Identifiers and Description

Gene Model Identifier

TTHERM_00523060

Standard Name

CEN2 (CENtrin 2)

Aliases

PreTt12421 | 65.m00239 | 3717.m00118

Description

Centrin family member, EF-hand calcium-binding protein; basal bodies require a centrin from both CEN1 and CEN2 to function correctly; expression of endogenous gene not detected during vegetative growth or conjugation series

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• oral apparatus (IDA) | GO:0031912 | Ref:23087207
• ciliary basal body (IDA) | GO:0036064 | Ref:23087207

Biological Process

• ciliary basal body organization (IMP) | GO:0032053 | Ref:23087207

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00523060

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_12795.1	9.997093137033517e-262	EF hand family protein (368 aa )
Oxytricha	Contig473.1.g50	0.0005997485943342685	GCC2 and GCC3

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23087207: Vonderfecht T, Cookson MW, Giddings TH, Clarissa C, Winey M (2012) The two human centrin homologues have similar but distinct functions at Tetrahymena basal bodies. Molecular biology of the cell 23(24):4766-77
2. Ref:15944224: Stemm-Wolf AJ, Morgan G, Giddings TH, White EA, Marchione R, McDonald HB, Winey M (2005) Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family. Molecular biology of the cell 16(8):3606-19

Sequences

>TTHERM_00523060(coding)
ATGGAATCATATTCTTATAATTCAGGTCTAAAAGAAGTTACCTTTGATGAAAAAGAATCT
ATGTCAGAAAGAGGAACCTCTTTAGGAGGAGATGATTATCATCTAACAGAATCAGTGATA
GATAAATAAATGAAGGATTTCTAACAAGATAGAAGGAGTTTAGAAGATCCTGATTAGATT
AACTTTAATGACCCAATATTTAAAAGGATCTTGGGAGATGACGAGTTAAAGACGTTAGAC
TAAACTCTACCTTAAAAGTGTATCAAATGTGAATGCAAATTTAATTCTATAACTAATAGG
AAGTTTCAGTGTTACTTTTGTGGGTATCCAGTTTGCAAAGACCATTCTAAAAAAAAGAGA
GAAGATCCCTCAAAGCTAAACACAAGCAATAACAAGTCAATAAATAATCAAAATAATAGT
ACTATATTGAATACATCTGGAGGAGAAAGTGAATATGAAAAAAAAAATTTTAAGAAAATA
TGTGACATTTGTGAAGATAAATATCTGAAGTGGCAAATAAACTTTTCATTCTAGTAAAAG
AAGGATCAATATGATGAAGTTACATAAAGGTTAGAAAAATAACAAAAAGATATTTTAGAA
AAAATAAAAAAATAATAAGACGAAATAAGTAGAATATAGTCATAGGAAGAACAAAAAAAG
AAACAGTTTGAAGATTAAAAGAATGAAATATTAAAGAAGATTGAAAAAGCAGAAATGGAG
GATACAGATCTTAAAAAGGAAAACAAAGACTATTTATTAAAAATAGATAAAATAGATACT
GAAATTAATAGCATGATGAAATAAATAAAAGAAATCGATGAGGAATATAAGCAAAAGGTA
ACAGAAGAAAAGAATTTAACCTAAAAAATAAAAGAAATAGACTAAGAAATAGAAAATGCT
CACTAAATTATTGAAGAAATAGAATAAAAAATCACAGACAATAATCTGATGATGTAGAGA
TAAAAGTAAATTTATGATGTCAGAGATTCTCGTTTAGATAGCAATTTAGATAATATTAGA
GAAAACTCTGCAATTAGAGCTAGAAAAGATTAGAATATAGATAAAGAAAAAAATTGTAAT
GTATGCTAAATCTTTTGA

