Identifiers and Description

Gene Model Identifier

TTHERM_00444870

Standard Name

CEN4 (CENtrin 4)

Aliases

PreTt03855 | 51.m00221 | 3704.m00077

Description

EF hand family protein, centrin family member; EF-hand calcium-binding protein; also called caltractin; GFP-fusion protein localized to specialized structures of oral apparatus, along deep rootlet, and at contractile vacuole pore

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF08730 ) Rad33
• ( PF00036 ) EF hand
• ( TIGR01784 ) conserved hypothetical protein
• ( PF07498 ) Rho termination factor, N-terminal domain

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.1%

TetraMine Data

TTHERM_00444870

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_10867.1	4.9996115996408327e-110	EF hand family protein (175 aa )
Oxytricha	Contig22557.0.g47	9.004385969422137e-73	EF-hand domain pair
Stentor Coeruleus	SteCoe_37504	3.6251409191435593e-34
SGD	YOR257W	3.000555717977434e-27	CDC31 Calcium-binding componen t of the spindle pole body (SP B) half-bridge, required for S PB duplication in mitosis and meiosis II; homolog of mammali an centrin; binds multiubiquit inated proteins and is involve d in proteasomal protein degra dation
DictyBase	DDB_G0279407	3.0002687256732656e-20	calA on chromosome: 3 position 2244074 to 2245039
WormBase	WBGene00000552	1.9999391735788327e-19	locus:cmd-1 Calmodulin sta tus:Confirmed UniProt:O16305 protein_id:CCD69969.1

General Information

No Data fetched for General Information

Associated Literature

1. Ref:15944224: Stemm-Wolf AJ, Morgan G, Giddings TH, White EA, Marchione R, McDonald HB, Winey M (2005) Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family. Molecular biology of the cell 16(8):3606-19
2. Ref:9163921: Guerrini AM, Ascenzioni F, Gallo T, Donini P (1997) Yeast linear plasmids with T2AG3 telomeres: TEL+CEN antagonism and genetic and molecular stability. FEMS microbiology letters 150(1):165-71
3. Ref:2190243: Ascenzioni F, Guerrini AM, Donini P (1990) Functional telomere formation in yeast using synthetic C4A2 sequences. Plasmid 23(1):16-26

Sequences

>TTHERM_00444870(coding)
ATGAATTCAAAGAAAACTGTTGCTCCTTAAGGTAAAAATTTTGGCGTTGCTAACAAGAAG
TAACCTTAATAAAGACCTGGTTTGACTGAAGATGAAATTGAAGAAATAAGAGAAGCCTTC
AACTTATTCGATACTGAAGGTTCTGGTAAGATTGATCCCAGAGAATTAAAAGCAGCCATG
CAATCGTTGGGTTTTGAAAATAAGAATCCTACTATCTATGGTATGATCGCTGATTTAGAA
AGTTAAGGAACAGAAATTGATTTTGAAGATTTCTTAGATGCTATTACCTCAAAGCTTGGA
GACAAAGAAACTAGAGACGGAATTAACAAAATCTTTGAGTTATTTGATGATGATTAAACT
AAGAGTATTACTTTGAAGAATTTAATGCGTGTTGCTAAGGAATTAGGTGAAACAATGACC
TAAGAAGAATTAGCTGAGATGTTAGAACGTGCCGCTAGCAATAGCAGAGAAATTACCCCT
GAAGATTTCTACAACATCATGGTCAAGAAAACTTTCTGA

>TTHERM_00444870(protein)
MNSKKTVAPQGKNFGVANKKQPQQRPGLTEDEIEEIREAFNLFDTEGSGKIDPRELKAAM
QSLGFENKNPTIYGMIADLESQGTEIDFEDFLDAITSKLGDKETRDGINKIFELFDDDQT
KSITLKNLMRVAKELGETMTQEELAEMLERAASNSREITPEDFYNIMVKKTF

>TTHERM_00444870(gene)
ATGAATTCAAAGAAAACTGTTGCTCCTTAAGGTAAAAATTTTGGCGTTGCTAACAAGAAG
TAACCTTAATAAAGACCTGGTTTGACTGAAGATGAAATTGAAGAAATAAGAGAAGCCTTC
AACTTATTCGATACTGAAGGTTCTGGTAAGATTGATCCCAGAGAATTAAAAGCAGCCATG
CAATCGTTGGGTTTTGAAAATAAGAATCCTACTATCTATGGTATGATCGCTGATTTAGAA
AGTTAAGGAACAGAAATTGATTTTGAAGATTTCTTAGATGCTATTACCTCAAAGCTTGGA
GACAAAGAAACTAGAGACGGAATTAACAAAATCTTTGAGTTATTTGATGATGATTAAACT
AAGAGTATTACTTTGAAGAATTTAATGCGTGTTGCTAAGGAATTAGGTGAAACAATGACC
TAAGAAGAATTAGCTGAGATGTTAGAACGTGCCGCTAGCAATAGCAGAGAAATTACCCCT
GAAGATTTCTACAACATCATGGTCAAGAAAACTTTCTGA