Identifiers and Description

Gene Model Identifier

TTHERM_00455300

Standard Name

APM3 (Adaptor Protein complex Medium subunit 3 )

Aliases

PreTt20259 | 53.m00161 | 3712.m00022 | APM1B

Description

Adaptor complex, medium subunit family protein

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• membrane coat (IEA) | GO:0030117
• clathrin adaptor complex (IEA) | GO:0030131
• AP-1 adaptor complex (ISS) | GO:0030121 | Ref:16276403

Molecular Function

• protein binding (IEA) | GO:0005515

Biological Process

• vesicle-mediated transport (IEA) | GO:0016192
• intracellular protein transport (IEA) | GO:0006886
• vesicle-mediated transport (ISS) | GO:0016192 | Ref:16276403

Domains

• ( PF01217 ) Clathrin adaptor complex small chain
• ( PF00928 ) Adaptor complexes medium subunit family

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 11.9%

TetraMine Data

TTHERM_00455300

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_13727.1	9.997093137033517e-262	adaptor complexes medium subun it protein (440 aa)
Oxytricha	Contig21523.0.g45	3.999622461503957e-161	Adaptor complexes medium subun it family
DictyBase	DDB_G0289247	2.0000633521090825e-149	apm1 on chromosome: 5 position 2536641 to 2538194
WormBase	WBGene00000150	2.000893364583308e-148	locus:apm-1 status:Confirmed UniProt:O01755 protein_id :CCD65442.1
SGD	YPL259C	2.000808864924972e-124	APM1 Mu1-like medium subunit o f the clathrin-associated prot ein complex (AP-1); binds clat hrin; involved in clathrin-dep endent Golgi protein sorting
Stentor Coeruleus	SteCoe_31620	4.408531331463226e-71

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16276403: Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP (2005) Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. PLoS genetics 1(5):e52

Sequences

>TTHERM_00455300(coding)
ATGTCTGGAATTTCAGGAATATTTATCCTTAATAATAAAGGAAGAGTTATTATTCAAAGA
GTTTATCGTGCTGATTTACAAGTGCATGTAATTGAAACATTTAATAAAAAATTAGTTGAA
TTTGATGAATTCAATCAAAAGCCTATTGTCTAAGATGAGTTTGGAAATACTTACATTTAT
AGAAATCACAACAATTTAACTTTTTTGATCATTACAAGAAGAAATACTAATGTTATGATG
GTTTTTGCCTTCTTGTATTAGTTTATCGAAGTTTTAGTTCATTATTTTAAAGAGCTGGAA
GAAGAATCTGTCAGAGATAATTTTGTAGTAATTTATGAATTATTAGATGAAGTTTTAGAT
AATGGATATCCTCAAATTACTGACTGCAAAAACTTATCTGAATTTATTAAAACAGAAAGT
CATGAGCTAGTTAAAGATTCTTTCTTTGGAGGAAAAGAAAAAAAAGAAGAAAATTTATCA
AAGTATGCAACTATGTCAACAGCAGCTATTTCATGGAGACCTGAAGGAATTAAATATAAA
AAGAATGAAATCTTCTTAGATGTTTATGAAAAGCTAAATATGCTAATTGGTAAAACTGGT
AACGTTATTGAAGCTGAAATCATAGGTAATGTAGTTGCAAATTCTATGCTTTCAGGTATG
CCTGACTGTAAGCTCGGCTTAAATGATAAAGCATATTTTGAAGCTATAGGTAGATCCACA
AATGCAAGAACAATTAACTTTGAAGATATGAAATTCCATTAATGTGTTCGTTTATCTAAA
TTTGAAAATGAAAGGCTCATTACTTTTATTCCTCCTGATGGTGAATTCGAACTGATTTCA
TATAGAATTCCTGTTCAAATTAAGCCTCTCTTCTAAGTGGATGTAATTATTACCCAACCT
AAACCAACTAAAATTGAAATAATGGTAAAAGCCAAGTCTAATTTTAAAGAGAAATCAACA
GCAAATGATGTCGACATATATATACCTGTTCCTGAAGATGTATAGAAACCAGAATTTAAG
TGTGCTTTTGGTAAATCAATCTGGGATTAAGGACGCGAAGCTATCAAATGGAGCTTCAAG
TAATTTGTTGGTCAAAAAGAATATATCATGTAATGCACTTTCAATTTACCCACAGTTGCT
TCTCCTGGTAGAGAAAAATATAAATAAGTACCTATTTCTATTAATTTCGAAATTCCATAT
TACACTGTTAGCGGCTTCTAAGTTAGATATCTTAAAGTTGAAGAGAGAAGTGGCTATAAT
GCACTTCCATGGGTTCGTTATGTAACTAAAAATGGCGATTACTAAATAAGAATGTTTTGA

