Identifiers and Description

Gene Model Identifier

TTHERM_00494030

Standard Name

ATG5 (AuTophaGy 5)

Aliases

PreTt04240 | 61.m00227 | 3711.m00074

Description

Autophagy protein; involved in programmed nuclear degradation (autophagy)

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Biological Process

• autophagy (ISS) | GO:0006914 | Ref:22366125

Domains

• ( PF04106 ) Autophagy protein Apg5

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.8%

TetraMine Data

TTHERM_00494030

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_13000.1	9.001310321615282e-163	hypothetical protein (320 aa)
Oxytricha	Contig14975.0.g34	2.0004286606204839e-16	Autophagy protein Apg5
SGD	YPL149W	0.000000009996807949091551	ATG5 Conserved protein involve d in autophagy and the Cvt pat hway; undergoes conjugation wi th Atg12p to form a complex in volved in Atg8p lipidation; co njugated Atg12p also forms a c omplex with Atg16p that is ess ential for autophagosome forma tion
WormBase	WBGene00022152	0.0000007997233352734267	locus:atg-5 status:Confirmed protein_id:CDM63580.1
DictyBase	DDB_G0289881	0.0000020007268868677913	atg5 on chromosome: 5 position 3433996 to 3435424

General Information

No Data fetched for General Information

Associated Literature

1. Ref:22366125: Liu ML, Yao MC (2012) Role of ATG8 and autophagy in programmed nuclear degradation in Tetrahymena thermophila. Eukaryotic cell 11(4):494-506

Sequences

>TTHERM_00494030(coding)
ATGGCAGAGGAACAAAAATAAACAGATTTTGAAAGAGATTAAAAAGAAATTAGGTCTTTA
ATATGGCAAAATAAAATCCCTGTTAAAATTAAATTAGACCCAGAACAAAATAGCAATAAT
GAGGAACCATTTCCTCTTTATATGTTCTTTTAAAGAGTTCACCTACCAGTATTTTATTAT
GAATAAATTCATGAGTACTTTGAAAAATTTGCTCCTGTTCCAAGAAATTAGGATGATATA
TGGTTAGAATGGAATAATAAACCAATTGCTTGGAATTTACCCTTTGGAGTGACTTTTGAT
TTAAATTATTAGGACCCATCTATGAAAGGAGAATTAGGTGATGATGATAGTTTTGATTTA
GGAATTTAAGAAATTCCTCCACCATTTATTCCTTAAAATATAATCTTGCATTATGGTCCT
TGCACTATTTCTAATGACTATACTCCTATTCCAAGCATCCCTGGCAAAACCGTATTAGAT
ATAGCAAAAAAAAGTTTTAGGTTTGCCCTTAAAGAATCACTTCATATTAGATTTGATAGC
GATACTATTCTTATGTAAATGGAAGCAGAAAAATAAAACGAATTATGGGAATCTTATAAA
AACCTCAACCAAAACACCTTTTTTAGCATTTTAGATTAGATATTTTAGTTGAAAAATCAT
TTGTAAAATAACAAAGCAATTAAATTGCCTGTAAGAGTGTATATAGAAGGTTATATAGGT
CGTATATAACTCTCTCATCAAATAGATTCTGAAAATGATACTTTAGGCGATTTTCTAACA
AAATATTTCCCTAAAATTTTAAAATAAACAGATACTGCCTTTGAAATAATTAATGATAAT
TACAAAAACTTCAAAGTAATATGCAATGGAATTGTTTGTAACTTAAACATGCCTTTACTT
TACTTTTACAAATATTTCTCTCATTATGATGGCTTCACTTATCTATGTATATAAAAATGA

>TTHERM_00494030(protein)
MAEEQKQTDFERDQKEIRSLIWQNKIPVKIKLDPEQNSNNEEPFPLYMFFQRVHLPVFYY
EQIHEYFEKFAPVPRNQDDIWLEWNNKPIAWNLPFGVTFDLNYQDPSMKGELGDDDSFDL
GIQEIPPPFIPQNIILHYGPCTISNDYTPIPSIPGKTVLDIAKKSFRFALKESLHIRFDS
DTILMQMEAEKQNELWESYKNLNQNTFFSILDQIFQLKNHLQNNKAIKLPVRVYIEGYIG
RIQLSHQIDSENDTLGDFLTKYFPKILKQTDTAFEIINDNYKNFKVICNGIVCNLNMPLL
YFYKYFSHYDGFTYLCIQK

>TTHERM_00494030(gene)
ATGGCAGAGGAACAAAAATAAACAGATTTTGAAAGAGATTAAAAAGAAATTAGGTCTTTA
ATATGGCAAAATAAAATCCCTGTTAAAATTAAATTAGACCCAGAACAAAATAGCAATAAT
GAGGAACCATTTCCTCTTTATATGTTCTTTTAAAGAGTTCACCTACCAGTATTTTATTAT
GAATAAATTCATGAGTACTTTGAAAAATTTGCTCCTGTTCCAAGAAATTAGGATGATATA
TGGTTAGAATGGAATAATAAACCAATTGCTTGGAATTTACCCTTTGGAGTGACTTTTGAT
TTAAATTATTAGGACCCATCTATGAAAGGAGAATTAGGTGATGATGATAGTTTTGATTTA
GGAATTTAAGAAATTCCTCCACCATTTATTCCTTAAAATATAATCTTGCATTATGGTCCT
TGCACTATTTCTAATGACTATACTCCTATTCCAAGCATCCCTGGCAAAACCGTATTAGAT
ATAGCAAAAAAAAGTTTTAGGTTTGCCCTTAAAGAATCACTTCATATTAGATTTGATAGC
GATACTATTCTTATGTAAATGGAAGCAGAAAAATAAAACGAATTATGGGAATCTTATAAA
AACCTCAACCAAAACACCTTTTTTAGCATTTTAGATTAGATATTTTAGTTGAAAAATCAT
TTGTAAAATAACAAAGCAATTAAATTGCCTGTAAGAGTGTATATAGAAGGTTATATAGGT
CGTATATAACTCTCTCATCAAATAGATTCTGAAAATGATACTTTAGGCGATTTTCTAACA
AAATATTTCCCTAAAATTTTAAAATAAACAGATACTGCCTTTGAAATAATTAATGATAAT
TACAAAAACTTCAAAGTAATATGCAATGGAATTGTTTGTAACTTAAACATGCCTTTACTT
TACTTTTACAAATATTTCTCTCATTATGATGGCTTCACTTATCTATGTATATAAAAATGA