Identifiers and Description

Gene Model Identifier

TTHERM_00066860

Standard Name

CDK17 (Cyclin-Dependent Kinase 17)

Aliases

PreTt13176 | 4.m00575 | 3707.m00213

Description

cyclin-dependent kinase-like Serine/Threonine kinase family protein; Protein kinase domain containing protein; Sequence similarity to the PITSLRE subfamily of the protein kinase CDK family

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• protein tyrosine kinase activity (IEA) | GO:0004713
• protein kinase activity (IEA) | GO:0004672
• ATP binding (IEA) | GO:0005524

Biological Process

• protein phosphorylation (IEA) | GO:0006468

Domains

• ( PF01163 ) RIO1 family
• ( PF00069 ) protein kinase domain
• ( PF07714 ) protein tyrosine kinase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.9%

TetraMine Data

TTHERM_00066860

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02086.1	9.997093137033517e-262	protein kinase domain-containi ng protein (425 aa)
Oxytricha	Contig21786.0.g114	7.00091582959949e-118	Protein kinase domain
DictyBase	DDB_G0283279	9.003233894748109e-95	cdk11 on chromosome: 4 positio n 446640 to 447716
WormBase	WBGene00015203	3.9984352235938583e-87	Putative serine/threonine-prot ein kinase B0495.2 status:Pa rtially_confirmed UniProt:Q0 9437 protein_id:CCD61471.1
SGD	YKL139W	4.000989088096131e-71	CTK1 Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-m RNA 3 end processing, and ribo somal protein Rps2p to increas e translational fidelity; simi lar to the Drosophila dCDK12 a nd human CDK12 and probably CD K13
Stentor Coeruleus	SteCoe_18197	2.6786369618080778e-33

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16933976: Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, Majoros WH, Farzad M, Carlton JM, Smith RK, Garg J, Pearlman RE, Karrer KM, Sun L, Manning G, Elde NC, Turkewitz AP, Asai DJ, Wilkes DE, Wang Y, Cai H, Collins K, Stewart BA, Lee SR, Wilamowska K, Weinberg Z, Ruzzo WL, Wloga D, Gaertig J, Frankel J, Tsao CC, Gorovsky MA, Keeling PJ, Waller RF, Patron NJ, Cherry JM, Stover NA,
2. Ref:SUPR000262

Sequences

>TTHERM_00066860(coding)
ATGTCTGATTAGCAAATAGATAAACAAAGAGAAGAAGCTCACTTTAATGAAAATGAGTCT
TCTGATTCTAACTTTGACCATATAGAAGATAATGAATAGGATGAATAAAAAAATGAAATT
AATTTAAATTTAGATGATGAAGAAAGAAAAATTTTACGTAAGCATTCTTAAGAATTATCA
GCGGAAAAGAAATTATCATTATTACGTAAAAGGAAAATATGCGGTCTTTTAGAAGGATGT
GATTCTGTAGATAATTATTAAAAATTAAATAAAATTCATGAAGGTGTTTATGGTGTTGTA
TATAGAGCTGTCGATAAATTAACTGGAGAAATTATAGCTATTAAAAAAACCAAAATAGAT
CGCAAAAAAGAAAAGGAAGGATTTCCTATCACTTCAATCAGAGAATTTAACATTCTAATG
GCTCTTAGACATGAAAATATAGTAGCTGTAAAAAGAGTTGTGATGGGTACAGATCTAGAT
TCTATATATATGATTATGGAGTACATGGAGCATGAGTTGAAGGATGTTATTGAGAATCAT
CATGATGAATTTTAGGAACCATAAATTAAAAGTCTTGTCTAGTAGCTACTTTTAGGAATG
GATTTTTTATAAAAAAAGAAGATTATGCATAGAGATTTAAAAACTTCAAATATTTTGTAT
AATAATAAGGGGTAATTAAAAATTTGTGATTTTGGTTTAGGTAGAAGATGGCAAGGTAAT
AAGCCTTACACCTTAAATGTAGTTACTATGTGGTATCGTGCACCTGAAGTATTACTAGGC
TAAGATAAGTATACAACTGCTCTAGATATGTGGAGTGTGGGTTGCATTTTTGGTGAACTA
ATAACTAAAGATTAGCTATTTAAAGGAAAAAATGAAACAAACTAAATTGAGTGTATATTC
AATGCCATGGGAGGTCCCACAGAGCGTTCATGGCCTGGCTGGACTGAGTTCAAACATTCT
AAGCTTTTTAAAGATAGAAATTACCCATCAGAATGTACCTTGAATGAAAAAATAGGGAAT
AGAATATCATAAACAGGTTACAAATTATTGTGCTAAATGCTTACTTTAAACCCTAAAGAG
CGTATTACTGCTACAAAAGCACTTCAAGATCCTTGGTTTAAAGAAGAACCTCTTCCTGCA
AAACTAGAAGATATGCCTAAATTCAAACCATTAAATGAAATATCGAGAGAAGAAAGAAAA
AAGTTAAAATTAAATAATTAGCAAGCTTAACAGTAGGCTTAACAATCTCCAATTAAAGAG
TGA

