Identifiers and Description

Gene Model Identifier

TTHERM_01108620

Standard Name

APM2 (Adaptor Protein complex Medium subunit 2 )

Aliases

PreTt20393 | 238.m00043 | 3797.m00202 | APM1A

Description

Homolog of adaptor protein complex (AP-1) medium (mu) subunit; localized to internal structures in cell

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• clathrin adaptor complex (IEA) | GO:0030131
• AP-1 adaptor complex (ISS) | GO:0030121 | Ref:16276403

Molecular Function

• protein binding (IEA) | GO:0005515

Biological Process

• vesicle-mediated transport (IEA) | GO:0016192
• intracellular protein transport (IEA) | GO:0006886
• vesicle-mediated transport (ISS) | GO:0016192 | Ref:16276403

Domains

No Data fetched for Domains

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_01108620

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_06698.1	9.997093137033517e-262	adaptor complexes medium subun it protein (444 aa)
Oxytricha	Contig21523.0.g45	3.9994088109733696e-178	Adaptor complexes medium subun it family
DictyBase	DDB_G0289247	9.995404496431436e-166	apm1 on chromosome: 5 position 2536641 to 2538194
WormBase	WBGene00006829	3.0005183738819142e-162	locus:unc-101 AP-1 complex s ubunit mu-1-I status:Confirm ed UniProt:P35602 protein_ id:CAB05557.3
SGD	YPL259C	9.999875542736265e-136	APM1 Mu1-like medium subunit o f the clathrin-associated prot ein complex (AP-1); binds clat hrin; involved in clathrin-dep endent Golgi protein sorting
Stentor Coeruleus	SteCoe_1791	4.961148436415422e-78

General Information

No Data fetched for General Information

Associated Literature

1. Ref:16276403: Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP (2005) Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. PLoS genetics 1(5):e52

Sequences

>TTHERM_01108620(coding)
ATGCTTTATACATACAATTAACATTTGAAAAATAAAATCTTAGGAAGGAAAACAAACAAC
CAACTATAAAAAATTAAATAAAAATAATAAACAAATTAAGAAGTGAATAGATAAATAGAT
CTTGAATTTATTGTTTATCATTAATAGATTGAAGGTAAAAGCAAATAAATAAATAAGCAA
TTAATTAATAAATTAATAAGTAAATAAATAGTTAATACAAAATACAACTAAAATAGCATA
GAAATCATTTTTTAAAAATATTTTAAGAATTAGAAAGCAATGTCATCCTGTATTAGTACT
GGTATTTCAGCCATCTATATTTTAGATCATAAGGGAAGAGTTCTCATCACAAGATGTTAT
AAAGGTGATTTGCCTATTAACATTCATGATATTTTCAACAAGAAATTGCTTGAATATGAT
GAATTCTCAGTTAAGCCTATTTTGCGTGATAAGTATGGTCACTCTTTCTTCTATTTACAT
CATAATAATTTGATCTTCTTAGCAATTTCTAGAAAGAATACTAACTGCATGATGGTGTTC
AGCTTCTTGTACCAACTTATTTAAGTTTTAGTAGATTATTTTAAGGAATTAGAAGAGGAA
TCTGTACGTGATAATTTTGTTATTATTTATGAACTACTTGATGAAATGATGGATAATGGT
TATCCCCAAACCACTGACAATAAGATTCTTAAAGGATTGATAAAGACTGAATCTCATGAG
TTGAAAAAAGATTAAAAAAAGCCAAGCAAGAATAGTTCTTTGTCAATCGAAAACTAAGTA
GATGCAATTACAGGTGCAGTTACTTGGAGAAACAATGGTATTTCTTACAAAAAGAATGAA
GTCTTTTTGGATGTTATTGAAAAATTAAATATGTTAGTTTCTCATCAAGGTAATGTCATT
AAGTCAGAAATAGCTGGTTAAATTAGAGTTCGTTGTTTCCTTTCCGGTATGCCTGAACTT
AAATTAGGTATCAATGATAAGGCCTTTTATGATGCATAAGGGCGTACTTCTAAGAGTAGA
GCAATAGAATTTGATGATATGAAATTCCATGCCTGCGTGAGATTGTCGAAGTTTGAAAAT
GATAGAGTAATTTCATTCATTCCTCCTGATGGTGAATTTGAATTAGCTTCCTATCGTTTA
GATGTTCGTGTTAAGCCTCTATTTTCAGTTGAAGTTACTCCTGAAAGAAAGCCTAACTCT
AATAAAATTGAATTCACAGTTAAGGTAAAGAGTAATTTCAAGCAAAAATCTACTGCTAAT
AACGTTGAAATCTTTATCCCTGTACCTGATGATGCTGAAACCCCAGTTTTCAAGGCTGCT
TATGGTACTGTCGAATATGTTGCTGAAAAAGAAGCTATGGGATGGAAATTTAAGTAATTC
CCTGGCTAAAGAGAATACATGATGACAGCTACTTTCCACTTGCCTACTGTAGTATCTCCT
AATAGAGAAAAATTCTAAAGAATGCCAATCAGCATCAACTTCGAAATCCCTTACTACACC
GTAAGTGGTTTCTAAGTTAGATATTTAAAAATATAAGAAAAGAGTGGTTATCATGCTCTT
CCTTGGGTTCGTTATATTACATAAAATGGAGATTATCAAATTAGAATGTCTTGA

