Identifiers and Description

Gene Model Identifier

TTHERM_00784290

Standard Name

CDK18 (Cyclin-Dependent Kinase 18)

Aliases

PreTt25533 | 131.m00106 | 3813.m01608

Description

cyclin-dependent kinase-like Serine/Threonine kinase family protein; Protein kinase domain containing protein; sequence similarity to the CDC2 subfamily of the protein kinase CDK family; involved in nuclear formation

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• protein kinase activity (IEA) | GO:0004672
• ATP binding (IEA) | GO:0005524
• protein tyrosine kinase activity (IEA) | GO:0004713

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.6%

TetraMine Data

TTHERM_00784290

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_11413.1	2.998986826334339e-156	protein kinase domain-containi ng protein (337 aa)
Oxytricha	Contig5189.0.g91	2.999467474389571e-105	Protein kinase domain
WormBase	WBGene00000405	5.000356947592888e-100	locus:cdk-1 Cyclin-dependent kinase 1 status:Confirmed UniProt:P34556 protein_id:C AA81590.1
DictyBase	DDB_G0272813	1.0003391709219401e-98	cdk1 on chromosome: 2 position 2216835 to 2217926
SGD	YBR160W	3.000425225396195e-97	CDC28 Catalytic subunit of the main cell cycle cyclin-depend ent kinase (CDK); alternately associates with G1 cyclins (CL Ns) and G2/M cyclins (CLBs) wh ich direct the CDK to specific substrates
Stentor Coeruleus	SteCoe_3497	8.408597124803643e-50

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,
2. Ref:SUPR000263

Sequences

>TTHERM_00784290(coding)
ATGGCAACTAATATTTTACAATCTTAAGTAAGCTTAGGTCACTAGGAAGATAAAAAATAA
TGCTTTAACGAAATTCCTGATAGGTTTAAATGCTTACAAAAAATTGGAGAGGGAACCTAT
GGTATTGTTTACAAAGGATTTGATACTTAAACCAACACACAAGTAGCTATTAAAAAAGTA
AAATTAGATTAGGAATAAGAAGGTATTCCTCAATCTGCCCTTAGAGAAATTTGTATATTA
AAGGATTTAAGCGACCATTAAAACATTGTCAAATTAAGAGATGTTATATATCAAATTGAG
GAAAGTAAACTATTTCTTGTTTTTGAATATGTTGACTATGATCTAAAGAAGTATTTGGAA
ACTATGAAACATTTAACATAACATGATATAAAATTAATAATGTATCAACTCTTAAACGGT
TTAGATTTTTGTCACTAAAGAAGAATCATTCATAGAGATATTAAACCCTAAAATATACTT
ATTGATAAGGCTGGAAACGTTAAAATAGCAGATTTTGGTCTGGCTAAAACTTTTTAAGTA
CCAAGCAAAACGCTCACTCATGAGGTAGAAACTCTTTGGTACAGACCACCTGAAATTTTA
TTGGGTGTAAAAACTTACTCCTTGGCTATAGATATGTGGAGTATTGGCTGCGTATTCTAT
GAATTGATGGAAAAAAAACCTTTATTTATAAGTGATTCAGAAATAGAAGCCATATTTAAA
ATCTTTTAATTTCATGGTACTCCCAATTCAGAAACATTTTAAGGATTAGAAGATTATCCT
TACTTTAAGTCTACATTCCCTCGTTTCCATGCTTAAGATCCTTTTATAGTATTTAAAAAT
TTAGAAAATGATGCTCGCGACTTACTTATGTAAATGATAGCCCTTAATCCTTTAGACAGA
ATATCAGTAAAGTAAGCTCTTTTGCACCCATATTTCGATAGCCTTACAGAAAGCGAAAAG
ACTGCATATAACTAATATAATACCAACCAATACATGAAATTTTTTTCAATTTGA

>TTHERM_00784290(protein)
MATNILQSQVSLGHQEDKKQCFNEIPDRFKCLQKIGEGTYGIVYKGFDTQTNTQVAIKKV
KLDQEQEGIPQSALREICILKDLSDHQNIVKLRDVIYQIEESKLFLVFEYVDYDLKKYLE
TMKHLTQHDIKLIMYQLLNGLDFCHQRRIIHRDIKPQNILIDKAGNVKIADFGLAKTFQV
PSKTLTHEVETLWYRPPEILLGVKTYSLAIDMWSIGCVFYELMEKKPLFISDSEIEAIFK
IFQFHGTPNSETFQGLEDYPYFKSTFPRFHAQDPFIVFKNLENDARDLLMQMIALNPLDR
ISVKQALLHPYFDSLTESEKTAYNQYNTNQYMKFFSI

>TTHERM_00784290(gene)
ATGGCAACTAATATTTTACAATCTTAAGTAAGCTTAGGTCACTAGGAAGATAAAAAATAA
TGCTTTAACGAAATTCCTGATAGGTTTAAATGCTTACAAAAAATTGGAGAGGGAACCTAT
GGTATTGTTTACAAAGGATTTGATACTTAAACCAACACACAAGTAGCTATTAAAAAAGTA
AAATTAGATTAGGAATAAGAAGGTATTCCTCAATCTGCCCTTAGAGAAATTTGTATATTA
AAGGATTTAAGCGACCATTAAAACATTGTCAAGTAATTTTTTATATTTTATTAATTGATT
ATTATTTTCTTTTCAGCATTTCTTTGCATCATAGCTATGAAAGATATATTTAAATTATAT
TCATTAAATTATGTTCCTTATTAGATTAAGAGATGTTATATATCAAATTGAGGAAAGTAA
ACTATTTCTTGTTTTTGAATATGTTGACTATGATCTAAAGAAGTATTTGGAAACTATGAA
ACATTTAACATAACATGATATAAAAGTAATTTTTTATTACAAGTTGTTAAATTTATTATT
ACTAATTTTTAAAATTTAAAACTAGTTAATAATGTATCAACTCTTAAACGGTTTAGATTT
TTGTCACTAAAGAAGAATCATTCATAGAGATATTAAACCCTAAAATATACTTATTGATAA
GGCTGGAAACGTTAAAATAGCAGATTTTGGTCTGGCTAAAACTTTTTAAGTACCAAGCAA
AACGCTCACTCATGAGGTAGAAACTCTTTGGTACAGACCACCTGAAATTTTATTGGGTGT
AAAAACTTACTCCTTGGCTATAGATATGTGGAGTATTGGCTGCGTATTCTATGAATTGAT
GGAAAAAAAACCTTTATTTATAAGTGATTCAGAAATAGAAGCCATATTTAAAATCTTTTA
ATTTCATGGTACTCCCAATTCAGAAACATTTTAAGGATTAGAAGATTATCCTTACTTTAA
GTCTACATTCCCTCGTTTCCATGCTTAAGATCCTTTTATAGTATTTAAAAATTTAGAAAA
TGATGCTCGCGACTTACTTATGTAAATGATAGCCCTTAATCCTTTAGACAGAATATCAGT
AAAGTAAGCTCTTTTGCACCCATATTTCGATAGCCTTACAGAAAGCGAAAAGACTGCATA
TAACTAATATAATACCAACCAATACATGAAATTTTTTTCAATTTGA