Identifiers and Description

Gene Model Identifier

TTHERM_00704040

Standard Name

AMT1 (Adenine MethylTransferase (AMT) 1 targeting position N-six of Adenine)

Aliases

PreTt20179 | 110.m00152 | MTA1

Description

MT-a70 family protein; MT-A70 family protein; localizes to macronucleus

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• micronucleus (IDA) | GO:0031040 | Ref:SUPR000115

Molecular Function

• methyltransferase activity (IEA) | GO:0008168

Biological Process

• nucleobase-containing compound metabolic process (IEA) | GO:0006139

Domains

• ( PF05063 ) MT-A70
• ( PF01555 ) DNA methylase

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.8%

TetraMine Data

TTHERM_00704040

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_15256.1	9.997093137033517e-262	MT-A70 family protein (374 aa)
Oxytricha	Contig12701.0.0.g16	8.997297067630326e-99	MT-A70
SGD	YGL192W	1.0002124404074584e-26	IME4 Probable mRNA N6-adenosin e methyltransferase required f or entry into meiosis; transcr ibed in diploid cells; haploid s repress IME4 transcription v ia production of antisense IME 4 transcripts; antisense trans cription is repressed in diplo ids
Stentor Coeruleus	SteCoe_21805	3.1391327920480296e-17

General Information

No Data fetched for General Information

Associated Literature

1. Ref:31722409: Wang Y, Sheng Y, Liu Y, Zhang W, Cheng T, Duan L, Pan B, Qiao Y, Liu Y, Gao S (2019) A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription. Nucleic acids research 47(22):11771-11789

Sequences

>TTHERM_00704040(coding)
ATGAAGAAAGAATAATAATTTTTGATATTCAAGAAAAGTTTAATTATTGCGCAAAAAAGA
AAAGAAATTAATATTAAACAACTAAAATAACAATTTAAAAATTTTTTGTTTGTTTAGATT
TTTTCGATAATTAAATTAAAATTACAAGATATAATTATCAAGTTCAAAATGTCAAAAGCA
GTTAATAAAAAGGGATTGCGTCCCAGAAAGTCAGACTCAATTCTAGATCATATTAAGAAT
AAGTTAGATCAAGAATTCTTAGAGGATAATGAAAATGGTGAATAAAGTGATGAAGATTAC
GATTAAAAGTCTTTAAACAAAGCAAAAAAGCCATACAAAAAGAGATAAACTTAAAATGGA
TCTGAATTAGTTATTTCTCAATAAAAAACAAAAGCAAAAGCATCAGCAAATAATAAAAAA
AGTGCTAAAAATAGCCAGAAATTGGATGAAGAAGAAAAAATTGTTGAGGAAGAAGATTTA
TCTCCTCAAAAGAATGGTGCTGTATCTGAAGATGATTAGCAATAAGAAGCCTCTACATAA
GAGGATGACTACTTAGATAGATTACCTAAATCAAAAAAAGGACTTTAGGGATTATTATAA
GATATTGAAAAGAGAATTCTTCATTATAAATAATTATTTTTCAAAGAATAAAATGAAATA
GCTAATGGAAAAAGGAGTATGGTACCAGATAATTCAATTCCAATTTGCTCAGATGTTACA
AAACTTAATTTCTAAGCTTTAATAGATGCATAAATGAGACACGCTGGTAAGATGTTCGAT
GTTATTATGATGGATCCTCCTTGGTAACTCTCATCCTCTCAACCTTCAAGAGGTGTAGCT
ATTGCTTATGATTCTCTATCAGATGAAAAGATTTAAAACATGCCAATCCAATCTCTATAA
CAAGATGGATTTATTTTTGTTTGGGCAATTAATGCTAAATACAGAGTTACAATAAAAATG
ATTGAGAATTGGGGTTATAAATTAGTTGACGAAATAACTTGGGTAAAAAAGACTGTTAAT
GGTAAAATCGCAAAAGGACATGGATTCTACTTGCAACATGCTAAAGAAAGTTGTTTAATA
GGAGTAAAGGGAGATGTTGACAATGGCAGATTTAAAAAGAACATTGCTAGTGATGTTATT
TTTAGTGAAAGAAGAGGTTAAAGTTAGAAGCCTGAAGAAATTTATCAATATATAAATTAA
CTTTGTCCTAATGGAAATTATTTAGAAATCTTTGCCAGAAGAAATAATTTACATGATAAT
TGGGTTTCAATAGGAAATGAATTATGA