>TTHERM_00066860(protein)
MSDQQIDKQREEAHFNENESSDSNFDHIEDNEQDEQKNEINLNLDDEERKILRKHSQELS
AEKKLSLLRKRKICGLLEGCDSVDNYQKLNKIHEGVYGVVYRAVDKLTGEIIAIKKTKID
RKKEKEGFPITSIREFNILMALRHENIVAVKRVVMGTDLDSIYMIMEYMEHELKDVIENH
HDEFQEPQIKSLVQQLLLGMDFLQKKKIMHRDLKTSNILYNNKGQLKICDFGLGRRWQGN
KPYTLNVVTMWYRAPEVLLGQDKYTTALDMWSVGCIFGELITKDQLFKGKNETNQIECIF
NAMGGPTERSWPGWTEFKHSKLFKDRNYPSECTLNEKIGNRISQTGYKLLCQMLTLNPKE
RITATKALQDPWFKEEPLPAKLEDMPKFKPLNEISREERKKLKLNNQQAQQQAQQSPIKE

>TTHERM_00066860(gene)
ATGTCTGATTAGCAAATAGATAAACAAAGAGAAGAAGCTCACTTTAATGAAAATGAGTCT
TCTGATTCTAACTTTGACCATATAGAAGATAATGAATAGGATGAATAAAAAAATGAAATT
AATTTAAATTTAGATGATGAAGAAAGAAAAATTTTACGTAAGCATTCTTAAGAATTATCA
GCGGAAAAGAAATTATCATTATTACGTAAAAGGAAAATATGCGGTCTTTTAGAAGGATGT
GATTCTGTAGATAATTATTAAAAATTAAATAAAATTCATGAAGGTGTTTATGGTGTTGTA
TATAGAGCTGTCGATAAATTAACTGGAGAAATTATAGCTATTAAAAAAACCAAAATAGAT
CGCAAAAAAGAAAAGGAAGGATTTCCTATCACTTCAATCAGAGAATTTAACATTCTAATG
GCTCTTAGACATGAAAATATAGTAGGTAAACCTTTATTTTATATAATAAGTTGCTTTTTT
ACAAGAATAAATTCAAATTTTAAGTTTTCAAAATAAAAAAATCGCGTCTATTAAAATTAT
ATCAATAAATATCATGATTGATATATAAATAAATATAAGAAAATGAATGAATAATTATAT
TTATGAAGTCTATTTTCTATTTATTTCAATTAATTTTTTTATAAATTTATATAAAGATTT
TTTTAAAATATAGCTGTAAAAAGAGTTGTGATGGGTACAGATCTAGATTCTATATATATG
ATTATGGAGTACATGGAGCATGAGTTGAAGGATGTTATTGAGAATCATCATGATGAATTT
TAGGAACCATAAATTAAAAGTCTTGTCTAGTAGCTACTTTTAGGAATGGATTTTTTATAA
AAAAAGAAGATTATGCATAGAGATTTAAAAACTTCAAATATTTTGTATAATAATAAGGGG
TAATTAAAAATTTGTGATTTTGGTTTAGGTAGAAGATGGCAAGGTAATAAGCCTTACACC
TTAAATGTAGTTACTATGTGGTATCGTGCACCTGAAGTATTACTAGGCTAAGATAAGTAT
ACAACTGCTCTAGATATGTGGAGTGTGGGTTGCATTTTTGGTGAACTAATAACTAAAGAT
TAGCTATTTAAAGGAAAAAATGAAACAAACTAAATTGAGTGTATATTCAATGCCATGGGA
GGTCCCACAGAGCGTTCATGGCCTGGCTGGACTGAGTTCAAACATTCTAAGCTTTTTAAA
GATAGAAATTACCCATCAGAATGTACCTTGAATGAAAAAATAGGGAATAGAATATCATAA
ACAGGTTACAAATTATTGTGCTAAATGCTTACTTTAAACCCTAAAGAGCGTATTACTGCT
ACAAAAGCACTTCAAGATCCTTGGTTTAAAGAAGAACCTCTTCCTGCAAAACTAGAAGAT
ATGCCTAAATTCAAACCATTAAATGAAATATCGAGAGAAGAAAGAAAAAAGTTAAAATTA
AATAATTAGCAAGCTTAACAGTAGGCTTAACAATCTCCAATTAAAGAGTGA