>TTHERM_00523060(protein)
MESYSYNSGLKEVTFDEKESMSERGTSLGGDDYHLTESVIDKQMKDFQQDRRSLEDPDQI
NFNDPIFKRILGDDELKTLDQTLPQKCIKCECKFNSITNRKFQCYFCGYPVCKDHSKKKR
EDPSKLNTSNNKSINNQNNSTILNTSGGESEYEKKNFKKICDICEDKYLKWQINFSFQQK
KDQYDEVTQRLEKQQKDILEKIKKQQDEISRIQSQEEQKKKQFEDQKNEILKKIEKAEME
DTDLKKENKDYLLKIDKIDTEINSMMKQIKEIDEEYKQKVTEEKNLTQKIKEIDQEIENA
HQIIEEIEQKITDNNLMMQRQKQIYDVRDSRLDSNLDNIRENSAIRARKDQNIDKEKNCN
VCQIF

>TTHERM_00523060(gene)
ATGGAATCATATTCTTATAATTCAGGTCTAAAAGAAGTTACCTTTGATGAAAAAGGTTTA
TTTTTTATTCTTCTACTATTTAAACGCTTAACTGTAAATAATTAATGTTCTATTTTCTAA
CATGAATAGAATCTATGTCAGAAAGAGGAACCTCTTTAGGAGGAGATGATTATCATCTAA
CAGAATCAGTGATAGATAAATAAATGAAGGATTTCTAACAAGATAGAAGGAGTTTAGAAG
ATCCTGATTAGATTAACTTTAATGACCGTACAAAAATTTTAATTCACTAGATTATGCAAT
TTTTTTATCAGCAATATTTAAAAGGATCTTGGGAGATGACGAGTTAAAGACGTTAGACTA
AACTCTACCTTAAAAGTGTATCAAATGTGAATGCAAATTTAATTCTATAACTAATAGGAA
GTTTCAGTGGTAATTTAATTATAGATTAGCTCATCATATGTTTATATTTAGAATTTAAAA
TTTAAAATATGAAGAATTTAAGCAGTTTTTAATCCTATTTTTAGAATAAAATGTTGTTGA
GGTTCGTTTTTTAGAATTTTAATTTCTTAAAATAAAAGTTACTTTTGTGGGTATCCAGTT
TGCAAAGACCATTCTAAAAAAAAGAGAGAAGATCCCTCAAAGCTAAACACAAGCAATAAC
AAGTCAATAAATAATCAAAATAATAGTACTATATTGAATACATCTGGAGGAGAAAGTGAA
TATGAAAAAAAAAATTTTAAGAAAATATGTGACATTTGTGAAGATAAATATCTGAAGTGG
CAAATAAACTTTTCATTCTAGTAAAAGAAGGATCAATATGATGAAGTTACATAAAGGTTA
GAAAAATAACAAAAAGATATTTTAGAAAAAATAAAAAAATAATAAGACGAAATAAGTAGA
ATATAGTCATAGGTAAAACCAATAAATATTAAATGAAGTTTATCTTTAATTGCCTAAACA
ATAATTATTTATTTAAATAGGAAGAACAAAAAAAGAAACAGTTTGAAGATTAAAAGAATG
AAATATTAAAGAAGATTGAAAAAGCAGAAATGGAGGATACAGATCTTAAAAAGGAAAACA
AAGACTATTTATTAAAAATAGATAAAATAGATACTGAAATTAATAGCATGATGAAATAAA
TAAAAGAAATCGATGAGGAATATAAGCAAAAGTATTTAATTAATCAATTTACTTTATTTA
TTTATTTAGTATTTATAGTTAATCAACATATATTTTAAAATGCTATTAGGGTAACAGAAG
AAAAGAATTTAACCTAAAAAATAAAAGAAATAGACTAAGAAATAGAAAATGCTCACTAAA
TTATTGAAGAAATAGAATAAAAAATCACAGACAATAATCTGATGATGTAGAGATAAAAGT
AAATTTATGATGTCAGAGATTCTCGTTTAGATAGCAATTTAGATAATATTAGAGAAAACT
CTGCAATTAGAGCTAGAAAAGATTAGAATATAGATAAAGAAAAAAATTGTAATGTATGCT
AAATCTTTTGA