>TTHERM_00704040(protein)
MKKEQQFLIFKKSLIIAQKRKEINIKQLKQQFKNFLFVQIFSIIKLKLQDIIIKFKMSKA
VNKKGLRPRKSDSILDHIKNKLDQEFLEDNENGEQSDEDYDQKSLNKAKKPYKKRQTQNG
SELVISQQKTKAKASANNKKSAKNSQKLDEEEKIVEEEDLSPQKNGAVSEDDQQQEASTQ
EDDYLDRLPKSKKGLQGLLQDIEKRILHYKQLFFKEQNEIANGKRSMVPDNSIPICSDVT
KLNFQALIDAQMRHAGKMFDVIMMDPPWQLSSSQPSRGVAIAYDSLSDEKIQNMPIQSLQ
QDGFIFVWAINAKYRVTIKMIENWGYKLVDEITWVKKTVNGKIAKGHGFYLQHAKESCLI
GVKGDVDNGRFKKNIASDVIFSERRGQSQKPEEIYQYINQLCPNGNYLEIFARRNNLHDN
WVSIGNEL

>TTHERM_00704040(gene)
ATGAAGAAAGAATAATAATTTTTGATATTCAAGAAAAGTTTAATTATTGCGCAAAAAAGA
AAAGAAATTAATATTAAACAACTAAAATAACAATTTAAAAATTTTTTGTTTGTTTAGATT
TTTTCGATAATTAAATTAAAATTACAAGATATAATTATCAAGTTCAAAATGTCAAAAGCA
GTTAATAAAAAGGGATTGCGTCCCAGAAAGTCAGACTCAATTCTAGATCATATTAAGAAT
AAGTTAGATCAAGAATTCTTAGAGGATAATGAAAATGGTGAATAAAGTGATGAAGATTAC
GATTAAAAGTCTTTAAACAAAGCAAAAAAGCCATACAAAAAGAGATAAACTTAAAATGGA
TCTGAATTAGTTATTTCTCAATAAAAAACAAAAGCAAAAGCATCAGCAAATAATAAAAAA
AGTGCTAAAAATAGCCAGAAATTGGATGAAGAAGAAAAAATTGTTGAGGAAGAAGATTTA
TCTCCTCAAAAGAATGGTGCTGTATCTGAAGATGATTAGCAATAAGAAGCCTCTACATAA
GAGGATGACTACTTAGATAGATTACCTAAATCAAAAAAAGGACTTTAGGGATTATTATAA
GATATTGAAAAGAGAATTCTTCATTATAAATAATTATTTTTCAAAGAATAAAATGAAATA
GCTAATGGAAAAAGGAGTATGGTACCAGATAATTCAATTCCAATTTGCTCAGATGTTACA
AAACTTAATTTCTAAGCTTTAATAGATGCATAAATGAGACACGCTGGTAAGATGTTCGAT
GTTATTATGATGGATCCTCCTTGGTAACTCTCATCCTCTCAACCTTCAAGAGGTGTAGCT
ATTGCTTATGATTCTCTATCAGATGAAAAGATTTAAAACATGCCAATCCAATCTCTATAA
CAAGATGGATTTATTTTTGTTTGGGCAATTAATGCTAAATACAGGTATATATATATAAGC
ATTAAACAAAGCAATATTTTAAAATTTTTTAATGGAAAAATAGAGTTACAATAAAAATGA
TTGAGAATTGGGGTTATAAATTAGTTGACGAAATAACTTGGGTAAAAAAGACTGTTAATG
GTAAAATCGCAAAAGGACATGGATTCTACTTGCAACATGCTAAAGAAAGTTGTTTAATAG
GAGTAAAGGTAAGAAATTTATTTAAAAAGGTATTTAAAGTTAATAATTATTATTATTTTA
TAATCTCAAGGGAGATGTTGACAATGGCAGATTTAAAAAGAACATTGCTAGTGATGTTAT
TTTTAGTGAAAGAAGAGGTTAAAGTTAGAAGCCTGAAGAAATTTATCAATATATAAATTA
ACTTTGTCCTAATGGTATTATCAAACAAACCAAATATTTATTTGAATTGTATTTTATTTA
TTTTTTTTACATAATAAAAAAAATTAGGAAATTATTTAGAAATCTTTGCCAGAAGAAATA
ATTTACATGATAATTGGGTTTCAATAGGAAATGAATTATGA