Identifiers and Description

Gene Model Identifier

TTHERM_00715720

Standard Name

AAG1 (homolog of AlkylAdenine DNA Glycosylase 1)

Aliases

PreTt19046 | 113.m00085 | 3673.m00009

Description

3-methyladenine DNA glycosylase

Genome Browser (Macronucleus)

Genome Browser (Micronucleus)

Gene Ontology Annotations

Molecular Function

• alkylbase DNA N-glycosylase activity (IEA) | GO:0003905
• DNA binding (IEA) | GO:0003677

Biological Process

• base-excision repair (IEA) | GO:0006284

Domains

• ( TIGR00567 ) DNA-3-methyladenine glycosylase
• ( PF02245 ) Methylpurine-DNA glycosylase (MPG)

Gene Expression Profile

• Tetrahymena Functional Genomics Database:

Change in Gene Expression

TMHMM

TMHMM

Signal Peptide

Signal Peptide Present?: No
Presense Probability: 10.5%

TetraMine Data

TTHERM_00715720

WebApollo

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Tetrahymena Stock Center

No Data fetched for StockID

Homologs (v.2006 protein sequences)

Source	Identifier	Score	Description
Tetrahymena borealis	EI9_16844.1	1.9996161777617176e-164	DNA-3-methyladenine glycosylas e (241 aa)

General Information

No Data fetched for General Information

Associated Literature

1. Ref:23884606: Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y (2013) Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & development 27(15):1662-79

Sequences

>TTHERM_00715720(coding)
ATGTAAAAACAAAAAAGGCCACAAGAAGATATTGAACAGCCAAAGCAAAAATCTATATCA
GATTTTTTTGGAAAAAAGGCTAGCGCAAAGAAGGCTGATGATGATTAACTAAAATAAGTA
CCAGATAGCTTTTATGAAAAAGATGTTGTGACATTAGCATAAGATTTACTAGGAAAGCTG
ATTGTTCATAAAACAAAAGATGGGATAATTGCATGCAGGATAGTAGAAACTGAGGCTTAT
AAGGCTCCAGAAGATAAGGCGTGTCATGCGTATAAAAATAAAAAAACTGAAAAGACAAGC
TCATTTTGGCTTCCAGGAGGTCATGTATATATGTTTACAATTTATAATAATACTTGGTGC
TTTAATGTTGTTGCAGCCACAGCTGAAGAACCAGAAGCTGTTCTTGTTAGAGCTGTAGAG
CCAATTAAAGGACTCCATTTAATTCATAGAAATAGATCCTCACTGAAATCAAATAAAACC
GAAGATTTAGTTAATGGACCTGGAAAACTTACATTGGCTATGGGCATCACCAAAGAAAGA
AATGGATTTGATATGAGAGGAGAAGGAAAAGATTTATTTATAGCAGAATCACCTGAAAAT
TTAAAAAAGTTTGAAATAATTGCAAGCAAAAGAATAAATATAGATTATGCAGAAGAGTGG
ATAGATAAATATTGGAGGTTTACAATCAAAGATAATAAATTTGTTAGTGTTCCCTTGTAA
TTTTGA

>TTHERM_00715720(protein)
MQKQKRPQEDIEQPKQKSISDFFGKKASAKKADDDQLKQVPDSFYEKDVVTLAQDLLGKL
IVHKTKDGIIACRIVETEAYKAPEDKACHAYKNKKTEKTSSFWLPGGHVYMFTIYNNTWC
FNVVAATAEEPEAVLVRAVEPIKGLHLIHRNRSSLKSNKTEDLVNGPGKLTLAMGITKER
NGFDMRGEGKDLFIAESPENLKKFEIIASKRINIDYAEEWIDKYWRFTIKDNKFVSVPLQ
F

>TTHERM_00715720(gene)
ATGTAAAAACAAAAAAGGCCACAAGAAGATATTGAACAGCCAAAGCAAAAATCTATATCA
GATTTTTTTGGAAAAAAGGCTAGCGCAAAGAAGGCTGATGATGATTAACTAAAATAAGTA
CCAGATAGCTTTTATGAAAAAGATGTTGTGACATTAGCATAAGATTTACTAGGAAAGCTG
ATTGTTCATAAAACAAAAGATGGGATAATTGCATGCAGGATAGTAGAAACTGAGGCTTAT
AAGGCTCCAGAAGATAAGGCGTGTCATGCGTATAAAAATAAAAAAACTGAAAAGACAAGC
TCATTTTGGCTTCCAGGAGGTCATGTATATATGTTTACAATTTATAATAATACTTGGTGC
TTTAATGTTGTTGCAGCCACAGCTGAAGAACCAGAAGCTGTTCTTGTTAGGTATTTATTT
AAAATTCTTTTAAAATTTATTATTAACTTATTTATTTTTTATGTAGAGCTGTAGAGCCAA
TTAAAGGACTCCATTTAATTCATAGAAATAGATCCTCACTGAAATCAAATAAAACCGAAG
ATTTAGTTAATGGACCTGGAAAACTTACATTGGCTATGGGCATCACCAAAGAAAGAAATG
GATTTGATATGAGAGGAGAAGGAAAAGATTTATTTATAGCAGAATCACCTGAAAATTTAA
AAAAGTTTGAAATAATTGCAAGCAAAAGAATAAATATAGATTATGCAGAAGAGTGGATAG
ATAAATATTGGAGGTTTACAATCAAAGATAATAAATTTGTTAGTGTTCCCTTGTAATTTT
GA