Identifiers and Description

Gene Model Identifier

TTHERM_00088010

Standard Name

AFA1 (AAA Family ATPase 1)

Aliases

PreTt16451 | 6.m00525 | 3836.m02117 | QUEENB1

Description

AAA family ATPase; ATPase- AAA family protein; localizes to micronucleus during conjugation

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Cellular Component

• cytoplasm (IDA) | GO:0005737 | Ref:SUPR000209
• micronucleus (IDA) | GO:0031040 | Ref:SUPR000347
• ciliary tip (IDA) | GO:0097542 | Ref:SUPR000209
• oral apparatus (IDA) | GO:0031912 | Ref:SUPR000209
• cytoplasmic vesicle lumen (IDA) | GO:0060205 | Ref:SUPR000209

Molecular Function

• ATPase activity (IEA) | GO:0016887
• ATP binding (IEA) | GO:0005524

Domains

• ( TIGR02880 ) CbbX protein
• ( PF00004 ) ATPase, AAA family
• ( TIGR03263 ) guanylate kinase
• ( PF00158 ) Sigma-54 interaction domain
• ( TIGR02881 ) stage V sporulation protein K
• ( PF01078 ) Magnesium chelatase, subunit ChlI
• ( TIGR01242 ) 26S proteasome subunit P45 family
• ( TIGR00635 ) Holliday junction DNA helicase RuvB
• ( TIGR01241 ) ATP-dependent metallopeptidase HflB
• ( PF09336 ) Vps4 C terminal oligomerisation domain
• ( PF07724 ) ATPase family associated with various
• ( PF07726 ) ATPase family associated with various
• ( PF07728 ) ATPase family associated with various

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 9.9%

TetraMine Data

TTHERM_00088010

WebApollo

Fullscreen View

Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_02490.1	9.997093137033517e-262	ATPase, AAA family protein (74 6 aa)
Oxytricha	Contig1478.1.g58	1.9996385480812013e-123	ATPase family associated with various cellular activities (A AA)
DictyBase	DDB_G0268334	7.998584418911683e-103	DDB_G0268334 on chromosome: 1 position 714031 to 716367
WormBase	WBGene00017981	3.0006488705143073e-92	locus:figl-1 Fidgetin-like p rotein 1 status:Partially_co nfirmed UniProt:O16299 pro tein_id:CCD68481.1
SGD	YPL074W	7.998415523157811e-91	YTA6 Putative ATPase of the CD C48/PAS1/SEC18 (AAA) family, l ocalized to the cortex of moth er cells but not to daughter c ells
Stentor Coeruleus	SteCoe_15273	4.1863939993042314e-51

