Identifiers and Description

Gene Model Identifier

TTHERM_00760200

Standard Name

CEG1 (Capping Enzyme Guanylyltransferase 1)

Aliases

PreTt18505 | 125.m00069 | 3672.m00002

Description

Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, (in Yeast the other subunit is CET1, an RNA 5'-triphosphatase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• mRNA guanylyltransferase activity (IEA) | GO:0004484

Biological Process

• 7-methylguanosine mRNA capping (IEA) | GO:0006370
• mRNA processing (IEA) | GO:0006397

Domains

• ( PF01068 ) ATP-dependent DNA ligase domain
• ( PF01331 ) mRNA capping enzyme, catalytic domain
• ( PF03919 ) mRNA capping enzyme, C-terminal domain

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00760200

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_08901.1	9.997093137033517e-262	hypothetical protein (505 aa)
Oxytricha	Contig1451.1.g15	2.000470901975128e-28	mRNA capping enzyme, catalytic domain
SGD	YGL130W	0.000000000000004001928599951003	CEG1 Alpha (guanylyltransferas e) subunit of the mRNA capping enzyme, a heterodimer (the ot her subunit is CET1, an RNA 5- triphosphatase) involved in ad ding the 5 cap to mRNA; the ma mmalian enzyme is a single bif unctional polypeptide
WormBase	WBGene00000466	0.00000000002000577768187062	locus:cel-1 mRNA-capping enz yme status:Confirmed UniPr ot:Q17607 protein_id:CAA9976 5.2

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00760200(coding)
ATGGGAGATTTTCAAATTCTTTTGCATAGGCCTGGTAATGAAGTCATTATGGGAGAAGAA
TTTAACTACATTTAAGGATACTTGAATGAATTTAAAAAAGAAATGTTGATTGAAAATAAA
ATAACAGATCCAAGAAAAATAGAAAGAATTGATTTTATTGGTGCTTAACCTGTTTCAATG
AGAAATAGTCATGCTGATAGGATAAGAGAAGAAAGAGATTAAGCAGATATTAGCTATATT
GTTTGTGAGAAAACAGATGGTGTAAGATATATAATGGTAATTACAAATAATGGTTATTGC
TACTTAACAGGAAGAAATACCTCTACTGATTCTGAAAATAAATATAAGCTAAACTAAATC
AATGTTTAGTTAAATAAGCAACTATTCATTGATGAAAATGATGATGAAGAGGAGAATTTG
CAAATTTTAGAAATTTTTGATGGAGAATTAGTTTTAGACAAAAAAGGTGACAATTACTAT
TTAAAATATTTAGTTTTTGATTGCTTAGTTCATTTTGGAGAGAAGGTTTCTAATATTGAT
TATTTAAATCGTCTCACAAATGCATTATACTTTGTGCAATACAATAATAGTCTCTATGAG
ATTAATGGAGAGGAACTGCCAAAACCTTAGCCATTTTGTGAATTTAAAGCTAAAGCTCTG
TCTTAATTTTTAGAAACAGGAGAGACTGATAATTTTGAAGATTCAGAAAATGATCTTGTT
ATTTCGATATGTGTTAAAGATTTTTTCAAAATAAAATACTGCAACTACTTATTTGATAAT
TACATACCTTCTCTTCCTCATCACAATGATGGTTTGATTTTCACTAAAAATAACTCAATT
TATAAACCAGGAACTGACGAAAATATAATTAAATGGAAGCCTCCATCAATGAATACAATA
GACTTTCTTCTAGTGGCAAACTAAGACAATATATTATGCGGTATTGACGAAAAAAAAAGC
GATGGAAATTATCTTCTATAATCAAGAGTTATAGATTTATATGTTATGGATAACAATTTG
GAGAGAAAAAATTATGAAATAACATTTTTTGATTTTATGATTGTAGACCCAGACTTTTTC
GAAGAAGTTATTCAAAAAACAAGTGAAAAAGAAGGTGCCAAAGGTGTTGTTGCAGAATGC
AAGTGGATTGATTTGGATTAAGATAAGGGAGAAATAATCAAGAAAATTTATACAAGTGAC
ACTGATAAAATATTAGTTTTACCAGAATTTCCAGATGATAGCAATTAAGATGATAATCGT
AAATGGATAGCTAGCTAAAAATAAACTTATAAAGAGAATAAATTCTCTAAAGGATGGGGT
TTTGATAGATATAGATTAGATAAAAACTTTTCAAATAATAAAAAAATAGCTAAAGATATT
GTTTCTTCAATAAAAGAGAATCTGGATTCTAAGGCTCTTATGCAAAGATTGATGCCTAAT
TAACATCAAAATTCTAACATGGGTAATCCTAATCTTGAACCAAGTATACAAAAAAAATAA
AAAAGATGA

