA GAA AAA TTA AAT TCA TAT TGA TGC TGC TCA TAA TGC AAT CTT ACT TCC TGT AAA TGG TGA ACT AGT TCC CTT CCA CAT TTC CTT AAT TAA AAA CTA CTC TAA AAA CGA CGA AGG AAA GAC TCA CAC ATT ACG TCT TAA CTT CCA CAA TGT AAA TAA ATA TAT TAA TTT TTA CTC ATT TTC AAA TAA TTT ATT AAT ATT ATT TAC TTT TAA AAA ATA ATT AGC CTG GTA GTG GCA GCA ATT TAG CCA ATA TTA CTT TCC CTA AGA TTG ATG GCT AAA TTG TCT TTA TTA AAG AAC TCA CTT TCC GTT CAA AGA ACG CTA AAA ATA TGT TGG AAA CAA TTA AGA AAA TCA AAG ACT TGC AAG CTA AAG TTA AAC AAA CTG ATC AAG AAG CTA AAA ATA AAG ACG AAT TAG TAG AGC AAG ACA AAT TAC AAT TAC GTA ACA CAA AGA GAC CTG CTT TAA GAA ATT TAA AAG TAC GTC CTG CTA TTT CTA AAT AAA AAG TAA ATG GTA TGT TGG AAT TGC ACT TAA ATG GTT TCA GAT ATA TGA CAA CTA AAA ATG AAA AAG TTG ATG TCA TCT TTA AAA ATA TAA AAC ATG CCA TCT TCT AAC CTT GCG ATA ACG AAA TGA TTG TTG CCA TAC ATT TCA ATC TCA AGA ATC CTA TTA TGA TAG GCA AAA AGA AAG TTT GGG ATG TAC AAT TTT ATA CAG AAG CTG GTC TTC CCC CAG AGG ATT TAA GTA AGA GAA TTT AAC ATT TTT TTA ATG TTT ATT AAT AAA ATT TAA ATT AAA TTA ATA AAG ATA ACA GAA GAA GAG GTC ATG ACT ACG ATG AAA TAG AAG AAG AAT AAA TGG AAA AAG CTC GTA GAA AGA AAT TAA ATA AGG ACT TCG AAG CCT TCT ACA AAG AAG TTG AAA ACT AGC TTG GAG ATA AAA TTA AGT TTG AAG TTC CAT ATG CCA ATC TCG GTT TCT ACG GTT CAC CAA GTA GAT CTA CTT GCC TCC TTT AAC CTA CAT AAA ATA CCC TTA TGA ACA TCA TTG AAT TCC CCT TCT TTA TCA TGT CCT TAG AAG AAG TAG AAT TAG CAT GCT TCG AAA GAA TGA TCG TAA ATA AAT TAA AAA AAA TTC TAT TTA ATC AAT CAA AAA ATT TAT ATA AAC TGA ATA TTT ATT TAT TTA CTT ACT TAC TTA CTT ACT TAC TAA CAC ATT TTT ATT TAA CTA ATT TAG GGA AGA CTT AAA AAC TTT GAT CTT GTC TTT ATT TTC AAG GAT TAT GAA AAA CAA GTT ACA AGA ATT GCC TCT ATT CCT ATT GAT AAG GCA GAA ATA GTT AAA AAT TGG TTA AAC AGC TAA AAT ATA TTG TAT TTT GAA TCT ACA AAG AGT TTC TCT TGG GCT AAT ATC TTA AAG ACC ATT CGC TAA GAT ATT GGT GGC TTC ATT GAA GAT GGA GGT TGG AAT ATT ATT TTG GGT GAA GAT GAA GGA GAA GAT GAA GAT CCT GAT GAG GGT GAT GAA GAT TTC TCA GTA GAA CAA GAC GAA GAG GAA GAA GAA AGT GAA GAG ATT TCT GAA AGT GAT GAG GAT TTC GAT GAT GAA GAA AGT GCG AGT GAT TTT GAA GGA GAT GAA GAT CTC AGT GAA GAA GGC TAA AGC TGG AGC GAT CTT GAA GAA AAC GCT AGA AGT AAT TAA TTA ATT AAT TTT TAT CAA TAA TTG ATA AAT TTA AGA ATA ATC TAA TTT ATT TTT AAT AAT ACA GAG GAA GAA GAG AGA AGA AAG TAA CAA CAA GTA AAA CCA ACA AAG CCT GTT CCT TAA AAA AGA AGA TGA
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