Identifiers and Description

Gene Model Identifier

TTHERM_00522490

Standard Name

ATG8 (AuTophaGy related 8)

Aliases

PreTt12364 | 65.m00182 | 3717.m00061

Description

ubiquitin-like protein whose conjugation target is phosphatidylethanolamine (PE); required for formation of autophagosomes; Atg8p-PE is anchored to membranes; one of two ATG8 genes in Tetrahymena, see TTHERM_00037460

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF04110 ) Autophagy protein Apg12
• ( PF02991 ) Microtubule associated protein 1A/1B, light

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00522490

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_12857.1	3.9983507938127826e-75	hypothetical protein (123 aa)
Oxytricha	Contig22034.0.g103	3.998693556225637e-29	Autophagy protein Atg8 ubiquit in like
WormBase	WBGene00002980	8.000124778438792e-23	locus:lgg-1 Protein lgg-1 status:Confirmed UniProt:Q09 490 protein_id:CCD66037.1
DictyBase	DDB_G0286191	3.0002687256732656e-20	atg8 on chromosome: 4 position 4321108 to 4321704
SGD	YBL078C	1.9999391735788327e-19	ATG8 Component of autophagosom es and Cvt vesicles; undergoes conjugation to phosphatidylet hanolamine (PE); Atg8p-PE is a nchored to membranes, is invol ved in phagophore expansion, a nd may mediate membrane fusion during autophagosome formatio n
Stentor Coeruleus	SteCoe_19415	0.0000000000006914400106940203

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00522490(coding)
ATGGACTCAAATAAACGTTATAAAGATCTTCTTAGTGAAGATTAAAGAAAATCAGAATGC
GAAAATATAAGAAAGAATTATCCTGATAAGATTCCCCTCATTATTGAGAAGCATCCTAAA
TCTAAATTAGAATAAATAGATAGGACAAAATTCTTAATTCTTGAAAAGCTTAGAGTTTAT
CAAGTAAACACAATTATACGTAGAAAAATGAGTCTCAATAAAGTAGATGCTCTCTATCTC
TTTGTTAATGATAATATTCTTTTAAGAGGAGATTAATGCTTAAAAGATGTTTATGAAAAA
TACAAAGATTCAGATGGATTTATTTATCTTTCTTACTGCGAATATAGTTCTTTTGGTAAG
AATATCTGA

>TTHERM_00522490(protein)
MDSNKRYKDLLSEDQRKSECENIRKNYPDKIPLIIEKHPKSKLEQIDRTKFLILEKLRVY
QVNTIIRRKMSLNKVDALYLFVNDNILLRGDQCLKDVYEKYKDSDGFIYLSYCEYSSFGK
NI

>TTHERM_00522490(gene)
ATGGACTCAAATAAACGTTATAAAGATCTTCTTAGTGAAGATTAAAGAAAATCAGAATGC
GAAAATATAAGAAAGAATTATCCTGATAAGATTCCCCTCATTATTGAGAAGCATCCTAAA
TCTAAATTAGAATAAATAGATAGGACAAAGTAAAATATTTTTTAAGTTCCAATTCAATTA
TGCGGTTAGCTAAATTAAAATACATATTTAACAAAAATTTATTTGATGGAGTATTAATAG
CTCTATTTTATAATAATTGTATTAAAGTGCACATAATTTGAAGTTTCATTTTAGCAATTT
AGAAAATTATTTGGATATAAATTGGATTAATTTATTTTTTAACATTTTAAATAGATTCTT
AATTCTTGAAAAGCTTAGAGTTTATCAAGTAAACACAATTATACGTAGAAAAATGAGTCT
CAATAAAGTAGATGCTCTCTATCTCTTTGTTAATGATAATATTCTTTTAAGAGGAGGTAT
TTCATAAACTTAAATAATATAAATATAAGATTATTAGATTTTTTTAAAGAATCAAATTTA
TTAATGATTTTATTATATCCATAATTTCAATTTTTCTTAAATAAAATATGGTTTAAAGAT
AAATAATTTTAACAATAGATTAATGCTTAAAAGATGTTTATGAAAAATACAAAGATTCAG
ATGGATTTATTTATCTTTCTTACTGCGAATATAGTTCTTTTGGTAAGAATATCTGA