>TTHERM_00455300(protein)
MSGISGIFILNNKGRVIIQRVYRADLQVHVIETFNKKLVEFDEFNQKPIVQDEFGNTYIY
RNHNNLTFLIITRRNTNVMMVFAFLYQFIEVLVHYFKELEEESVRDNFVVIYELLDEVLD
NGYPQITDCKNLSEFIKTESHELVKDSFFGGKEKKEENLSKYATMSTAAISWRPEGIKYK
KNEIFLDVYEKLNMLIGKTGNVIEAEIIGNVVANSMLSGMPDCKLGLNDKAYFEAIGRST
NARTINFEDMKFHQCVRLSKFENERLITFIPPDGEFELISYRIPVQIKPLFQVDVIITQP
KPTKIEIMVKAKSNFKEKSTANDVDIYIPVPEDVQKPEFKCAFGKSIWDQGREAIKWSFK
QFVGQKEYIMQCTFNLPTVASPGREKYKQVPISINFEIPYYTVSGFQVRYLKVEERSGYN
ALPWVRYVTKNGDYQIRMF

>TTHERM_00455300(gene)
ATGTCTGGAATTTCAGGAATATTTATCCTTAATAATAAAGGAAGAGTTATTATTCAAAGA
GTTTATCGTGCTGATTTACAAGTGCATGTAATTGAAACATTTAATAAAAAATTAGTTGAA
TTTGATGAATTCAATCAAAAGCCTATTGTCTAAGATGAGTTTGGAAATACTTACATTTAT
AGAAATCACAACAATTTAACTTTTTTGATCATTACAAGAAGAAATACTAATGTTATGATG
GTTTTTGCCTTCTTGTATTAGTTTATCGAAGTTTTAGTTCATTATTTTAAAGAGCTGGAA
GAAGAATCTGTCAGAGATAATTTTGTAGTAATTTATGAATTATTAGATGAAGTTTTAGAT
AATGGATATCCTCAAATTACTGACTGCAAAAACTTATCTGAATTTATTAAAACAGAAAGT
CATGAGCTAGTTAAAGGTAATTAATTTATCTCAAATAGCCTCAAGCTTATTTTACAGAAA
TATTAAAATCAATATTTCAAAAATAGAATTTAATTTGAAAATCATGATTGTGCAAATTTT
GATTTATTGTCACTCATAAAATGGCTTAAATCTTCTAAGCTAATTATTTATTTATATGAG
ATATTATTAATGATGTAAACTAATTAAATCATTTTTCATTTACAAAAATAGATTCTTTCT
TTGGAGGAAAAGAAAAAAAAGAAGAAAATTTATCAAAGTATGCAACTATGTCAACAGCAG
CTATTTCATGGAGACCTGAAGGAATTAAATATAAAAAGAATGAAATCTTCTTAGATGTTT
ATGAAAAGCTAAATATGCTAATTGGTAAAACTGGTAACGTTATTGAAGCTGAAATCATAG
GTAATGTAGTTGCAAATTCTATGCTTTCAGGTATGCCTGACTGTAAGCTCGGCTTAAATG
ATAAAGCATATTTTGAAGCTATAGGTAGATCCACAAATGCAAGAACAATTAACTTTGAAG
ATATGAAATTCCATTAATGTGTTCGTTTATCTAAATTTGAAAATGAAAGGCTCATTACTT
TTATTCCTCCTGATGGTGAATTCGAACTGATTTCATATAGGTAAAATCATTAAATGTCAT
TTAAATTATCTTATTTTAAAAATATAAAGAATTCCTGTTCAAATTAAGCCTCTCTTCTAA
GTGGATGTAATTATTACCCAACCTAAACCAACTAAAATTGAAATAATGGTAAAAGCCAAG
TCTAATTTTAAAGAGAAATCAACAGCAAATGATGTCGACATATATATACCTGTTCCTGAA
GATGTATAGAAACCAGAATTTAAGTGTGCTTTTGGTAAATCAATCTGGGATTAAGGACGC
GAAGCTATCAAATGGAGCTTCAAGTAATTTGTTGGTCAAAAAGAATATATCATGTAATGC
ACTTTCAATTTACCCACAGTTGCTTCTCCTGGTAGAGAAAAATATAAATAAGTACCTATT
TCTATTAATTTCGAAATTCCATATTACACTGTTAGCGGCTTCTAAGTTAGATATCTTAAA
GTTGAAGAGAGAAGTGGCTATAATGCACTTCCATGGGTTCGTTATGTAACTAAAAATGGC
GATTACTAAATAAGAATGTTTTGA