>TTHERM_00760200(protein)
MGDFQILLHRPGNEVIMGEEFNYIQGYLNEFKKEMLIENKITDPRKIERIDFIGAQPVSM
RNSHADRIREERDQADISYIVCEKTDGVRYIMVITNNGYCYLTGRNTSTDSENKYKLNQI
NVQLNKQLFIDENDDEEENLQILEIFDGELVLDKKGDNYYLKYLVFDCLVHFGEKVSNID
YLNRLTNALYFVQYNNSLYEINGEELPKPQPFCEFKAKALSQFLETGETDNFEDSENDLV
ISICVKDFFKIKYCNYLFDNYIPSLPHHNDGLIFTKNNSIYKPGTDENIIKWKPPSMNTI
DFLLVANQDNILCGIDEKKSDGNYLLQSRVIDLYVMDNNLERKNYEITFFDFMIVDPDFF
EEVIQKTSEKEGAKGVVAECKWIDLDQDKGEIIKKIYTSDTDKILVLPEFPDDSNQDDNR
KWIASQKQTYKENKFSKGWGFDRYRLDKNFSNNKKIAKDIVSSIKENLDSKALMQRLMPN
QHQNSNMGNPNLEPSIQKKQKR

>TTHERM_00760200(gene)
ATGGGAGATTTTCAAATTCTTTTGCATAGGCCTGGTAATGAAGTCATTATGGGAGAAGAA
TTTAACTACATTTAAGGATACTTGAATGAATTTAAAAAAGAAATGTTGATTGAAAATAAA
ATAACAGATCCAAGAAAAATAGAAAGAATTGATTTTATTGGTGCTTAACCTGTTTCAATG
AGAAATAGTCATGCTGATAGGATAAGAGAAGAAAGAGATTAAGCAGATATTAGCTATATT
GTTTGTGAGAAAACAGATGGTGTAAGATATATAATGGTAATTACAAATAATGGTTATTGC
TACTTAACAGGAAGAAATACCTCTACTGATTCTGAAAATAAATATAAGCTAAACTAAATC
AATGTTTAGTTAAATAAGCAACTATTCATTGATGAAAATGATGATGAAGAGGAGAATTTG
CAAATTTTAGAAATTTTTGATGGAGAATTAGTTTTAGACAAAAAAGGTGACAATTACTAT
TTAAAATATTTAGTTTTTGATTGCTTAGTTCATTTTGGAGAGAAGGTTTCTAATATTGAT
TATTTAAATCGTCTCACAAATGCATTATACTTTGTGCAATACAATAATAGTCTCTATGAG
ATTAATGGAGAGGAACTGCCAAAACCTTAGCCATTTTGTGAATTTAAAGCTAAAGCTCTG
TCTTAATTTTTAGAAACAGGAGAGACTGATAATTTTGAAGATTCAGAAAATGATCTTGTT
ATTTCGATATGTGTTAAAGATTTTTTCAAAATAAAATACTGCAACTACTTATTTGATAAT
TACATACCTTCTCTTCCTCATCACAATGATGGTTTGATTTTCACTAAAAATAACTCAATT
TATAAACCAGGAACTGACGAAAATATAATTAAATGGAAGCCTCCATCAATGAATACAATA
GACTTTCTTCTAGTGGCAAACTAAGACAATATATTATGCGGTATTGACGAAAAAAAAAGC
GATGGAAATTATCTTCTATAATCAAGAGTTATAGATTTATATGTTATGGATAACAATTTG
GAGAGAAAAAATTATGAAATAACATTTTTTGATTTTATGATTGTAGACCCAGACTTTTTC
GAAGAAGTTATTCAAAAAACAAGTGAAAAAGAAGGTGCCAAAGGTGTTGTTGCAGAATGC
AAGTGGATTGATTTGGATTAAGATAAGGGAGAAATAATCAAGAAAATTTATACAAGTGAC
ACTGATAAAATATTAGTTTTACCAGAATTTCCAGATGATAGCAATTAAGATGATAATCGT
AAATGGATAGCTAGCTAAAAATAAACTTATAAAGAGAATAAATTCTCTAAAGGATGGGGT
TTTGATAGATATAGATTAGATAAAAACTTTTCAAATAATAAAAAAATAGCTAAAGATATT
GTTTCTTCAATAAAAGAGAATCTGGATTCTAAGGCTCTTATGCAAAGATTGATGCCTAAT
TAACATCAAAATTCTAACATGGGTAATCCTAATCTTGAACCAAGTATACAAAAAAAATAA
AAAAGATGA