Identifiers and Description

Gene Model Identifier

TTHERM_00519760

Standard Name

AOS1 (Activation Of Smt3p 1 )

Aliases

PreTt10771 | 64.m00251 | 3723.m00104

Description

ThiF family protein; ortholog of AOS1 in S. cerevisiae

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

No Data fetched for Gene Ontology Annotations

Domains

• ( PF00899 ) ThiF family
• ( TIGR02354 ) thiamine biosynthesis protein ThiF
• ( TIGR02355 ) molybdopterin synthase sulfurylase MoeB
• ( TIGR02356 ) thiazole biosynthesis adenylyltransferase ThiF
• ( TIGR00449 ) tRNA-guanine transglycosylases, various specificities

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.3%

TetraMine Data

TTHERM_00519760

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_15424.1	9.997093137033517e-262	ThiF family protein (373 aa)
Oxytricha	Contig11259.0.g51	1.9996410647472548e-29	ThiF family
SGD	YPR180W	2.999534586690157e-23	AOS1 Subunit of a heterodimeri c nuclear SUMO activating enzy me (E1) with Uba2p; activates Smt3p (SUMO) before its conjug ation to proteins (sumoylation ), which may play a role in pr otein targeting; essential for viability
DictyBase	DDB_G0279641	4.0009493637353324e-18	sae1 on chromosome: 3 position 2354365 to 2355712
WormBase	WBGene00000142	0.000000004999139696582238	locus:aos-1 SUMO-activating enzyme subunit aos-1 status: Confirmed UniProt:Q17820 p rotein_id:CAA96591.1

General Information

No Data fetched for General Information

Associated Literature

No Data fetched for Associated Literature

Sequences

>TTHERM_00519760(coding)
ATGGAAGTAGAATAAGTTTAGGAATAGTCTTAAAATTAAAAAGAAATTTCAAATGAAGAA
CTTTAAGTCTATGATAGACAAAGGTTCATAGGAGTTGAAGTATAAAAAAGATTATTAAAC
GCCAAAGTTTTTATCACTCCTGCAAATGGTGTTAACACAGAATTAGCAAAAAATTTAATT
CTTTGCGGTACAAATATATCAATTGCTGATAACGAGATTGTCAACTAGGATGATGTTGAA
ACAAATTTCCTTATTGCACCTCACGATTTAGGAAAAATAAGAGGTGAAGTTGTTAAAGCT
AAGCTATAAGATATGAATCCAATGGTTAAAATAGACCTTTATCAAACATTTGATATTAAG
TCATTTTACTAAAAATATATTCTTGAAAACAATGTTGATTGTTCTTTTACTAAAGAATTC
TTCAATTAATTCAATATAATAACTTCTTCAACTCCAATCTTTAAAGAAATGGAATTGTAT
GACGAAATAAGTCACTTTTTAAATATTCCTTATTACAACCAACTTTGCTGTGGTCTTTAT
GGTTTCTTTTATGTTTCTCTTGGCTCTCTATTCGAATTGACACAAGCTAAACCTAAGATA
TAAAAGACAAAAATTGTTTAAGGAAAACTTGTCAAAGAACCTATTTTATTTGAGTATTTC
CATAAAGTTAGCTTGAAATCAGAAAAATTAAAAAATTTCCTTGGAACAAATCCCAGAGGA
TCAAAGCCAGTATACCATGCAATTCAAATGATGAAAAGAGCAGAAGATTTAAATTTAAGA
TATGATCCTTACAATCACAGTGAGGAAAACTAAAAGGTTTTAGAATAAATAGTAGAGCTT
GCTCAAGAAAAAATTAAAAATGAGGAAGATAGAGAATTCTATACAAATTTTGCAAAATTC
TATGGAATTGAACACTGTCCAGTATACTCAGTTATTGGAAGTGTAGCAAGCCAAGAATTT
ATCAAAGTTATTGCCAAGGATAAAATGCCTGCCCTTAATTGGTTTGTATATGATAGCTAA
ATTGGATATGGTAAAATAGAAAGCTAAACTGATAAAATAGATGCAACATATGTAGATTTA
CCTGAGTTAACAAGAAAAGTTGAAGAATAGCAAGAATGA