General Information

No Data fetched for General Information

Associated Literature

1. Ref:SUPR000209
2. Ref:SUPR000347

Sequences

>TTHERM_00088010(coding)
ATGCTTTCTACTTATAAAGATGCTGGGGATGGGGGATTGTAATAAGATAATTTAATTCCA
ATGTAGAAGGAAACCCTTAAGAGTATTTTATCCAGCTTTAAAAATAAGATGAATGAGACT
CATTAATTGTATTCTTAAAATTCAAACTCTCTTCAAAAAGAAGATAAAGAAGATGTATAT
AAACATGCTTTTTCTTTCGCTTTTCTACTTTAAAAGTATTAAGAGAAAGACAACTCACTA
TGTTTAGAAGATTTTATTTAAGAAGCTGAACGAATGAGAGATCATCAGTTATACAAACCA
AGCAAGGCTAATAAAAAGTTTAATATAATGCCAAAAATATCTAAAGAAAAGTTTGAGTAA
TTTATAGAATATGAAAAAGATACAAGATTTCCTCAACCTAGAAAAACAGTACAGTTAAAT
ACTCAAGCAAGACTTCCAGAAAGACAAACATCAAATTAAAAGCCTGCAATAAGTAGTTTA
TTGAATAGCAATAATAATTAAATCTCATCCAACTCTAATTAAGGATATGGGAATATAAAT
AGTTTTTAGAACAATCCTAATAATAGTATTGATAATAATAAAAATAATAATAATAATTTT
GGTCCTACTTAACAAAATAATAACAATGGGTTTTATAGATCTCAAAGCAGTTAAAATTAA
GATGAACAACCATAAAAAACAAATGGATATAAATAATAGTATAACAATGGCTACAACAGC
TATTAAAATTAAAATACAAATAATTTTGGGTATGGTAGAAATAGGTATCAAAATAACAAT
AGATATAATAAAGGAAGGGAGTAAATTGAAGAAGAATAAGATGAGTAATAGTAAGCTGGA
GGTTTTAAAACAGCATCAGAATAAAGATATTAAAATAATATGTTAAAGAGATAAAAAGAA
GAAGGATTCTATAATAAAGAAACTGGAAAATATGGTAGAAATAATGGATAGCTAGAGTTT
GAAGGTGTGAATGATAATAAACCTAAATACGGATATACAAAATATGGAAGTAACTAGGGA
GTTGATGATGTTGTTAATCTTGTCCATTACCATACTATAGGGAAAAACCTCAATTTAAAT
AATAATTCTTCATCTAATTAAGCTGCTGCCTTAAATGGAGGTGGTACAGAAGACGAATAT
AAAAAGACAGGACTAAGCAGAAAATTCAAACCTCCAGGAGCACCTGGTTCAAATACCGGA
GGGAAAAAAAATGAATAGTGTGAGCAGCTCAAAGGAATGGATTAAAAATTAATAGATTTA
ATTGAAAACGAAATTGTAGAAAATGCTGCTAATGTTAAGTGGGAAGATATAGCTGGTTTA
AGTTCAGCTAAGGAATCTGTCAAGGAAACTATAGTTTGGCCTATGTTGAACCCATAAATC
TTTACTGGTATTAGAGCTCCTCCTAAAGGTCTTCTCTTGTTTGGACCACCTGGAACAGGT
AAGACTATGATTGGCAAGGCTATTGCTAATCAATCTGGCTCTACATTTTTTTCTATATCA
GCATCTTCTCTAACAAGTAAATATATTGGTGAAGGTGAGAAAATGGTAAAAATTCTCTTC
AAGCTAGCAGAAATGAGATAACCAAGTGTTATTTTTATTGATGAAATAGACTCACTTTTA
TGTGCAAGATAAGAAAATGAAAATGAGGCAAGTAGAAGAATTAAGACAGAGTTTTTAGTT
TAAATGGAAGGTGCTACTTCAAGAGAAGAAGTAAGATTGTTACTTATAGGAGCAACAAAT
AGGCCATAAGAACTTGATGATGCTGTTAGAAGAAGATTTGTTAAGAAATTATATATTCCT
CTACCTAATATGGTAGCAAGAGAGTAATTGATAAGAAGAGTAATTGAAAGAGAATCAGCA
AAAGGAAACGCTTTTGATATGAGCGACCAAGATATTTTAGAAGTTGTTCAAGCTACAAAA
GGTTTTTCTGGAGCTGATATGACAAACCTTTGTAAGGAGGCAGCTTTAATACCTATCCGT
CAATGTACTGATATAACAAACATATAGTCTAGTGATATTCGTCCTATCAATAAATCAGAT
TTTGTAAAGTCACTAAAATAAGTTAAAGCTACAGTAACTTCAAAAGATTTAGCTGGATAT
TTTGATTGGAATAACTAATTTGGTAGTTTTGAAATAAATATGGAAGAAATAGATTCCTGA

>TTHERM_00088010(protein)
MLSTYKDAGDGGLQQDNLIPMQKETLKSILSSFKNKMNETHQLYSQNSNSLQKEDKEDVY
KHAFSFAFLLQKYQEKDNSLCLEDFIQEAERMRDHQLYKPSKANKKFNIMPKISKEKFEQ
FIEYEKDTRFPQPRKTVQLNTQARLPERQTSNQKPAISSLLNSNNNQISSNSNQGYGNIN
SFQNNPNNSIDNNKNNNNNFGPTQQNNNNGFYRSQSSQNQDEQPQKTNGYKQQYNNGYNS
YQNQNTNNFGYGRNRYQNNNRYNKGREQIEEEQDEQQQAGGFKTASEQRYQNNMLKRQKE
EGFYNKETGKYGRNNGQLEFEGVNDNKPKYGYTKYGSNQGVDDVVNLVHYHTIGKNLNLN
NNSSSNQAAALNGGGTEDEYKKTGLSRKFKPPGAPGSNTGGKKNEQCEQLKGMDQKLIDL
IENEIVENAANVKWEDIAGLSSAKESVKETIVWPMLNPQIFTGIRAPPKGLLLFGPPGTG
KTMIGKAIANQSGSTFFSISASSLTSKYIGEGEKMVKILFKLAEMRQPSVIFIDEIDSLL
CARQENENEASRRIKTEFLVQMEGATSREEVRLLLIGATNRPQELDDAVRRRFVKKLYIP
LPNMVAREQLIRRVIERESAKGNAFDMSDQDILEVVQATKGFSGADMTNLCKEAALIPIR
QCTDITNIQSSDIRPINKSDFVKSLKQVKATVTSKDLAGYFDWNNQFGSFEINMEEIDS