>TTHERM_01108620(protein)
MLYTYNQHLKNKILGRKTNNQLQKIKQKQQTNQEVNRQIDLEFIVYHQQIEGKSKQINKQ
LINKLISKQIVNTKYNQNSIEIIFQKYFKNQKAMSSCISTGISAIYILDHKGRVLITRCY
KGDLPINIHDIFNKKLLEYDEFSVKPILRDKYGHSFFYLHHNNLIFLAISRKNTNCMMVF
SFLYQLIQVLVDYFKELEEESVRDNFVIIYELLDEMMDNGYPQTTDNKILKGLIKTESHE
LKKDQKKPSKNSSLSIENQVDAITGAVTWRNNGISYKKNEVFLDVIEKLNMLVSHQGNVI
KSEIAGQIRVRCFLSGMPELKLGINDKAFYDAQGRTSKSRAIEFDDMKFHACVRLSKFEN
DRVISFIPPDGEFELASYRLDVRVKPLFSVEVTPERKPNSNKIEFTVKVKSNFKQKSTAN
NVEIFIPVPDDAETPVFKAAYGTVEYVAEKEAMGWKFKQFPGQREYMMTATFHLPTVVSP
NREKFQRMPISINFEIPYYTVSGFQVRYLKIQEKSGYHALPWVRYITQNGDYQIRMS

>TTHERM_01108620(gene)
ATGCTTTATACATACAATTAACATTTGAAAAATAAAATCTTAGGAAGGAAAACAAACAAC
CAACTATAAAAAATTAAATAAAAATAATAAACAAATTAAGAAGTGAATAGATAAATAGAT
CTTGAATTTATTGTTTATCATTAATAGATTGAAGGTAAAAGCAAATAAATAAATAAGCAA
TTAATTAATAAATTAATAAGTAAATAAATAGTTAATACAAAATACAACTAAAATAGCATA
GAAATCATTTTTTAAAAATATTTTAAGAATTAGAAAGCAATGTCATCCTGTATTAGTACT
GGTATTTCAGCCATCTATATTTTAGATCATAAGGGAAGAGTTCTCATCACAAGATGTTAT
AAAGGTGATTTGCCTATTAACATTCATGATATTTTCAACAAGAAATTGCTTGAATATGAT
GAATTCTCAGTTAAGCCTATTTTGCGTGATAAGTATGGTCACTCTTTCTTCTATTTACAT
CATAATAATTTGATCTTCTTAGCAATTTCTAGAAAGAATACTAACTGCATGATGGTGTTC
AGCTTCTTGTACCAACTTATTTAAGTTTTAGTAGATTATTTTAAGGAATTAGAAGAGGAA
TCTGTACGTGATAATTTTGTTATTATTTATGAACTACTTGATGAAATGATGGATAATGGT
TATCCCCAAACCACTGACAATAAGATTCTTAAAGGATTGATAAAGACTGAATCTCATGAG
TTGAAAAAAGATTAAAAAAAGCCAAGCAAGAATAGTTCTTTGTCAATCGAAAACTAAGTA
GATGCAATTACAGGTGCAGTTACTTGGAGAAACAATGGTATTTCTTACAAAAAGAATGAA
GTCTTTTTGGATGTTATTGAAAAATTAAATATGTTAGTTTCTCATCAAGGTAATGTCATT
AAGTCAGAAATAGCTGGTTAAATTAGAGTTCGTTGTTTCCTTTCCGGTATGCCTGAACTT
AAATTAGGTAAAATATTGCATAAAATTTAAAAGTTAGTTTGTTTGCAAGTTAATTTTGAA
AGAAGCAAATATCTTCAAAAAAAAAAAACACGTTTCTTTTTATTTTTGTTGCAGTTTTTA
AAAATAATTTTAGTGTTTTTAACTTTCGCATTCTGCAAAATCATTCTTCTGAATTGAAAA
TTTAGAAAGGCATTCTCCTCTAACATTTCAAATGCTTAAATTTTCGAGAATAAAATAGAT
TTAGGAATTGTCTTAGTTTTGAAAGTTAAAAAAATCAGCAATCATTAGGTTTAATTATTT
ATGACTTATAAAATTTATTTAGAGATCAATTAAAATTCAAAATTTTATTTAAAAATCGTC
TCTTCAGAAATCAATATAAAGCAGATATGAATTAATTAATACAAGAAACAAAAAAAATTA
TCTCACTCACAGATTAATGTTTTTCAATGAGGTGAGATAGTTGTTTCTGATATCTTTGAA
AAGCTCTCATTTTTAAGAGCAAGATTGAAAAATAAAATTCATTACACTTATATTTATTTA
TATTTTAAATCAGGTATCAATGATAAGGCCTTTTATGATGCATAAGGGCGTACTTCTAAG
AGTAGAGCAATAGAATTTGATGATATGAAATTCCATGCCTGCGTGAGATTGTCGAAGTTT
GAAAATGATAGAGTAATTTCATTCATTCCTCCTGATGGTGAATTTGAATTAGCTTCCTAT
CGTTTAGATGTTCGTGTTAAGCCTCTATTTTCAGTTGAAGTTACTCCTGAAAGAAAGCCT
AACTCTAATAAAATTGAATTCACAGTTAAGGTAAAGAGTAATTTCAAGCAAAAATCTACT
GCTAATAACGTTGAAATCTTTATCCCTGTACCTGATGATGCTGAAACCCCAGTTTTCAAG
GCTGCTTATGGTACTGTCGAATATGTTGCTGAAAAAGAAGCTATGGGATGGAAATTTAAG
TAATTCCCTGGCTAAAGAGAATACATGATGACAGCTACTTTCCACTTGCCTACTGTAGTA
TCTCCTAATAGAGAAAAATTCTAAAGAATGCCAATCAGCATCAACTTCGAAATCCCTTAC
TACACCGTAAGTGGTTTCTAAGTTAGATATTTAAAAATATAAGAAAAGAGTGGTTATCAT
GCTCTTCCTTGGGTTCGTTATATTACATAAAATGGAGATTATCAAATTAGAATGTCTTGA