>TTHERM_00519760(protein)
MEVEQVQEQSQNQKEISNEELQVYDRQRFIGVEVQKRLLNAKVFITPANGVNTELAKNLI
LCGTNISIADNEIVNQDDVETNFLIAPHDLGKIRGEVVKAKLQDMNPMVKIDLYQTFDIK
SFYQKYILENNVDCSFTKEFFNQFNIITSSTPIFKEMELYDEISHFLNIPYYNQLCCGLY
GFFYVSLGSLFELTQAKPKIQKTKIVQGKLVKEPILFEYFHKVSLKSEKLKNFLGTNPRG
SKPVYHAIQMMKRAEDLNLRYDPYNHSEENQKVLEQIVELAQEKIKNEEDREFYTNFAKF
YGIEHCPVYSVIGSVASQEFIKVIAKDKMPALNWFVYDSQIGYGKIESQTDKIDATYVDL
PELTRKVEEQQE

>TTHERM_00519760(gene)
ATGGAAGTAGAATAAGTTTAGGAATAGTCTTAAAATTAAAAAGAAATTTCAAATGAAGAA
CTTTAAGTCTATGATAGACAAAGGTTCATAGGAGTTGAAGTATAAAAAAGGTAATCTTTG
CAAATTATCATTTAAAAAAAGTAATTTATCTAATTTATCAAGATTATTAAACGCCAAAGT
TTTTATCACTCCTGCAAATGGTGTTAACACAGAATTAGCAAAAAATTTAATTCTTTGCGG
TACAAATATATCAATTGCTGATAACGAGATTGTCAACTAGGATGATGTTGAAACAAATTT
CCTTATTGCACCTCACGATTTAGGAAAAATAGTAATATTAAAAGAAATATCAATGCGCAA
TTTTTCTTATGAAAATTTATTTTGAAAATAGAGAGGTGAAGTTGTTAAAGCTAAGCTATA
AGATATGAATCCAATGGTTAAAATAGACCTTTATCAAACATTTGATATTAAGTCATTTTA
CTAAAAATATATTCTTGAAAACAATGTTGATTGTTCTTTTACTAAAGAATTCTTCAATTA
ATTCAATATAATAACTTCTTCAACTCCAATCTTTAAAGAAATGGTAAGTTAAATAAATAT
AAAACGAAATTTTATTTAAAAATGTTATTAATTAAATAATAAGGAATTGTATGACGAAAT
AAGTCACTTTTTAAATATTCCTTATTACAACCAACTTTGCTGTGGTCTTTATGGTTTCTT
TTATGTTTCTCTTGGCTCTCTATTCGAATTGACACAGTAATCAATTAATAAATAAATTAT
TTAATTAAATATCAAAGATATGCTTTTAAATTAAAGAAATAATATATCTTATTCTAACTT
TAAATAAATAAAAAAATAAAAGAGCTAAACCTAAGATATAAAAGACAAAAATTGTTTAAG
GAAAACTTGTCAAAGAACCTATTTTATTTGAGTATTTCCATAAAGTTAGCTTGAAATCAG
AAAAATTAAAAAATTTCCTTGGAACAAATCCCAGAGGATCAAAGCCAGTATACCATGCAA
TTCAAAGTAAATCAACTTTTCTTTAAATTATTATAATTAAATATATTGTGTCTACTTATT
TAAGTGATGAAAAGAGCAGAAGATTTAAATTTAAGATATGATCCTTACAATCACAGTGAG
GAAAACTAAAAGGTTTTAGAATAAATAGTAGAGCTTGCTCAAGAAAAAATTAAAAATGAG
GAAGATAGAGAATTCTATACAAATTTTGCAAAATTCTATGGAATTGAACACTGTCCAGTA
TACTCAGTTATTGGAAGTGTAGCAAGCCAAGAATTTATCAAAGTTATTGCCAGTAAGATT
CGTTTTATAATTTATTGAATTTGAAATATTTTTTAAAATTAATGTCTATTTTATATATAA
ATTTAAGAGGATAAAATGCCTGCCCTTAATTGGTTTGTATATGATAGCTAAATTGGATAT
GGTAAAATAGAAAGCTAAACTGATAAAATAGATGCAACATATGTAGATTTACCTGAGTTA
ACAAGAAAAGTTGAAGAATAGCAAGAATGA