>TTHERM_00088010(gene)
ATGCTTTCTACTTATAAAGATGCTGGGGATGGGGGATTGTAATAAGATAATTTAATTCCA
ATGTAGAAGGAAACCCTTAAGAGTATTTTATCCAGCTTTAAAAATAAGATGAATGAGACT
CATTAATTGTATTCTTAAAATTCAAACTCTCTTCAAAAAGAAGATAAAGAAGATGTATAT
AAACATGCTTTTTCTTTCGCTTTTCTACTTTAAAAGTATTAAGAGAAAGACAACTCACTA
TGTTTAGAAGATTTTATTTAAGAAGCTGAACGAATGAGAGATCATCAGTTATACAAACCA
AGCAAGGCTAATAAAAAGTTTAATATAATGCCAAAAATATCTAAAGAAAAGTTTGAGTAA
TTTATAGAATATGAAAAAGATACAAGATTTCCTCAACCTAGAAAAACAGTACAGTTAAAT
ACTCAAGCAAGACTTCCAGAAAGACAAACATCAAATTAAAAGCCTGCAATAAGTAGTTTA
TTGAATAGCAATAATAATTAAATCTCATCCAACTCTAATTAAGGATATGGGAATATAAAT
AGTTTTTAGAACAATCCTAATAATAGTATTGATAATAATAAAAATAATAATAATAATTTT
GGTCCTACTTAACAAAATAATAACAATGGGTTTTATAGATCTCAAAGCAGTTAAAATTAA
GATGAACAACCATAAAAAACAAATGGATATAAATAATAGTATAACAATGGCTACAACAGC
TATTAAAATTAAAATACAAATAATTTTGGGTATGGTAGAAATAGGTATCAAAATAACAAT
AGATATAATAAAGGAAGGGAGTAAATTGAAGAAGAATAAGATGAGTAATAGTAAGCTGGA
GGTTTTAAAACAGCATCAGAATAAAGATATTAAAATAATATGTTAAAGAGATAAAAAGAA
GAAGGATTCTATAATAAAGAAACTGGAAAATATGGTAGAAATAATGGATAGCTAGAGTTT
GAAGGTGTGAATGATAATAAACCTAAATACGGATATACAAAATATGGAAGTAACTAGGGA
GTTGATGATGTTGTTAATCTTGTCCATTACCATACTATAGGGAAAAACCTCAATTTAAAT
AATAATTCTTCATCTAATTAAGCTGCTGCCTTAAATGGAGGTGGTACAGAAGACGAATAT
AAAAAGACAGGACTAAGCAGAAAATTCAAACCTCCAGGAGCACCTGGTTCAAATACCGGA
GGGAAAAAAAATGAATAGTGTGAGCAGCTCAAAGGAATGGATTAAAAAGTAAAATTTATT
AAAACAGATTTTAGTTATTAAAAATTTTTTTCATAAAGTTAATAGATTTAATTGAAAACG
AAATTGTAGAAAATGCTGCTAATGTTAAGTGGGAAGATATAGCTGGTTTAAGTTCAGCTA
AGGAATCTGTCAAGGAAACTATAGTTTGGCCTATGTTGAACCCATAAATCTTTACTGGTA
TTAGAGCTCCTCCTAAAGTAAAAAACATTTTAAATTTAATAGTTAATTTAATATTTAATT
ATAGGGTCTTCTCTTGTTTGGACCACCTGGAACAGGTAAGACTATGATTGGCAAGGCTAT
TGCTAATCAATCTGGCTCTACATTTTTTTCTATATCAGCATCTTCTCTAACAAGTAAATA
TATTGGTGAAGGTGAGAAAATGGTAAAAATTCTCTTCAAGCTAGCAGAAATGAGATAACC
AAGTGTTATTTTTATTGATGAAATAGACTCACTTTTATGTGCAAGATAAGAAGTAAAATA
AATAATAATAAAATTAAATATAAATTTATTTTAGCCTAATTGCTAAAATTTAAGATAAAA
CAAAAAATTATTTACAAATTTAAAATTTTTAGAATGAAAATGAGGCAAGTAGAAGAATTA
AGACAGAGTTTTTAGTTTAAATGGAAGGTGCTACTTCAAGAGAAGAAGTAAGATTGTTAC
TTATAGGAGCAACAAATAGGCCATAAGAACTTGATGATGTGATTAATTTTCAAAATTTTG
GATTTCATAATCTAATTTATTTTATTAATAGGCTGTTAGAAGAAGATTTGTTAAGAAATT
ATATATTCCTCTACCTAATATGGTAGCAAGAGAGTAATTGATAAGAAGAGTAATTGAAAG
AGAATCAGCAAAAGGAAACGCTTTTGATATGAGCGACCAAGTAAAAAATTAATTGCATAT
AAGAAATACTAAGAAGATAAATTATTCATTTTTAATTTTAAAAATTTATAATAAATAGGA
TATTTTAGAAGTTGTTCAAGCTACAAAAGGTTTTTCTGGAGCTGATATGACAAACCTTTG
TAAGGAGGCAGCTTTAATACCTATCCGTCAATGTACTGATATAACAAACATATAGTCTAG
TGATATTCGTCCTATCAATAAATCAGATTTTGTAAAGTCACTAAAATAAGTTAAAGCTAC
AGTAACTTCAAAAGATTTAGCTGGATATTTTGATTGGAATAACTAATTTGGTAGTTTTGA
AATAAATATGGAAGAAATAGATTCCTGA